The Role of Tensor Force in Heavy-Ion Fusion Dynamics

The tensor force is implemented into the time-dependent Hartree-Fock (TDHF) theory so that both exotic and stable collision partners, as well as their dynamics in heavy-ion fusion, can be described microscopically. The role of tensor force on fusion dynamics is systematically investigated for $^{40}\mathrm{Ca}+\mathrm{^{40}Ca}$, $^{40}\mathrm{Ca}+\mathrm{^{48}Ca}$, $^{48}\mathrm{Ca}+\mathrm{^{48}Ca}$, $^{48}\mathrm{Ca}+\mathrm{^{56}Ni}$, and $^{56}\mathrm{Ni}+\mathrm{^{56}Ni}$ reactions which vary by the total number of spin-unsaturated magic numbers in target and projectile. A notable effect on fusion barriers and cross sections is observed by the inclusion of tensor force. The origin of this effect is analyzed. The influence of isoscalar and isovector tensor terms is investigated with the T$IJ$ forces. These effects of tensor force in fusion dynamics are essentially attributed to the shift of low-lying vibration states of colliding partners and nucleon transfer in the asymmetric reactions. Our calculations of above-barrier fusion cross sections also show that tensor force does not significantly affect the dynamical dissipation at near-barrier energies

Quantum metrology enhanced by the XYXY spin interaction in a generalized Tavis-Cummings model

Quantum metrology is recognized for its capability to offer high-precision estimation by utilizing quantum resources, such as quantum entanglement. Here, we propose a generalized Tavis-Cummings model by introducing the $XY$ spin interaction to explore the impact of the many-body effect on estimation precision, quantified by the quantum Fisher information (QFI). By deriving the effective description of our model, we establish a closed relationship between the QFI and the spin fluctuation induced by the $XY$ spin interaction. Based on this exact relation, we emphasize the indispensable role of the spin anisotropy in achieving the Heisenberg-scaling precision for estimating a weak magnetic field. Furthermore, we observe that the estimation precision can be enhanced by increasing the strength of the spin anisotropy. We also reveal a clear scaling transition of the QFI in the Tavis-Cummings model with the reduced Ising interaction. Our results contribute to the enrichment of metrology theory by considering many-body effects, and they also present an alternative approach to improving the estimation precision by harnessing the power provided by many-body quantum phases

Role of Phosphatidylinositol-3-Kinase Pathway in Head and Neck Squamous Cell Carcinoma

Activation of the phosphatidylinositol-3-kinase (PI3K) pathway is one of the most frequently observed molecular alterations in many human malignancies, including head and neck squamous cell carcinoma (HNSCC). A growing body of evidence demonstrates the prime importance of the PI3K pathway at each stage of tumorigenesis, that is, tumor initiation, progression, recurrence, and metastasis. Expectedly, targeting the PI3K pathway yields some promising results in both preclinical studies and clinical trials for certain cancer patients. However, there are still many questions that need to be answered, given the complexity of this pathway and the existence of its multiple feedback loops and interactions with other signaling pathways. In this paper, we will summarize recent advances in the understanding of the PI3K pathway role in human malignancies, with an emphasis on HNSCC, and discuss the clinical applications and future direction of this field