PATTERN OF ANTIBIOTICS UTILIZATION IN NEONATAL SEPTICEMIA: A CROSS-SECTIONAL STUDY FROM RURAL TERTIARY CARE HOSPITAL WESTERN MAHARASHTRA, INDIA

Objective: To assess the quantification of use of antibiotics and to find out empiric antibiotic regimen practiced for neonatal sepsis in rural tertiary health care centre.Methods: A hospital, record based cross-sectional study was conducted in Neonatal Intensive Care Unit(NICU) at tertiary care hospital located in western Maharashtra, India. The study was planned during the year 2011-12 among 84 neonates with sepsis. Data were collected by using proforma includes demographic details, antibiotic prescriptions and relevant information.Results: Among the total 84 neonates, max, 60.71% had a history of term delivery. The proportion of early and late onset of sepsis was 47.61% and 52.38% for which total 18 antibiotics were used of which max, 88.88% were injectables. Amikacin was used in max, 78.57% neonates followed by cefotaxime, 45.23% and ampicillin, 35.71% in single or combination form respectively. Amikacin was used for max; 929 d followed by cefotaxime, 523 d and ampicillin 331 d respectively. Antibiotics used in single, double and multiple regimens were 19.04%, 46.42% and 34.52% respectively. Empiric antibiotic regimens practiced were cefotaxim+amikacin and cefotaxim+ampicillin, of which max, 80% patients were treated with the cefotaxim+amikacin antibiotic regimen. Out of 84 neonates max, 70% were improved at the time of discharge.Conclusion: Neonatal sepsis was well treated by cefotaxim+amikacin empirical injectable regimen with maximum survival

A Cross-cultural Comparison of Weekend–trips in Religious Tourism: Insights from two cultures, two countries (India and Italy)

This paper explains peculiarities, significance, and universality of weekend-trips as significant form of religious tourism using a comparative analysis of this phenomenon in two pilgrimage sites from two different cultures (and countries), namely, Vrindavan in India and the Shrine of Santimissi Medici in Italy. The findings derived from a case-study approach and visitors’ survey method confirm that religious tourism falls under the more general category of leisure and that visitors who flock to these places on weekends do not coincide either with general models proposed in the extant literature, nor can they be assimilated to the conventional categories of pilgrims and/or tourists. While highlighting the similarities and differences in the two cases, the paper proposes that weekend visitors are best described as religious tourists: visitors who use tourism as a means to fulfill a predominant religious motive in visiting a destination they consider religious or sacred. The analysis based on the concept of weekend-trips helps to explore nuances of religious tourism which can be used for better planning and management in religious tourism destinations

Antifungal properties of extracts of Ocimum tenuiflorum and Datura stramonium against some vegetable pathogenic fungi

A study was carried out to evaluate the antifungal properties of Ocimum tenuiflorum (also known as Ocimum sanctum) and Datura stramonium extracts on Fusarium oxysporum and Rhizopus stolonifer using the well in agar method. The in vitro studies have been performed by using leaf, stem bark and root bark chloroform, alcoholic and aqueous extracts. All extracts showed antifungal activity. The stem bark alcoholic extract of D. stramonium showed maximum activity; while minimum activity was observed with root aqueous extract of O. tenuiflorum against the fungi under investigation. Results showed that radial growth in all the test organisms was impaired by the addition of the extracts in the culture medium used. The test organisms differed in their reaction to the different extracts but on the whole, growth inhibition increased with the concentration of each extract. The antifungal activity for both the plants and for both the organisms was found is in increasing order i.e. root bark < leaves < stem bark

Immunoadjuvant potential of Azadirachta indica, Butea frondosa and Ficus religiosa against Swine flu vaccine antigen

Introduction: In general, primary or secondary metabolites derived from medicinal plant products might be responsible for stimulating or suppressing the immune system against specific protein antigens. The objective of this study was to evaluate the adjuvant potential of aqueous leaves extract of Azadirachta indica, Butea frondosa and Ficus religiosa against Swine flu vaccine antigen.Methods: In this study, our group evaluated the antibody (IgG) titre of Swine flu vaccine antigen (2 &mu;g/mL) using variable doses (0.625&ndash;5 mg) of aqueous leaves extract of A. indica, B. frondosa and F. religiosa. In addition, Swiss mice were immunized subcutaneously (100 &mu;L) on day 0 with Swine flu vaccine antigen (1:1000 dilution). Splenocytes were collected on day 7 and cultured with variable doses of aqueous leaves extract of A. indica, B. frondosa and F. religiosa pertaining to determine the total cellular content and splenocyte proliferation (Swine flu vaccine; Ovalbumin, OVA and Con A) assay. In addition, estimation of Th1 (IFN-gamma and TNF alpha) cytokines in cell culture supernatant containing swine flu vaccine antigen along with aqueous leaves extract were measured.Results: Aqueous leaves extract of A. indica, B. frondosa and F. religiosa showed anti-Swine flu titre at higher doses. In ex vivo animal model studies these three medicinal plants in the form of aqueous leaves extract enhanced total cellular content at higher doses but increased in splenocyte proliferation (Swine flu vaccine, OVA and Con A) assay at lower doses. Similarly, there was enhancement in Th1 cytokines (IFN-gamma, TNF alpha) with respect to swine flu vaccine antigen containing aqueous extract at lower doses as compared to control group.Conclusion: Aqueous leaves extract of A. indica, B. frondosa and F. religiosa showed adjuvant activity against Swine flu vaccine antigen and might be used in manufacturing active adjuvant for vaccine antigen

