238 research outputs found
Acute and Chronic Bone Marker and Endocrine Responses to Resistance Exercise With and Without Blood Flow Restriction in Young Men
In this study, we compared acute and chronic bone marker and hormone responses to 6 weeks of low intensity (20% 1RM) blood flow restriction (BFR20) resistance training to high intensity (70% 1RM) traditional resistance training (TR70) and moderate intensity (45% 1RM) traditional resistance training (TR45) in young men (18–35 years). Participants were randomized to one of the training groups or to a control group (CON). The following training programs were performed 3 days per week for 6 weeks for knee extension and knee flexion exercises: BFR20, 20%1RM, 4 sets (30, 15, 15, 15 reps) wearing blood flow restriction cuffs around the proximal thighs; TR70, 70% 1RM 3 sets 10 reps; and TR45, 45% 1RM 3 sets 15 reps. Muscle strength and thigh cross-sectional area were assessed at baseline, between week 3 and 6 of training. Acute bone marker (Bone ALP, CTX-I) and hormone (testosterone, IGF-1, IGFBP-3, cortisol) responses were assessed at weeks 1 and 6, with blood collection done in the morning after an overnight fast. The main findings were that the acute bone formation marker (Bone ALP) showed significant changes for TR70 and BFR20 but there was no difference between weeks 1 and 6. TR70 had acute increases in testosterone, IGF-1, and IGFBP-3 (weeks 1 and 6). BFR20 had significant acute increases in testosterone (weeks 1 and 6) and in IGF-1 at week 6, while TR45 had significant acute increases in testosterone (week 1), IGF-1 (week 6), and IGFBP-3 (week 6). Strength and muscle size gains were similar for the training groups. In conclusion, low intensity BFR resistance training was effective for stimulating acute bone formation marker and hormone responses, although TR70 showed the more consistent hormone responses than the other training groups
Expanding attributable fraction applications to outcomes wholly attributable to a risk factor
The problem central to this document is the estimation of change in disease attributable to an epidemiological exposure variable that stems from a change in the distribution of that variable. We require that both disease and exposure are quantifiable as real numbers, and then ask how to estimate the fraction of disease attributable to exposure, producing the general attributable fraction methodology. After the mathematical framework is in place, we explore the implications of a disease that is wholly attributable to a given risk factor, demonstrate why standard applications of the attributable fractions do not extend, and present general methodological considerations for this case. Finally, we demonstrate the methodology using the example of alcoholic psychoses
Acute and Chronic Bone Marker and Endocrine Responses to Resistance Exercise With and Without Blood Flow Restriction in Young Men
In this study, we compared acute and chronic bone marker and hormone responses to 6 weeks of low intensity (20% 1RM) blood flow restriction (BFR20) resistance training to high intensity (70% 1RM) traditional resistance training (TR70) and moderate intensity (45% 1RM) traditional resistance training (TR45) in young men (18–35 years). Participants were randomized to one of the training groups or to a control group (CON). The following training programs were performed 3 days per week for 6 weeks for knee extension and knee flexion exercises: BFR20, 20%1RM, 4 sets (30, 15, 15, 15 reps) wearing blood flow restriction cuffs around the proximal thighs; TR70, 70% 1RM 3 sets 10 reps; and TR45, 45% 1RM 3 sets 15 reps. Muscle strength and thigh cross-sectional area were assessed at baseline, between week 3 and 6 of training. Acute bone marker (Bone ALP, CTX-I) and hormone (testosterone, IGF-1, IGFBP-3, cortisol) responses were assessed at weeks 1 and 6, with blood collection done in the morning after an overnight fast. The main findings were that the acute bone formation marker (Bone ALP) showed significant changes for TR70 and BFR20 but there was no difference between weeks 1 and 6. TR70 had acute increases in testosterone, IGF-1, and IGFBP-3 (weeks 1 and 6). BFR20 had significant acute increases in testosterone (weeks 1 and 6) and in IGF-1 at week 6, while TR45 had significant acute increases in testosterone (week 1), IGF-1 (week 6), and IGFBP-3 (week 6). Strength and muscle size gains were similar for the training groups. In conclusion, low intensity BFR resistance training was effective for stimulating acute bone formation marker and hormone responses, although TR70 showed the more consistent hormone responses than the other training groups.This study was funded in part by a grant from the International Society for KAATSU Training Research awarded to MB (PI) and DB (Co-PI). Financial support was provided by the University of Oklahoma Libraries’ Open Access Fund.Ye
Associations between pQCT-based fat and muscle area and density and DXA-based total and leg soft tissue mass in healthy women and men
Peripheral Quantitative Computed Tomography (pQCT) can be used for muscle and fat area and density assessments. These may independently influence muscle and fat mass measurements from Dual Energy X-ray Absorptiometry (DXA).
