Thymoma with Myasthenia Gravis in Adolescent

Thymomas are exceedingly rare in the first 20 years of life, Thymic lesions comprise approximately 2–3% of all pediatric mediastinal tumors and include thymic cysts, hyperplasia, carcinoma, and thymomas. Fewer than 30 cases in children have been described in the literature. Thymomas in adults are commonly associated with other diseases, the most frequent being myasthenia gravis. However, this association has been rarely reported in childhood. These tumors are typically aggressive, with poor outcomes. We report a case of thymoma associated with myasthenia gravis in a 16-year-old girl and review the literature

Ganglioneuroma Always A Histopathological Diagnosis

Neuroblastoma, ganglioneuroblastoma and ganglioneuroma arise from sympathetic tissue in the neck, posterior mediastinum, adrenal gland, retroperitoneum and pelvis Ganglioneuromas are commonly seen in childhood. They are highly differentiated benign tumors and are compatible with long-term disease free survival. Retroperitoneal localization is relatively frequent for these tumors. Due to its rarity and lack of specific radiological findings diagnosis is always postoperative. Here, we present a case of Retroperitoneal ganglioneuroma which was undiagnosed before surgery

Primary Fallopian Tube Carcinoma

Primary Fallopian Tube Carcinoma (PFTC) is rare and accounts for about 0.3% of all gynecologic cancers. Less than 1500 cases have been reported in the literature. It arises in postmenopausal women and typically presents with abdominal pelvic pain, vaginal bleeding and watery discharge. However, a correct diagnosis is rarely achieved preoperative, and in many cases, the diagnosis is made after incidental surgery for unrelated conditions commonly being ovarian carcinoma . Compared with ovarian carcinoma, PFTC more often presents at early stages, but it has a worse prognosis. PFTC is usually managed in the same manner as ovarian cancer. We report a case of Left PFTC that presented as Left ovarian mass, and we briefly review the literature

Solitary Pancreatic Metastasis from Renal Cell Carcinoma: A Case Report from India with a Review of Literature

ABSTRACT: Metastatic cancer to the pancreas accounts for less than 2% of all pancreatic malignancies, with renal cell carcinoma being the predominant type. We report the case of an elderly patient detected with a solitary lesion in the head of the pancreas, 6 years after a nephrectomy for renal cell carcinoma. The patient underwent a pancreaticoduodenectomy for the same. A review of literature showed isolated pancreatic metastasis to be rare, ranging from 0.5 to 3%. Patients are usually asymptomatic, unless the tumor enlarges. Spread usually takes place by the hematogenous route or via lymphatics, direct spread being very unusual. Surgical resection seems to be the standard of care for isolated metastasis from renal cell carcinoma as the other modalities of treatment seem unresponsive. Typically, patients undergo a pancreaticoduodenectomy or distal pancreatectomy depending on the location of the tumor. Atypical resections are done in certain situations. Surgery is carried out in favourable candidates and a thorough evaluation needs to be done intraoperatively for multiple metastases. Histology revealed a metastatic renal cell carcinoma confirmed on immunohistochemistry. All margins were free of tumor without lymphnodal involvement. Eight months after the surgery the patient is doing well. As compared to primary pancreatic cancer, metastasis from renal cell carcinoma has a higher resectability rate. Solitary metastasis to the pancreas has a good prognosis especially in renal cell carcinoma, with a 5 years survival rate of 43 to 88%.KEYWORDS: Renal Cell Carcinoma; Pancreatic Metastasis; PancreaticoduodenectomyInternet Journal of Medical Update 2012 January;7(1):62-

Effect of a plant versus animal based diet on lipid profile of yoga practicing medical students: a pilot study

Background: Foods play an important role in human health. An excess accumulation of cholesterol in the body is one of the main causes of cardio vascular disease, hypertension, type 2 diabetes mellitus, dyslipidemia and mortality. In the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat gastrointestinal diseases. The present study was designed to discuss changes in blood cholesterol levels after the consumption of animal based (non vegetarian) and plant based (vegetarian) food on yoga practising medical students.Methods: Of 81 subjects, a total of 60 subjects within the age group 18 to 22 years were selected for the study and were divided into two groups, non-vegetarian diet group (group A; n=30) and vegetarian diet group (group B; n=30). Subjects in the group A were given a non vegetarian diet and group B a vegetarian diet for a period of 10 days. Assessments were done at baseline and after 10 days.Results: There were no statistically significant changes seen in the lipid profiles of group B and group A after the application of a paired t test. In this study the mean value of total cholesterol, serum triglyceride, serum LDL and serum VLDL were found to be slightly higher in vegetarian group than the non-vegetarian group. Mean value of serum HDL was found to be higher in non-vegetarian group than the vegetarian.Conclusions: The present study concludes that there are more changes in the pre and post lipid profile assessments of the vegetarian group in comparison to the non-vegetarian group

ASSOCIATION BETWEEN THE WEIGHT LOSS AND ANXIETY, DEPRESSION AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY: A NEED FOR PRE-DISCHARGED COUNSELING

