Empirical Study of Deep Learning for Text Classification in Legal Document Review

Predictive coding has been widely used in legal matters to find relevant or privileged documents in large sets of electronically stored information. It saves the time and cost significantly. Logistic Regression (LR) and Support Vector Machines (SVM) are two popular machine learning algorithms used in predictive coding. Recently, deep learning received a lot of attentions in many industries. This paper reports our preliminary studies in using deep learning in legal document review. Specifically, we conducted experiments to compare deep learning results with results obtained using a SVM algorithm on the four datasets of real legal matters. Our results showed that CNN performed better with larger volume of training dataset and should be a fit method in the text classification in legal industry.Comment: 2018 IEEE International Conference on Big Data (Big Data

The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma

<p>Abstract</p> <p>Background</p> <p>Salivary adenoid cystic carcinoma (SACC) is one of the most common malignancies of salivary gland. Recurrence or/and early metastasis is its biological properties. In SACC, neoplastic myoepithelial cells secrete proteoglycans unconventionally full of the cribriform or tubular and glandular structures of SACC. Literatures have demonstrated that extracellular matrix provided an essential microenvironment for the biological behavior of SACC. However, there is rare study of the effect of proteoglycans on the potential metastasis of SACC.</p> <p>In this study, human xylosyltransferase-I (XTLY-I) gene, which catalyzes the rate-limited step of proteoglycans biosynthesis, was knocked down by RNA interference (RNAi) to inhibit the proteoglycans biosynthesis in SACC cell line with high tendency of lung metastasis (SACC-M). The impact of down-regulated proteoglycans on the metastasis characters of SACC-M cells was analyzed and discussed. This research could provide a new idea for the clinical treatment of SACC.</p> <p>Methods</p> <p>The eukaryotic expression vector of short hairpin RNA (shRNA) targeting XTLY-I gene was constructed and transfected into SACC-M cells. A stably transfectant cell line named SACC-M-WJ4 was isolated. The XTLY-I expression was measured by real-time PCR and Western blot; the reduction of proteoglycans was measured. The invasion and metastasis of SACC-M-WJ4 cells were detected; the effect of down-regulated proteoglycans on the potential lung metastasis of nude mice was observed, respectively.</p> <p>Results</p> <p>The shRNA plasmid targeting XTLY-I gene showed powerful efficiency of RNAi. The mRNA level of target gene decreased by 86.81%, the protein level was decreased by 80.10%, respectively. The silence of XTLY-I gene resulted in the reduction of proteoglycans significantly in SACC-M-WJ4 cells. The inhibitory rate of proteoglycans was 58.17% (24 h), 66.06% (48 h), 57.91% (72 h), 59.36% (96 h), and 55.65% (120 h), respectively. The reduction of proteoglycans suppressed the adhesion, invasion and metastasis properties of SACC-M cells, and decreased the lung metastasis of SACC-M cells markedly either.</p> <p>Conclusion</p> <p>The data suggested that the silence of XTLY-I gene in SACC-M cells could suppress proteoglycans biosynthesis and secretion significantly. The reduction of proteoglycans inhibited cell adhesion, invasion and metastasis of SACC-M cells. There is a close relationship between proteoglycans and the biological behavior of SACC.</p

Exploratory Study on the Methodology of Fast Imaging of Unilateral Stroke Lesions by Electrical Impedance Asymmetry in Human Heads

Stroke has a high mortality and disability rate and should be rapidly diagnosed to improve prognosis. Diagnosing stroke is not a problem for hospitals with CT, MRI, and other imaging devices but is difficult for community hospitals without these devices. Based on the mechanism that the electrical impedance of the two hemispheres of a normal human head is basically symmetrical and a stroke can alter this symmetry, a fast electrical impedance imaging method called symmetrical electrical impedance tomography (SEIT) is proposed. In this technique, electrical impedance tomography (EIT) data measured from the undamaged craniocerebral hemisphere (CCH) is regarded as reference data for the remaining EIT data measured from the other CCH for difference imaging to identify the differences in resistivity distribution between the two CCHs. The results of SEIT imaging based on simulation data from the 2D human head finite element model and that from the physical phantom of human head verified this method in detection of unilateral stroke

