Complete gradient-LC-ESI system on a chip for protein analysis

This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis

Reynolds stress models of homogeneous turbulence

Existing and new models for the rapid and the return terms in the Reynolds stress equations were tested in two ways. One, by direct comparison of the model with simulation data. The other, by simulating the flows using the models and comparing the predicted Reynolds stresses with the data. It was found that existing linear models can be improved and that nonlinear models are in better agreement with the simulation data for a wide variety of flows

Simulation of valveless micropump and mode analysis

In this work, a 3-D simulation is performed to study for the solid-fluid coupling effect driven by piezoelectric materials and utilizes asymmetric obstacles to control the flow direction. The result of simulation is also verified. For a micropump, it is crucial to find the optimal working frequency which produce maximum net flow rate. The PZT plate vibrates under the first mode, which is symmetric. Adjusting the working frequency, the maximum flow rate can be obtained. For the micrpump we studied, the optimal working frequency is 3.2K Hz. At higher working frequency, say 20K Hz, the fluid-solid membrane may come out a intermediate mode, which is different from the first mode and the second mode. It is observed that the center of the mode drifts. Meanwhile, the result shows that a phase shift lagging when the excitation force exists in the vibration response. Finally, at even higher working frequency, say 30K Hz, a second vibration mode is observed.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/EDA-Publishing

Quantum interference by two temporally distinguishable pulses

We report a two-photon interference effect, in which the entangled photon pairs are generated from two laser pulses well-separated in time. In a single pump pulse case, interference effects did not occur in our experimental scheme. However, by introducing a second pump pulse delayed in time, quantum interference was then observed. The visibility of the interference fringes shows dependence on the delay time between two laser pulses. The results are explained in terms of indistinguishability of biphoton amplitudes which originated from two temporally separated laser pulses.Comment: two-column, 4pages, submitted to PRA, minor change

New high-efficiency source of photon pairs for engineering quantum entanglement

We have constructed an efficient source of photon pairs using a waveguide-type nonlinear device and performed a two-photon interference experiment with an unbalanced Michelson interferometer. Parametric down-converted photons from the nonlinear device are detected by two detectors located at the output ports of the interferometer. Because the interferometer is constructed with two optical paths of different length, photons from the shorter path arrive at the detector earlier than those from the longer path. We find that the difference of arrival time and the time window of the coincidence counter are important parameters which determine the boundary between the classical and quantum regime. When the time window of the coincidence counter is smaller than the arrival time difference, fringes of high visibility (80$\pm$ 10%) were observed. This result is only explained by quantum theory and is clear evidence for quantum entanglement of the interferometer's optical paths.Comment: 4 pages, 4 figures, IQEC200

Learning Temporal Transformations From Time-Lapse Videos

Based on life-long observations of physical, chemical, and biologic phenomena in the natural world, humans can often easily picture in their minds what an object will look like in the future. But, what about computers? In this paper, we learn computational models of object transformations from time-lapse videos. In particular, we explore the use of generative models to create depictions of objects at future times. These models explore several different prediction tasks: generating a future state given a single depiction of an object, generating a future state given two depictions of an object at different times, and generating future states recursively in a recurrent framework. We provide both qualitative and quantitative evaluations of the generated results, and also conduct a human evaluation to compare variations of our models.Comment: ECCV201

Extrusion-Based Additive Manufacturing of the Moisture-Cured Silicone Elastomer

The extrusion-based additive manufacturing (AM) of moisture-cured silicone elastomer for complex freeform shape is studied. Due to its low elastic modulus and poor shape retaining ability during the layer-by-layer process, silicone elastomer AM is technically challenging. The experiment for extrusion of room temperature vulcanization silicone elastomer is conducted to study effects of air pressure, nozzle size and speed, layer height and distance between silicone lines on the flow rate and cross-sectional geometry of silicone elastomer AM. The COMSOLTM Multiphysics simulation using the level function to track the silicone-air interface is applied to model the silicone flow. Modeling and experimental results of the diameter and flow rate of silicone under the free flowing condition has good agreement and shows the potential for model-based guidelines for AM of silicone elastomers. Effects of the nozzle speed, layer height, and distance between two adjacent lines are investigated and demonstrate the feasibility and limitations of AM of silicone elastomer.Mechanical Engineerin

Time-bin entangled photon holes

The general concept of entangled photon holes is based on a correlated absence of photon pairs in an otherwise constant optical background. Here we consider the specialized case when this background is confined to two well-defined time bins, which allows the formation of time-bin entangled photon holes. We show that when the typical coherent state background is replaced by a true single-photon (Fock state) background, the basic time-bin entangled photon-hole state becomes equivalent to one of the time-bin entangled photon-pair states. We experimentally demonstrate these ideas using a parametric down-conversion photon-pair source, linear optics, and post-selection to violate a Bell inequality with time-bin entangled photon holes.Comment: 6 pages, 5 figure

Kinetic Inductance of Josephson Junction Arrays: Dynamic and Equilibrium Calculations

We show analytically that the inverse kinetic inductance $L^{-1}$ of an overdamped junction array at low frequencies is proportional to the admittance of an inhomogeneous equivalent impedance network. The $ij^{th}$ bond in this equivalent network has an inverse inductance $J_{ij}\cos(\theta_i^0-\theta_j^0-A_{ij})$, where $J_{ij}$ is the Josephson coupling energy of the $ij^{th}$ bond, $\theta_i^0$ is the ground-state phase of the grain $i$, and $A_{ij}$ is the usual magnetic phase factor. We use this theorem to calculate $L^{-1}$ for square arrays as large as $180\times 180$. The calculated $L^{-1}$ is in very good agreement with the low-temperature limit of the helicity modulus $\gamma$ calculated by conventional equilibrium Monte Carlo techniques. However, the finite temperature structure of $\gamma$, as a function of magnetic field, is \underline{sharper} than the zero-temperature $L^{-1}$, which shows surprisingly weak structure. In triangular arrays, the equilibrium calculation of $\gamma$ yields a series of peaks at frustrations $f = \frac{1}{2}(1-1/N)$, where $N$ is an integer $\geq 2$, consistent with experiment.Comment: 14 pages + 6 postscript figures, 3.0 REVTe