6.EMEA International Symposium in Kanazawa, Japan

金沢大学大学院自然科学研究科Project Number 14404021, Peport of Research Project ; Grant-in-Aid for Scientific Research(B)(2), from April 2002 to March 2006, Edited by Muramoto,Ken-ichiroKamata, NaotoKawanishi, TakuyaKubo, MamoruLiu, JiyuanLee, Kyu-Sung , 人工衛星データ活用のための東アジアの植生調査、課題番号14404021, 平成14年度～平成17年度科学研究費補助金, 基盤研究（B)(2)研究成果報告書, 研究代表者：村本, 健一郎, 金沢大学自然科学研究科教

Geostatistical modeling for forest management using IKONOS imagery

金沢大学大学院自然科学研究科2005 International Symposium on Environmental Mornitoring in East Asia -Remote Sensing and Forests-,Hosted The EMEA Project, Kanazawa University 21st=Century COE Program -Environmental Monitoring and Predicition of Long- and Short- Term Dynamics of Pan-Japan Sea Area- ,予稿集, EMEA 2005 in Kanazawa, 国際学術研究公開シンポジウム『東アジアの環境モニタリング』－リモートセンシングと森林－,年月日：200511月28日～29日, 場所：KKRホテル金沢, 金沢大学自然科学研究科, 主催：金沢大学EMEAプロジェクト, 共催：金沢大学21世紀COEプログラム「環日本海域の環境変動と長期・短期変動予測

Preliminary Results from a Multi-center Prospective Study (JROSG 05-5) on Postoperative Radiotherapy for Patients with High-risk Ductal Carcinoma in situ with Involved Margins or Margin Widths 1 mm or less than

Abstract Purpose: This prospective study aimed to evaluate the effectiveness of postoperative radiotherapy (PORT) consisting of whole breast irradiation followed by boost irradiation in patients with high-risk ductal carcinoma in situ (DCIS) with margin widths less than 1 mm. Materials and Methods: A multi-center phase II study (Japanese Radiation Oncology Study Group: JROSG 05-5) was conducted to evaluate the effectiveness of PORT. PORT consisted of whole breast irradiation (50 Gy/25 fractions) followed by boost irradiation (10 Gy/5 fractions) using electron beams for patients with high-risk DCIS. Eligibility criteria were as follows: 1) DCIS without an invasive carcinoma component, 2) age between 20 and 80 years, 3) involved margins or margin widths less than 1 mm, 4) refusal of re-resection, 5) performance status of 0−2, and 6) written informed consent. The primary endpoint was ipsilateral breast tumor recurrence (IBTR), and secondary endpoints were overall survival, relapse-free survival, recurrence patterns, and adverse events. Conclusions: Our preliminary results suggest that this PORT schedule may be promising for patients with high-risk DCIS. However, to make any definitive conclusions, a longer follow-up time is required

Development of a Compact Divertor Plasma Simulator for Plasma-Wall Interaction Studies on Neutron-Irradiated Materials

We have developed a compact divertor plasma simulator (CDPS) that can produce steady-state deuterium and/or helium plasmas with densities above ∼ 1018 m−3 for Plasma-Wall Interaction (PWI) studies of neutron-irradiated materials. The maximum particle flux is about 1022 m−2s−1. The CDPS was installed and is being operated in the radiation-controlled area of the International Research Center for Nuclear Materials Science, Institute for Materials Research, Tohoku University. We are able to control sample temperature within uncertainty of 5 °C during plasma exposure by adjusting the cooling air flow rate to the sample holder. The CDPS has a sample-carrier system, which makes it possible to transfer a plasma-irradiated sample from the sample holder to an infrared heater for analysis using thermal desorption spectroscopy (TDS) without exposing it to the air. This avoids the oxidation of the sample and minimizes the time between the end of plasma exposure and TDS analysis. An ITER-like tungsten (W) sample (A.L.M.T. Corp.), which has been irradiated by neutrons to 0.06 dpa in a fission reactor, was exposed to a deuterium plasma in the CDPS. The experimental results clearly show that the total deuterium retention in the neutron-irradiated W sample increases significantly in comparison with a pristine W, as demonstrated by broadening of the TDS spectrum at high temperatures

Quality Assurance in the Prospective Multi-institutional Trial on Definitive Radiotherapy Using High-dose-rate Intracavitary Bracheytherapy for Uterine Cervical Cancer: The Individual Case Review

Objective: To assess compliance with the radiotherapy protocol of a multi-institutional prospective study (JAROG0401/JROSG04-2), which investigated the efficacy and toxicity of definitive radiotherapy using high-dose-rate intracavitary brachytherapy (HDR-ICBT) for early-stage uterine cervical cancer patients.\nMethods: Individual case reviews (ICRs) were performed on all 60 study participants. Radiotherapy data were submitted to the quality assurance (QA) committee, which performed ICRs on 16 QA items according to previously selected criteria. The items focused on quality of external beam radiotherapy (EBRT), HDR-ICBT and both. Each item was determined to be either acceptable or a deviation. The QA committee performed ICR three times as planned, two during the patient accrual and the final one just after the final patient accrued. The QA results of the first and second reviews were reported back to the investigators after each ICR.\nResults: In 40 cases (67%), all 16 QA items were classified as acceptable. One deviation was found in 16 cases, two deviations were identified in 3 cases and three deviations were noted in 1 case. The most frequently observed deviation was missing the rules for determining point A (10 cases). The items described by quantitative values, such as prescribed doses, certain time intervals and overall treatment time, were well followed. The proportion of deviations gradually decreased during the ICR process.\nConclusions: The present ICR demonstrated the favorable radiotherapy compliance with the JAROG0401/JROSG04-2 protocol. The QA process using ICRs can potentially be used to improve the quality of radiotherapy, including HDR-ICBT in the multi-institutional prospective studies for cervical cancer

Outcomes of Pregnancies and Deliveries of Patients Who Underwent Fertility-Preserving Surgery for Early-Stage Epithelial Ovarian Cancer

Some studies have shown increased risks of preterm birth, low birth weight, and cesarean delivery after oncologic treatment; others have shown the opposite. We evaluated the outcomes of pregnancies and deliveries of patients who underwent fertility-preserving surgery (FSS) for early-stage epithelial ovarian cancer (EOC) and examined their perinatal prognosis. This retrospective study included women with a history of stage IA or IC ovarian cancer reported in our previous study. The primary outcome was preterm birth after cancer diagnosis was considered. Secondary outcomes were neonatal morbidity and severe maternal morbidity. Thirty-one children were born to 25 women who had undergone FSS. The mean number of weeks at delivery was 38.7 ± 0.7, and the mean birth weight of infants was 3021 ± 160 g. With respect to pregnancy outcomes, 5 patients had preterm labor and 26 had full-term labor. The delivery mode was vaginal delivery in 18 patients and cesarean delivery in 13. Complications during pregnancy included placenta previa (one case) and pelvic abscess (one case). Except for three preterm infants with low birth weight, there were no other perinatal abnormalities. Pregnancy after fertility preservation in EOC has an excellent perinatal prognosis, although the cesarean delivery rate is high