Galaxy-galaxy weak-lensing measurement from SDSS: II. host halo properties of galaxy groups

As the second paper of a series on studying galaxy-galaxy lensing signals using the Sloan Digital Sky Survey Data Release 7 (SDSS DR7), we present our measurement and modelling of the lensing signals around groups of galaxies. We divide the groups into four halo mass bins, and measure the signals around four different halo-center tracers: brightest central galaxy (BCG), luminosity-weighted center, number-weighted center and X-ray peak position. For X-ray and SDSS DR7 cross identified groups, we further split the groups into low and high X-ray emission subsamples, both of which are assigned with two halo-center tracers, BCGs and X-ray peak positions. The galaxy-galaxy lensing signals show that BCGs, among the four candidates, are the best halo-center tracers. We model the lensing signals using a combination of four contributions: off-centered NFW host halo profile, sub-halo contribution, stellar contribution, and projected 2-halo term. We sample the posterior of 5 parameters i.e., halo mass, concentration, off-centering distance, sub halo mass, and fraction of subhalos via a MCMC package using the galaxy-galaxy lensing signals. After taking into account the sampling effects (e.g. Eddington bias), we found the best fit halo masses obtained from lensing signals are quite consistent with those obtained in the group catalog based on an abundance matching method, except in the lowest mass bin. Subject headings: (cosmology:) gravitational lensing, galaxies: clusters: generalComment: 12 pages, 7 figures, submitted to Ap

A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress

<p>Abstract</p> <p>Background</p> <p>The nematode <it>Caenorhabditis elegans </it>is both sensitive and tolerant to hypoxic stress, particularly when the evolutionarily conserved hypoxia response pathway HIF-1/EGL-9/VHL is involved. Hypoxia-induced changes in the expression of a number of genes have been analyzed using whole genome microarrays in <it>C. elegans</it>, but the changes at the protein level in response to hypoxic stress still remain unclear.</p> <p>Results</p> <p>Here, we utilized a quantitative proteomic approach to evaluate changes in the expression patterns of proteins during the early response to hypoxia in <it>C. elegans</it>. Two-dimensional difference gel electrophoresis (2D-DIGE) was used to compare the proteomic maps of wild type <it>C. elegans </it>strain N2 under a 4-h hypoxia treatment (0.2% oxygen) and under normoxia (control). A subsequent analysis by MALDI-TOF-TOF-MS revealed nineteen protein spots that were differentially expressed. Nine of the protein spots were significantly upregulated, and ten were downregulated upon hypoxic stress. Three of the upregulated proteins were involved in cytoskeletal function (LEV-11, MLC-1, ACT-4), while another three upregulated (ATP-2, ATP-5, VHA-8) were ATP synthases functionally related to energy metabolism. Four ribosomal proteins (RPL-7, RPL-8, RPL-21, RPS-8) were downregulated, indicating a decrease in the level of protein translation upon hypoxic stress. The overexpression of tropomyosin (LEV-11) was further validated by Western blot. In addition, the mutant strain of <it>lev-11(x12</it>) also showed a hypoxia-sensitive phenotype in subsequent analyses, confirming the proteomic findings.</p> <p>Conclusions</p> <p>Taken together, our data suggest that altered protein expression, structural protein remodeling, and the reduction of translation might play important roles in the early response to oxygen deprivation in <it>C. elegans</it>, and this information will help broaden our knowledge on the mechanism of hypoxia response.</p

Fully Band Resolved Scattering Rate in MgB2 Revealed by Nonlinear Hall Effect and Magnetoresistance Measurements

We have measured the normal state temperature dependence of the Hall effect and magnetoresistance in epitaxial MgB2 thin films with variable disorders characterized by the residual resistance ratio RRR ranging from 4.0 to 33.3. A strong nonlinearity of the Hall effect and magnetoresistance have been found in clean samples, and they decrease gradually with the increase of disorders or temperature. By fitting the data to the theoretical model based on the Boltzmann equation and ab initio calculations for a four-band system, for the first time, we derived the scattering rates of these four bands at different temperatures and magnitude of disorders. Our method provides a unique way to derive these important parameters in multiband systems.Comment: 4 pages, 4 figure

Modified Glomerular Filtration Rate-Estimating Equations Developed in Asiatic Population for Chinese Patients with Type 2 Diabetes

Objectives. To evaluate eight modified equations developed in Asiatic populations in type 2 diabetic patients in China. Methods. A total of 209 Chinese patients with type 2 diabetes were recruited. Using the technetium—99m diethylenetriaminepentaacetic acid—glomerular filtration rate (GFR) to act as the reference, comparisons of their efficiency to estimate GFR in the subjects were made between various equations. Results. Median of difference of the Chinese equation 1 was the lowest (median of difference, 0.51 mL/min/1.73 m2). Median percent of absolute difference of the Chinese equation 2 was less than those of the other equations (26.97 versus ranged from 32.54 to 37.61 mL/min/1.73 m2, [P<0.001 for all]). Precision of the simplified reexpressed MDRD equation was the best (92.9 mL/min/1.73 m2). Accuracies of the Chinese equation 2 were greater (P<0.05 for all). There was also an improvement in chronic kidney disease (CKD) stage misclassification of the Chinese equation 2 (55.0 versus ranged from 61.2 to 64.6%, [P<0.001 for all]). However, the 30% accuracies of all the equations were less than 70%. Conclusions. Our study highlighted a limitation in the use of the above equations in the majority of Chinese diabetic subjects. A better equation is needed in order to give an accurate estimation of GFR in type 2 diabetic patients in China

