258 research outputs found

    Reasoning over Hierarchical Question Decomposition Tree for Explainable Question Answering

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    Explainable question answering (XQA) aims to answer a given question and provide an explanation why the answer is selected. Existing XQA methods focus on reasoning on a single knowledge source, e.g., structured knowledge bases, unstructured corpora, etc. However, integrating information from heterogeneous knowledge sources is essential to answer complex questions. In this paper, we propose to leverage question decomposing for heterogeneous knowledge integration, by breaking down a complex question into simpler ones, and selecting the appropriate knowledge source for each sub-question. To facilitate reasoning, we propose a novel two-stage XQA framework, Reasoning over Hierarchical Question Decomposition Tree (RoHT). First, we build the Hierarchical Question Decomposition Tree (HQDT) to understand the semantics of a complex question; then, we conduct probabilistic reasoning over HQDT from root to leaves recursively, to aggregate heterogeneous knowledge at different tree levels and search for a best solution considering the decomposing and answering probabilities. The experiments on complex QA datasets KQA Pro and Musique show that our framework outperforms SOTA methods significantly, demonstrating the effectiveness of leveraging question decomposing for knowledge integration and our RoHT framework.Comment: has been accepted by ACL202

    Temperature-dependent exciton-related transition energies mediated by carrier concentrations in unintentionally Al-doped ZnO films

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    The authors reported on a carrier-concentration mediation of exciton-related radiative transition energies in Al-doped ZnO films utilizing temperature-dependent (TD) photoluminescence and TD Hall-effect characterizations. The transition energies of free and donor bound excitons consistently change with the measured TD carrier concentrations. Such a carrier-concentration mediation effect can be well described from the view of heavy-doping-induced free-carrier screening and band gap renormalization effects. This study gives an important development to the currently known optical properties of ZnO materials.This research is supported by the State Key Program for Basic Research of China under Grant No. 2011CB302003, National Natural Science Foundation of China (Nos. 61025020, 60990312, and 61274058), Basic Research Program of Jiangsu Province (BK2011437), and the Priority Academic Program Development of Jiangsu Higher Education Institutions

    Thermal pretreatment of sapphire substrates prior to ZnO buffer layer growth

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    The properties of ZnO buffer layers grown via metal-organic chemical vapor deposition (MOCVD) on sapphire substrates after various thermal pretreatments are systematically investigated. High-temperature pretreatments lead to significant modifications of the sapphire surface, which result in enhanced growth nucleation and a consequent improvement of the surface morphology and quality of the ZnO layers. The evolution of the surface morphology as seen by atomic force microscopy indicates an obvious growth mode transition from three-dimensional to quasi-two-dimensional as the pretreatment temperature increases. A minimum surface roughness is obtained when the pretreatment temperature reaches 1150 °C, implying that a high-temperature pretreatment at 1150 °C or above may lead to a conversion of the surface polarity from O-face to Zn-face, similar to processes in GaN material growth via MOCVD. By analyzing the evolution of the film properties as a function of pretreatment temperature, the optimal condition has been determined to be at 1150 °C. This study indicates that a high-temperature pretreatment is crucial to grow high-quality ZnO on sapphire substrates by MOCVD.This research was supported by the State Key Program for Basic Research of China under Grant No. 2011CB302003, National Natural Science Foundation of China (Nos. 61025020, 60990312, and 61274058), Basic Research Program of Jiangsu Province (BK2011437), and the Priority Academic Program Development of Jiangsu Higher Education Institutions

    KQA Pro: A Large-Scale Dataset with Interpretable Programs and Accurate SPARQLs for Complex Question Answering over Knowledge Base

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    Complex question answering over knowledge base (Complex KBQA) is challenging because it requires various compositional reasoning capabilities, such as multi-hop inference, attribute comparison, set operation, and etc. Existing benchmarks have some shortcomings that limit the development of Complex KBQA: 1) they only provide QA pairs without explicit reasoning processes; 2) questions are either generated by templates, leading to poor diversity, or on a small scale. To this end, we introduce KQA Pro, a large-scale dataset for Complex KBQA. We define a compositional and highly-interpretable formal format, named Program, to represent the reasoning process of complex questions. We propose compositional strategies to generate questions, corresponding SPARQLs, and Programs with a small number of templates, and then paraphrase the generated questions to natural language questions (NLQ) by crowdsourcing, giving rise to around 120K diverse instances. SPARQL and Program depict two complementary solutions to answer complex questions, which can benefit a large spectrum of QA methods. Besides the QA task, KQA Pro can also serves for the semantic parsing task. As far as we know, it is currently the largest corpus of NLQ-to-SPARQL and NLQ-to-Program. We conduct extensive experiments to evaluate whether machines can learn to answer our complex questions in different cases, that is, with only QA supervision or with intermediate SPARQL/Program supervision. We find that state-of-the-art KBQA methods learnt from only QA pairs perform very poor on our dataset, implying our questions are more challenging than previous datasets. However, pretrained models learnt from our NLQ-to-SPARQL and NLQ-to-Program annotations surprisingly achieve about 90\% answering accuracy, which is even close to the human expert performance..