Objectives: To see the association between weight loss and anxiety, depression after percutaneous transluminal coronary angioplasty (PTCA) for coronary artery disease patients. (1) To see the severity of anxiety and depression 1 month after PTCA, (2) to evaluate the relationship between the weight changes and major adverse cardiac events (MACE) in 1 month follow-up.Methods: A total 1001 patients who underwent PTCA for acute coronary syndrome and coronary heart disease were included. Data were collected at baseline and 1 month after PTCA. A validated Euro 5Q-5D-5L questionnaire was used to assess the level of anxiety and depression. Chi-square test was applied to find out the association between weight loss status and anxiety, depression.Results: There was a significant decrease in mean weight 1 month after coronary angioplasty (64.18±11.022 vs. 61.96±11.17, p<0.001). No association was observed between weight loss status and anxiety, depression in PTCA patients (p=0.5) and there is no significant association between weight changes and MACE 1 month after PTCA (p=0.92).Conclusion: Data show that anxiety and depression were observed in 64.9% of the study population after coronary angioplasty but anxiety and depression are not associated with weight loss after PTCA. Loss of weight may be due to the modified post angioplasty lifestyles such as adherent to Mediterranean diet, physical exercise, cessation of smoking, optimum control of blood pressure, blood sugar, and blood cholesterol along with prescribed medications. Anxiety and depression may turn into chronic stage if not treated wisely could lead to significant MACE. Proper pre-hospital discharge counseling is necessary for all post PTCA patients to sustain their quality of life

Stereo Acoustic Perception based on Real Time Video Acquisition for Navigational Assistance

A smart navigation system (an Electronic Travel Aid) based on an object detection mechanism has been designed to detect the presence of obstacles that immediately impede the path, by means of real time video processing. The algorithm can be used for any general purpose navigational aid. This paper is discussed, keeping in mind the navigation of the visually impaired, and is not limited to the same. A video camera feeds images of the surroundings to a Da- Vinci Digital Media Processor, DM642, which works on the video, frame by frame. The processor carries out image processing techniques whose result contains information about the object in terms of image pixels. The algorithm aims to select the object which, among all others, poses maximum threat to the navigation. A database containing a total of three sounds is constructed. Hence, each image translates to a beep, where every beep informs the navigator of the obstacles directly in front of him. This paper implements an algorithm that is more efficient as compared to its predecessors.Comment: 12 pages, 8 figures, 1 table, SIPM-2012, pp. 97-108, 2012; http://airccj.org/CSCP/vol2/csit2311.pd

N-(4-Chloro-2-methyl­phen­yl)maleamic acid

In the mol­ecular structure of the title compound, C11H10ClNO3, the conformation of the N—H bond in the amide segment is syn to the ortho-methyl group in the phenyl ring. The C=O and O—H bonds of the acid group are in the relatively rare anti position with respect to each other. This is an obvious consequence of the hydrogen bond donated to the amide carbonyl group. The central oxobutenoic acid core C(=O)—C=C—C—OH is twisted by 31.65 (6)° out of the plane of the 4-chloro-2-methyl­phenyl ring. An intra­molecular O—H⋯O hydrogen bond occurs. In the crystal, N—H⋯O hydrogen bonds link the mol­ecules into infinite chains running along the a axis

N-(2-Chloro-4-nitro­phen­yl)maleamic acid monohydrate

The title compound, C10H7ClN2O5·H2O, crystallizes with a half-mol­ecule each of N-(2-chloro-4-nitro­phen­yl)maleamic acid (located on a mirror plane) and water (located on a twofold rotation axis) in the asymmetric unit. The main mol­ecule is planar by symmetry and its conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond. In the crystal, N—H⋯O and O—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network

Impact of Patient Counseling and Socioeconomic Factors on Initiation of Rehabilitation Program in Spinal Cord Injury Patients Presenting to a Tertiary Spine Unit in India

Study Design Prospective case series. Purpose This study aimed to investigate the impact of education, financial income, occupation, and patient counseling on the timing of enrolment in a spinal cord injury (SCI) rehabilitation program. Overview of Literature A rehabilitation program following SCI is essential to improve functional outcomes. Socioeconomic factors can affect the timing of enrolment to a rehabilitation program. Literature on the effects of socioeconomic factors among patients with SCI in the Indian scenario is limited. Methods A prospective, consecutive analysis of patients with SCI was performed with 1-year follow-up. Assessment of the timing of enrolment to a rehabilitation program was performed using the modified Kuppuswamy socioeconomic scores (MKSS). Patients admitted to the SCI unit (group A), underwent intensive individual, group, and family counseling sessions to encourage early enrolment into a rehabilitation program. Patients presenting directly for rehabilitation (group B) were analyzed for comparison. Results A total of 153 patients were recruited. Group A was composed of 122 patients who started the rehabilitation program after a mean of 28 days, compared with a mean of 149 days for 31 patients in group B. In group A, 104 patients (85%; mean MKSS, 14.02) and 18 patients (15%; mean MKSS, 15.61) enrolled for rehabilitation 0.05). Conclusions Early patient counseling in the acute care unit helps in the early enrolment of patients with poor socioeconomic demographic profile to a rehabilitation program