1 research outputs found
Development of ProPhenol/Ti(IV) Catalyst for Asymmetric Hydroxylative Dearomatization of Naphthols
By development of ProPhenol/Ti(IV) catalysts, a catalytic
enantioselective
hydroxylative dearomatization of naphthols is achieved by using TBHP
as a simple oxidative reagent. The side coordinative chain equipped
on the C1-position of β-naphthols plays an important role for
initiating this asymmetric hydroxylative reaction, which might be
a result of the proper cocoordination effects to the titanium center
in the catalyst. A reasonable catalytic cycle is proposed, the catalytic
system is applied to a reasonable range of this type of phenolic compound,
and related concise transformations are carried out