Metal-Support Interactions of Single-Atom Catalysts for Biomedical Applications

The development of single-atom catalysts (SACs) has become a rapidly growing research field. It is a critical challenge to understand the interactions between the single-atom metal active sites and the support materials. Recently, original research reports of SACs in biomedical applications have emerged in the literature, yet this topic has seldom been reviewed. Here, this review focuses on the latest advances in single-atom catalysis for biomedical applications and highlights the keys for the design of SACs, such as understanding the interactions between metals and supports and classifying various enzyme-like activities. This review helps bridge the knowledge of multiple disciplines and provides prospects regarding the development of SACs for biomedicine

Associations between types of physical activity and T2DM risk.

*<p>Model 1: Adjusted for age at interview, energy intake, smoking, alcohol consumption, education level, occupation, income level, hypertension, and family history of diabetes.</p>**<p>Model 2: As above plus BMI and WHR.</p>***<p>Analysis restricted to employed participants.</p

Associations between cigarette smoking and T2DM risk.

*<p>Model 1: Adjusted for age, energy intake, total physical activity METs, alcohol consumption, education level, occupation, income level, hypertension, and family history of diabetes.</p>**<p>Model 2: As above plus BMI and WHR.</p

Demographic characteristics of participants by T2DM status.

<p>T-tests were used for continuous variables; chi-square tests were used for categorical variables.</p