A New Method to Analyze the Security of Protocol Implementations Based on Ideal Trace

The security analysis of protocols on theory level cannot guarantee the security of protocol implementations. To solve this problem, researchers have done a lot, and many achievements have been reached in this field, such as model extraction and code generation. However, the existing methods do not take the security of protocol implementations into account. In this paper, we have proposed to exploit the traces of function return values to analyze the security of protocol implementations at the source code level. Taking classic protocols into consideration, for example (like the Needham-Schroeder protocol and the Diffie-Hellman protocol, which cannot resist man-in-the-middle attacks), we have analyzed man-in-the-middle attacks during the protocol implementations and have carried out experiments. It has been shown in the experiments that our new method works well. Different from other methods of analyzing the security of protocol implementations in the literatures, our new method can avoid some flaws of program languages (like C language memory access, pointer analysis, etc.) and dynamically analyze the security of protocol implementations

Inertia matching of CNC cycloidal gear form grinding machine servo system

Reasonable ratio between the load inertia and servo motor inertia plays a decisive role for the dynamic performance and stability of the servo system, as well as the machining accuracy of the whole CNC machine. In order to improve the control performance and contour machining accuracy of the servo system of the CNC cycloidal gear form grinding machine, an optimization design method of the inertia matching for the CNC cycloidal gear form grinding machine servo system is proposed. The two-mass servo driving closed-loop PID control system is constructed, the influence of the different inertia ratios on the dynamic performance and contour errors of the servo system are deeply analyzed, and the inertia ratio is optimized to satisfied with the servo system performance requirements. Finally, the feasibility and practicability of the optimization design method of inertia matching are verified through the inertia ratio optimization grinding experiments of the cycloid gear in the CNC gear form grinding machine. This inertia matching optimization design method provides a valuable reference for the further design of CNC machine servo system

Application of the strip clear-cutting system in a running bamboo (Phyllostachys glauca McClure) forest: feasibility and sustainability assessments

IntroductionAs a renewable forest resource, bamboo plays a role in sustainable forest development. However, traditional cutting systems, selection cutting (SeC) and clear-cutting (ClC), result in an unsustainable production of bamboo forests due to labor-consuming or bamboo degradation. Recently, a strip clear-cutting (StC) was theoretically proposed to promote the sustainability of bamboo production, while little is known about its application consequence.MethodsBased on a 6-year experiment, we applied the strip clear-cutting system in a typical running bamboo (Phyllostachys glauca McClure) forest to assess its feasibility and sustainability. Using SeC and ClC as controls, we set three treatments with different strip widths (5 m, 10 m, and 20 m) for strip clear-cutting, simplified as StC-5, StC-10, and StC-20, respectively. Then, we investigated leaf physiological traits, bamboo size and productivity, population features, and economic benefits for all treatments.ResultsThe stands managed by StC had high eco-physiological activities, such as net photosynthetic rate (Pn), photosynthetic nitrogen use efficiency (PNUE), and photosynthetic phosphorus use efficiency (PPUE), and thus grew well, achieved a large diameter at breast height (DBH), and were tall. The stand biomass of StC (8.78 t hm-2 year-1) was 1.19-fold and 1.49-fold greater than that of SeC and ClC, respectively, and StC-10 and StC-20 were significantly higher than SeC or ClC (p&lt; 0.05). The income and profit increased with the increase in stand density and biomass, and StC-20 and StC-10 were significantly higher than SeC or ClC (p&lt; 0.05). Using principal components analysis and subordinate function analysis, we constructed a composite index to indicate the sustainability of bamboo forests. For the sustainability assessment, StC-10 had the highest productive sustainability (0.59 ± 0.06) and the second highest economic sustainability (0.59 ± 0.11) in all cutting treatments. StC-10 had the maximum overall sustainability, with a value of 0.53 ± 0.02, which was significantly higher than that of ClC (p&lt; 0.05).ConclusionThe results verified that StC for Phyllostachys glauca forests is feasible and sustainable as its sustainability index outweighs those of traditional cutting systems (SeC and ClC), and 10 m is the optimum distance for the strip width of StC. Our findings provide a new cutting system for managing other running bamboo forests sustainably