Black holes regulate cold gas accretion in massive galaxies

Nearly every massive galaxy contains a supermassive black hole (BH) at its center. For decades, both theory and numerical simulations have indicated that BHs play a central role in regulating the growth and quenching of galaxies. Specifically, BH feedback by heating or blowing out the interstellar medium (ISM) serves as the groundwork for current models of massive galaxy formation. However, direct evidence for such an impact on the galaxy-wide ISM from BHs has only been found in some extreme objects. For general galaxy populations, it remains unclear whether and how BHs impact the ISM. Here based on a large sample of nearby galaxies with measurements of masses of both black holes and atomic hydrogen, the major component of cold ISM, we reveal that the atomic hydrogen content ($f_{\rm HI} = M_{\rm HI}/M_{\star}$) is tightly and anti-correlated with black hole mass ($M_{\rm BH}$) with $f_{\rm HI} \propto M^{-\alpha}_{\rm BH}$ ($\alpha \sim 0.5-0.6$). This correlation is valid across five orders of magnitude in $M_{\rm BH}$. Once this correlation is taken into account, $f_{\rm HI}$ loses dependence on other galactic parameters, demonstrating that $M_{\rm BH}$ serves as the primary driver of $f_{\rm HI}$. These findings provide critical evidence for how the accumulated energy from BH accretion impacts galaxy-wide ISM, representing a crucial step forward in our understanding on the role of BHs in regulating the growth and quenching of massive galaxies.Comment: 24 pages, 7 figures. Submitted to Natur

Reliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens

<p>Abstract</p> <p>Background</p> <p>The Ahringer <it>C. elegans </it>RNAi feeding library prepared by cloning genomic DNA fragments has been widely used in genome-wide analysis of gene function. However, the library has not been thoroughly validated by direct sequencing, and there are potential errors, including: 1) mis-annotation (the clone with the retired gene name should be remapped to the actual target gene); 2) nonspecific PCR amplification; 3) cross-RNAi; 4) mis-operation such as sample loading error, <it>etc</it>.</p> <p>Results</p> <p>Here we performed a reliability analysis on the Ahringer <it>C. elegans </it>RNAi feeding library, which contains 16,256 bacterial strains, using a bioinformatics approach. Results demonstrated that most (98.3%) of the bacterial strains in the library are reliable. However, we also found that 2,851 (17.54%) bacterial strains need to be re-annotated even they are reliable. Most of these bacterial strains are the clones having the retired gene names. Besides, 28 strains are grouped into unreliable category and 226 strains are marginal because of probably expressing unrelated double-stranded RNAs (dsRNAs). The accuracy of the prediction was further confirmed by direct sequencing analysis of 496 bacterial strains. Finally, a freely accessible database named CelRNAi (<url>http://biocompute.bmi.ac.cn/CelRNAi/</url>) was developed as a valuable complement resource for the feeding RNAi library by providing the predicted information on all bacterial strains. Moreover, submission of the direct sequencing result or any other annotations for the bacterial strains to the database are allowed and will be integrated into the CelRNAi database to improve the accuracy of the library. In addition, we provide five candidate primer sets for each of the unreliable and marginal bacterial strains for users to construct an alternative vector for their own RNAi studies.</p> <p>Conclusions</p> <p>Because of the potential unreliability of the Ahringer <it>C. elegans </it>RNAi feeding library, we strongly suggest the user examine the reliability information of the bacterial strains in the CelRNAi database before performing RNAi experiments, as well as the post-RNAi experiment analysis.</p

Corrigendum to: The TianQin project: current progress on science and technology

In the originally published version, this manuscript included an error related to indicating the corresponding author within the author list. This has now been corrected online to reflect the fact that author Jun Luo is the corresponding author of the article

College Students' Behavior Initiative, Psychological Availability, and Innovation and Entrepreneurship: The Mediating Effect of Interest Orientation

The features of college students’ initiative character and psychological availability can generate great influence on their Innovative and Entrepreneurship (I&amp;E). Relevant existing studies paid insufficient attention on the interest orientation management of college students’ I&amp;E from the perspective of I&amp;E education, and few of them viewed the problems of the behavior initiative and psychological availability of college students’ I&amp;E from the perspective of individual student. To fill in these research blanks, this paper aims to analyze the relationship among behavior initiative, psychological availability, and I&amp;E interest orientation of college students. At first, based on the evaluation data of the behavior initiative and psychological availability features of college students’ I&amp;E, tags of their I&amp;E behavior were created, and the behavior preferences of their I&amp;E were predicted based on the machine learning algorithm. Then, the prediction results of I&amp;E interest were tested using the mediating effect method, and it’s found that when behavior initiative and psychological availability features affect college students’ I&amp;E performance, interest orientation plays a mediating role in the process. The experiment verified the effectiveness of the proposed prediction model and gave the analysis results of the mediating effect