5 research outputs found
The Effect of the Diving/Wet Suit on the Survival Time in Cold Water Immersion
In this study, we will compare the effect of normal clothes (assumed as bare skin) with effect of wetsuit in maintaining the core body temperature, produced by metabolic heat generations and blood flow heat generation, using COMSOL. A passenger is immersed in cold water after Titanic has shipwrecked, and the individual is waiting for rescue to come in time before his metabolic functions stop and die. We will compare two cases: with and without wetsuit on the passenger. Skin temperature or wetsuit temperature is assumed to be equal to cold water temperature, which is at 10 degrees Celsius, and the distribution of temperature throughout the body will be graphically shown as the time of body immersion in water increases. It is shown from the results that wetsuit can help maintain the normal core body temperature much longer than normal clothes/bare skin can in cold water immersion
Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NC/Nga Mice
Atopic dermatitis (AD) is a common inflammatory skin disease. The increasing prevalence and severity of AD have prompted the developments of safer, more effective drugs. Although topical corticosteroids have been used as first line therapy for AD, their potential side effects limit their clinical applications. To investigate the effect of hirsutenone (HIR), a diarylheptanoid compound, on AD-like skin lesions and other factors related to immune response is the aim of this paper Th2-related cytokines (IL-4, IL-5, IL-13), eosinophil, IgE inflammatory factors (COX-2, iNOS) levels were reduced in blood, lymphocytes, and tissue after HIR treatment. These results suggest that HIR might be an effective treatment for AD
Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NC/Nga Mice
Atopic dermatitis (AD) is a common inflammatory skin disease. The increasing prevalence and severity of AD have prompted the developments of safer, more effective drugs. Although topical corticosteroids have been used as first line therapy for AD, their potential side effects limit their clinical applications. To investigate the effect of hirsutenone (HIR), a diarylheptanoid compound, on AD-like skin lesions and other factors related to immune response is the aim of this paper Th2-related cytokines (IL-4, IL-5, IL-13), eosinophil, IgE inflammatory factors (COX-2, iNOS) levels were reduced in blood, lymphocytes, and tissue after HIR treatment. These results suggest that HIR might be an effective treatment for AD