A Survey on Uncovering trending stories from Twitter by extracting ground truth from datasets

Today’s online social networking services generates series of conversation that shows the all kinds of real-world events, however the large amount of data are available on social network. This data can be filtered for finding trending topics using standard natural language processing techniques. An Uncovering trending stories is therefore a building block is to extract and summarizes the information raised from social networking services, this building block is very useful to find trending stories and its initiator .There are verity of methods that improves quality of result. This paper explores about different Topic detection method for uncovering trending topics from twitter datasets, such as Document-Pivot methods, Feature-Pivot methods, Frequent Pattern Mining, Soft Frequent Pattern Mining and BNgram

Sentimate Analysis For Web Product Ranking

Now a days web access is very important part of our day-to-day life. Everyone can do anything by using internet. Peoples are doing online shopping increasingly. Manufacturer sells their products through internet and users can buy anything from internet and also user has a permission to express their opinions. When user wants to buy something from internet they can read all the reviews of other peoples so that they can decide either this product is good or not. However it is impossible for customer to read all the product reviews. Therefore it is need of customer to summarize pros and cons so that customers can buy a product easily. In this paper we present a web product ranking system by using sentimate analysis. When user passes a query about any product he/she get back the ranking results. In this system we have also considered the phrases like either-or, not only-but also and so on. So this is practical and ranking results are interesting

Awareness, knowledge about breast feeding practices among urban mothers

Background: The knowledge and awareness about breast feeding practices is influenced by educational qualification, type of family and support from the family. Till date in India under- 5 mortality rate is mostly due to improper nutrition to the children since birth and infectious diseases among children. The aim of this study is to assess the knowledge and awareness about breast feeding practices among urban women attending a tertiary care hospital Chennai, India. Methods: This hospital based; prospective, cross-sectional study was carried out among 200 antenatal women who visited a tertiary care hospital in Chennai. The data regarding the knowledge and awareness about breast feeding practices was collected. Results: Knowledge about breast feeding practices like time of initiation, food that facilitate the secretion of breast milk is more among educated mothers. The type of family also showed a significant effect on the awareness about breast feeding. Proper posture of breast feeding was also not known to most of the antenatal mothers. Conclusions: Antenatal women had poor knowledge about the posture of breast feeding, but awareness about the initiation of breast feeding, period of breast feeding and weaning period was satisfactory. Awareness about breast milk banking and storage of breast milk was also poor

MINERAL ANALYSIS OF AVERRHOA BILIMBI L. – A POTENTIAL FRUIT

Averrhoa bilimbi L. (Oxalidaceae) is widely distributed and cultivated throughout tropical countries for their fruits. Parts such as leaves, bark, fruits are widely used in medicine as a folk remedy for many symptoms. This study provides morphological and biochemical characteristics of half-ripen bilimbi fruits. During present study physical and chemical properties of Bilimbi fruits were studied at half-ripen stage for potential benefits based on its mineral content. Phosphorus content of the fruits was higher at half-ripen stage i.e. 39 ± 1.7%, while in case of minor elements, Molybdenum is present in least amount i.e. 0.04 ± 0.05 ppm.  This Chemical studies reveals; these fruits are good source of minerals such as Potassium, Phosphorus, Nitrogen, Calcium, Magnesium and Iron suggesting its use as a potential fruit.Keywords: Averrhoa, Bilimbi, Mineral analysis, Oxalidaceae

Prospective study of ovarian function in hysterectomised females

Background: Hysterectomy is one of the most common operations performed in the world. The aim of this study was to determine prospectively the influence of hysterectomy on ovarian function by measuring gonadotrophin levels and studying ovarian doppler over a two-year period.Methods: Authors conducted a prospective cohort study at the department of obstetrics and gynecology in study tertiary care center. The study was carried out over a period of two years November 2012-November 2014. Serum FSH, ovarian PI and questionnaire data were obtained at baseline and at 6 and 12 months postoperatively.Results: There was significant difference in the mean FSH and mean PI at follow-up visits of 6 and 12 months. Patient characteristics did not contribute to the changes that were observed during the follow-up.Conclusions: Authors conclude that hysterectomy affects ovarian function by affecting blood supply (reducing blood supply). This is reflected by increased FSH levels and increased PI values on ovarian Doppler