402 research outputs found

    Dynamic response of a polymer-stabilized blue-phase liquid crystal

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    Fast response time is the most attractive feature of polymer-stabilized blue phase liquid crystals (PS-BPLCs). We have investigated the dynamic response of a PS-BPLC under various electric fields and found that the response time becomes slower as the applied electric field exceeds a critical field. Further analyses of experimental data reveal that two relaxation processes are involved. Possible mechanism is proposed to explain the behavior of each process. These results provide useful guidelines for achieving fast response time without hysteresis

    Jaundice, occult blood and acute cholecystitis: hemobilia as the initial presentation of acute cholecystitis complicated by a pseudoaneurysm

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    Identifying the presence of hemobilia can be clinically important since it might change the therapeutic approach to patient management. Here, we report a 56-year-old man with clinical symptoms of acute cholecystitis. Multidetector-row computed tomography of the abdomen showed a ruptured pseudoaneurysm arising from the right hepatic artery. Angiography, with transarterial coil embolization of the pseudoaneurysm, was performed before surgery to reduce the risk of hemostatic complications

    A microsecond-response polymer-stabilized blue phase liquid crystal

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    A polymer-stabilized blue-phase liquid crystal (BPLC) with microsecond response time is demonstrated using a vertical field switching cell. The measured decay time is 39 mu s at room temperature (21 degrees C) and then decreases to 9.6 mu s at 44.3 degrees C. Such a response time is 1-2 orders of magnitude faster than that of a typical BPLC device. The responsible physical mechanisms are the collective effects of short pitch length, strong polymer network, and low viscosity through temperature effect. The on-state voltage of our BPLC device is 44.2 V, hysteresis is below 0.7%, and contrast ratio is over 1300:1

    Unraveling the Role of the rssC Gene of Serratia marcescens by Atomic Force Microscopy

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    100學年度研究獎補助論文[[abstract]]The product and direct role of the rssC gene of Serratia marcescens is unknown. For unraveling the role of the rssC gene, atomic force microscopy has been used to identify the surfaces of intact S. marcescens wild-type CH-1 cells and rssC mutant CH-1ΔC cells. The detailed surface topographies were directly visualized, and quantitative measurements of the physical properties of the membrane structures were provided. CH-1 and CH-1ΔC cells were observed before and after treatment with lysozyme, and their topography-related parameters, e.g., a valley-to-peak distance, mean height, surface roughness, and surface root-mean-square values, were defined and compared. The data obtained suggest that the cellular surface topography of mutant CH-1ΔC becomes rougher and more precipitous than that of wild-type CH-1 cells. Moreover, it was found that, compared with native wild-type CH-1, the cellular surface topography of lysozyme-treated CH-1 was not changed profoundly. The product of the rssC gene is thus predicted to be mainly responsible for fatty-acid biosynthesis of the S. marcescens outer membrane. This study represents the first direct observation of the structural changes in membranes of bacterial mutant cells and offers a new prospect for predicting gene expression in bacterial cells.[[journaltype]]國外[[incitationindex]]SCI[[booktype]]紙本[[countrycodes]]GB

    Dichlorido{(E)-2,4,6-trimethyl-N-[phen­yl(2-pyridyl)methyl­idene]aniline-κ2 N,N′}palladium(II)

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    The title complex, [PdCl2(C21H20N2)], contains a PdII atom in a slightly distorted square-planar coordination environment defined by two N atoms from one 2,4,6-trimethyl-N-[phen­yl(2-pyrid­yl)methyl­idene]aniline ligand and two Cl atoms, forming a five-membered ring (N—Pd—N—C—C)

    Transcriptome analysis of Dnmt3l knock-out mice derived multipotent mesenchymal stem/stromal cells during osteogenic differentiation

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    Multipotent mesenchymal stem/stromal cells (MSCs) exhibit great potential for cell-based therapy. Proper epigenomic signatures in MSCs are important for the maintenance and the subsequent differentiation potential. The DNA methyltransferase 3-like (DNMT3L) that was mainly expressed in the embryonic stem (ES) cells and the developing germ cells plays an important role in shaping the epigenetic landscape. Here, we report the reduced colony forming ability and impaire

    Dielectric dispersion on the Kerr constant of blue phase liquid crystals

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    Dielectric dispersions on the Kerr constant of two polymer-stabilized blue phase liquid crystals (BPLCs) are investigated. An extended Cole-Cole model is proposed to fit the experimental results and good agreement is obtained. As the electric field frequency increases, Kerr constant decreases and the associated dielectric heating effect gradually increases. These results will undoubtedly affect the high frequency operation of BPLC devices

    Association of clinical symptomatic hypoglycemia with cardiovascular events and total mortality in type 2 diabetes a nationwide population-based study

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    OBJECTIVE Hypoglycemia is associated with serious health outcomes for patients treated for diabetes. However, the outcome of outpatients with type 2 diabetes who have experienced hypoglycemia episodes is largely unknown. RESEARCH DESIGN AND METHODS The study population, derived from the National Health Insurance Research Database released by the Taiwan National Health Research Institutes during 1998–2009, comprised 77,611 patients with newly diagnosed type 2 diabetes. We designed a prospective study consisting of randomly selected hypoglycemic type 2 diabetic patients and matched type 2 diabetic patients without hypoglycemia. We investigated the relationships of hypoglycemia with total mortality and cardiovascular events, including stroke, coronary heart disease, cardiovascular diseases, and all-cause hospitalization. RESULTS There were 1,844 hypoglycemic events (500 inpatients and 1,344 outpatients) among the 77,611 patients. Both mild (outpatient) and severe (inpatient) hypoglycemia cases had a higher percentage of comorbidities, including hypertension, renal diseases, cancer, stroke, and heart disease. In multivariate Cox regression models, including diabetes treatment adjustment, diabetic patients with hypoglycemia had a significantly higher risk of cardiovascular events during clinical treatment periods. After constructing a model adjusted with propensity scores, mild and severe hypoglycemia still demonstrated higher hazard ratios (HRs) for cardiovascular diseases (HR 2.09 [95% CI 1.63–2.67]), all-cause hospitalization (2.51 [2.00–3.16]), and total mortality (2.48 [1.41–4.38]). CONCLUSIONS Symptomatic hypoglycemia, whether clinically mild or severe, is associated with an increased risk of cardiovascular events, all-cause hospitalization, and all-cause mortality. More attention may be needed for diabetic patients with hypoglycemic episodes.Pai-Feng Hsu, Shih-Hsien Sung, Hao-Min Cheng, Jong-Shiuan Yeh, Wen-Ling Liu, Wan-Leong Chan, Chen-Huan Chen, Pesus Chou, Shao-Yuan Chuan
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