Complete gradient-LC-ESI system on a chip for protein analysis

This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis

Time-bin entangled photon holes

The general concept of entangled photon holes is based on a correlated absence of photon pairs in an otherwise constant optical background. Here we consider the specialized case when this background is confined to two well-defined time bins, which allows the formation of time-bin entangled photon holes. We show that when the typical coherent state background is replaced by a true single-photon (Fock state) background, the basic time-bin entangled photon-hole state becomes equivalent to one of the time-bin entangled photon-pair states. We experimentally demonstrate these ideas using a parametric down-conversion photon-pair source, linear optics, and post-selection to violate a Bell inequality with time-bin entangled photon holes.Comment: 6 pages, 5 figure

Quantum interference by two temporally distinguishable pulses

We report a two-photon interference effect, in which the entangled photon pairs are generated from two laser pulses well-separated in time. In a single pump pulse case, interference effects did not occur in our experimental scheme. However, by introducing a second pump pulse delayed in time, quantum interference was then observed. The visibility of the interference fringes shows dependence on the delay time between two laser pulses. The results are explained in terms of indistinguishability of biphoton amplitudes which originated from two temporally separated laser pulses.Comment: two-column, 4pages, submitted to PRA, minor change

Induced Coherence and Stable Soliton Spiraling

We develop a theory of soliton spiraling in a bulk nonlinear medium and reveal a new physical mechanism: periodic power exchange via induced coherence, which can lead to stable spiraling and the formation of dynamical two-soliton states. Our theory not only explains earlier observations, but provides a number of predictions which are also verified experimentally. Finally, we show theoretically and experimentally that soliton spiraling can be controled by the degree of mutual initial coherence.Comment: 4 pages, 5 figure

Kinetic Inductance of Josephson Junction Arrays: Dynamic and Equilibrium Calculations

We show analytically that the inverse kinetic inductance $L^{-1}$ of an overdamped junction array at low frequencies is proportional to the admittance of an inhomogeneous equivalent impedance network. The $ij^{th}$ bond in this equivalent network has an inverse inductance $J_{ij}\cos(\theta_i^0-\theta_j^0-A_{ij})$, where $J_{ij}$ is the Josephson coupling energy of the $ij^{th}$ bond, $\theta_i^0$ is the ground-state phase of the grain $i$, and $A_{ij}$ is the usual magnetic phase factor. We use this theorem to calculate $L^{-1}$ for square arrays as large as $180\times 180$. The calculated $L^{-1}$ is in very good agreement with the low-temperature limit of the helicity modulus $\gamma$ calculated by conventional equilibrium Monte Carlo techniques. However, the finite temperature structure of $\gamma$, as a function of magnetic field, is \underline{sharper} than the zero-temperature $L^{-1}$, which shows surprisingly weak structure. In triangular arrays, the equilibrium calculation of $\gamma$ yields a series of peaks at frustrations $f = \frac{1}{2}(1-1/N)$, where $N$ is an integer $\geq 2$, consistent with experiment.Comment: 14 pages + 6 postscript figures, 3.0 REVTe

New high-efficiency source of photon pairs for engineering quantum entanglement

We have constructed an efficient source of photon pairs using a waveguide-type nonlinear device and performed a two-photon interference experiment with an unbalanced Michelson interferometer. Parametric down-converted photons from the nonlinear device are detected by two detectors located at the output ports of the interferometer. Because the interferometer is constructed with two optical paths of different length, photons from the shorter path arrive at the detector earlier than those from the longer path. We find that the difference of arrival time and the time window of the coincidence counter are important parameters which determine the boundary between the classical and quantum regime. When the time window of the coincidence counter is smaller than the arrival time difference, fringes of high visibility (80$\pm$ 10%) were observed. This result is only explained by quantum theory and is clear evidence for quantum entanglement of the interferometer's optical paths.Comment: 4 pages, 4 figures, IQEC200

Kinematical Analogy for Marginal Dyon Decay

We describe a kinematical analogy for the marginal decay of 1/4-BPS dyons in 4-dimensional N=4 string compactifications. In this analogy, the electric and magnetic charges play the role of spatial momenta, the BPS mass plays the role of energy, and 1/2-BPS dyons correspond to massless particles. Using SO(12,1) "Lorentz" invariance and standard kinematical formulae in particle physics, we provide simple derivations of the curves of marginal stability. We also show how these curves map into the momentum ellipsoid, and propose some applications of this analogy.Comment: 10 pages, minor revision

Prefrontal High Gamma in ECoG Tags Periodicity of Musical Rhythms in Perception and Imagination

Rhythmic auditory stimuli are known to elicit matching activity patterns in neural populations. Furthermore, recent research has established the particular importance of high-gamma brain activity in auditory processing by showing its involvement in auditory phrase segmentation and envelope tracking. Here, we use electrocorticographic (ECoG) recordings from eight human listeners to see whether periodicities in high-gamma activity track the periodicities in the envelope of musical rhythms during rhythm perception and imagination. Rhythm imagination was elicited by instructing participants to imagine the rhythm to continue during pauses of several repetitions. To identify electrodes whose periodicities in high-gamma activity track the periodicities in the musical rhythms, we compute the correlation between the autocorrelations (ACCs) of both the musical rhythms and the neural signals. A condition in which participants listened to white noise was used to establish a baseline. High-gamma autocorrelations in auditory areas in the superior temporal gyrus and in frontal areas on both hemispheres significantly matched the autocorrelations of the musical rhythms. Overall, numerous significant electrodes are observed on the right hemisphere. Of particular interest is a large cluster of electrodes in the right prefrontal cortex that is active during both rhythm perception and imagination. This indicates conscious processing of the rhythms\u27 structure as opposed to mere auditory phenomena. The autocorrelation approach clearly highlights that high-gamma activity measured from cortical electrodes tracks both attended and imagined rhythms