    OsHAC1;1 and OsHAC1;2 function as arsenate reductases and regulate arsenic accumulation

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    Rice is a major dietary source of the toxic metalloid arsenic (As). Reducing its accumulation in rice (Oryza sativa) grain is of critical importance to food safety. Rice roots take up arsenate and arsenite depending on the prevailing soil conditions. The first step of arsenate detoxification is its reduction to arsenite, but the enzyme(s) catalyzing this reaction in rice remains unknown. Here, we identify OsHAC1;1 and OsHAC1;2 as arsenate reductases in rice. OsHAC1;1 and OsHAC1;2 are able to complement an Escherichia coli mutant lacking the endogenous arsenate reductase and to reduce arsenate to arsenite. OsHAC1:1 and OsHAC1;2 are predominantly expressed in roots, with OsHAC1;1 being abundant in the epidermis, root hairs, and pericycle cells while OsHAC1;2 is abundant in the epidermis, outer layers of cortex, and endodermis cells. Expression of the two genes was induced by arsenate exposure. Knocking out OsHAC1;1 or OsHAC1;2 decreased the reduction of arsenate to arsenite in roots, reducing arsenite efflux to the external medium. Loss of arsenite efflux was also associated with increased As accumulation in shoots. Greater effects were observed in a double mutant of the two genes. In contrast, overexpression of either OsHAC1;1 or OsHAC1;2 increased arsenite efflux, reduced As accumulation, and enhanced arsenate tolerance. When grown under aerobic soil conditions, overexpression of either OsHAC1;1 or OsHAC1;2 also decreased As accumulation in rice grain, whereas grain As increased in the knockout mutants. We conclude that OsHAC1;1 and OsHAC1;2 are arsenate reductases that play an important role in restricting As accumulation in rice shoots and grain

    Higher radiation doses after partial laryngectomy may raise the incidence of pneumonia: A retrospective cohort study

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    BackgroundCurrently, studies have shown that a high dose of radiotherapy to the throat have various harmful and adverse effects on the patients’ laryngeal function, resulting in the development of pneumonia. This study aimed to explore how radiotherapy dose affected the probability of pneumonia following laryngeal cancer surgery.Materials and methodsA retrospective analysis was done on patients diagnosed with laryngeal cancer between 2010 and 2020 and were treated surgically and with postoperative radiotherapy in the same institution. This study included 108 patients in total, 51 of who were in the low-dose group and 57 of whom were in the high-dose group. Age, gender, the location of laryngeal cancer, the presence or absence of lymph node metastasis, and other demographic and clinical characteristics were collected, and the prevalence of postoperative pneumonia was compared between the two groups.ResultsThe total prevalence of postoperative pneumonia was 59.3%, but there was a significant difference between the two groups(high-dose group 71.9% VS low-dose group 45.1%; p=0.005). A total of 9.3% (10/108) of the patients had readmission due to severe pneumonia, and the rate of readmission due to pneumonia was significantly different between the two groups (high-dose group 15.8% VS low-dose group 2.0%, p=0.032). Additionally, the high-dose group’s prevalence of Dysphagia was significantly higher than the low-dose group’s. According to multivariate logistic modeling, high-dose radiation was a risk factor for pneumonia (OR=4.224, 95%CI =1.603-11.131, p=0.004).ConclusionPneumonia risk could increase with radiotherapy doses > 50 Gy in the treatment of laryngeal cancer. Therefore, we recommend that when the radiation dose surpasses 50Gy, doctors should pay particular attention to the lung health of patients with laryngeal cancer

    Evolution of Termite Symbiosis Informed by Transcriptome-Based Phylogenies

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    Termitidae comprises approximately 80% of all termite species [1] that play dominant decomposer roles in tropical ecosystems [2, 3]. Two major events during termite evolution were the loss of cellulolytic gut protozoans in the ancestor of Termitidae and the subsequent gain in the termitid subfamily Macrotermitinae of fungal symbionts cultivated externally in "combs" constructed within the nest [4, 5]. How these symbiotic transitions occurred remains unresolved. Phylogenetic analyses of mitochondrial data previously suggested that Macrotermitinae is the earliest branching termitid lineage, followed soon after by Sphaerotermitinae [6], which cultivates bacterial symbionts on combs inside its nests [7]. This has led to the hypothesis that comb building was an important evolutionary step in the loss of gut protozoa in ancestral termitids [8]. We sequenced genomes and transcriptomes of 55 termite species and reconstructed phylogenetic trees from up to 4,065 orthologous genes of 68 species. We found strong support for a novel sister-group relationship between the bacterial comb-building Sphaerotermitinae and fungus comb-building Macrotermitinae. This key finding indicates that comb building is a derived trait within Termitidae and that the creation of a comb-like "external rumen" involving bacteria or fungi may not have driven the loss of protozoa from ancestral termitids, as previously hypothesized. Instead, associations with gut prokaryotic symbionts, combined with dietary shifts from wood to other plant-based substrates, may have played a more important role in this symbiotic transition. Our phylogenetic tree provides a platform for future studies of comparative termite evolution and the evolution of symbiosis in this taxon
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