Objective: To determine associations between pQCT-derived soft tissue density and area measures and DXA-derived soft tissue mass.
Methods: Linear regression models were developed based on BMI and calf fat and muscle cross-sectional area (FCSA and MCSA) and density measured by pQCT in healthy women (n=76) and men (n=82) aged 20-59 years. Independent variables for these models were leg and total bone-free lean mass (BFLM) and fat mass (FM) measured by DXA.
Results:Sex differences (p
Conclusion: Calf muscle and fat area and density independently predict lean and fat tissue mass
Effective Action for High-Energy Scattering in Gravity
The multi-Regge effective action is derived directly from the linearized
gravity action. After excluding the redundant field components we separate the
fields into momentum modes and integrate over modes which correspond neither to
the kinematics of scattering nor to the one of exchanged particles. The
effective vertices of scattering and of particle production are obtained as
sums of the contributions from the triple and quartic interaction terms and the
fields in the effective action are defined in terms of the two physical
components of the metric fluctuation.Comment: 15 pages, LATE
The Abelian Topological Mass Mechanism From Dimensional Reduction
We show that the abelian topological mass mechanism in four dimensions,
described by the Cremmer-Sherk action, can be obtained from dimensional
reduction in five dimensions. Starting from a gauge invariant action in five
dimensions, where the dual equivalence between a massless vector field and a
massless second-rank antisymmetric field in five dimensions is established, the
dimensional reduction is performed keeping only one massive mode. Furthermore,
the Kalb-Ramond action and the Stuckelberger formulation for massive spin-1 are
recovered.Comment: Three references added, 6 pages, late
Dividing the waters: An empirical analysis of interstate compact allocation of transboundary rivers
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95529/1/wrcr12841.pd
Dark Matter Gravitational Interactions
We argue that the conjectured dark mater in the Universe may be endowed with
a new kind of gravitational charge that couples to a short range gravitational
interaction mediated by a massive vector field. A model is constructed that
assimilates this concept into ideas of current inflationary cosmology. The
model is also consistent with the observed behaviour of galactic rotation
curves according to Newtonian dynamics. The essential idea is that stars
composed of ordinary (as opposed to dark matter) experience Newtonian forces
due to the presence of an all pervading background of massive gravitationally
charged cold dark matter. The novel gravitational interactions are predicted to
have a significant influence on pre-inflationary cosmology. The precise details
depend on the nature of a gravitational Proca interaction and the description
of matter. A gravitational Proca field configuration that gives rise to
attractive forces between dark matter charges of like polarity exhibits
homogeneous isotropic eternal cosmologies that are free of cosmological
curvature singularities thus eliminating the horizon problem associated with
the standard big-bang scenario. Such solutions do however admit dense hot
pre-inflationary epochs each with a characteristic scale factor that may be
correlated with the dark matter density in the current era of expansion. The
model is based on a theory in which a modification of Einsteinian gravity at
very short distances can be expressed in terms of the gradient of the Einstein
metric and the torsion of a non-Riemannian connection on the bundle of linear
frames over spacetime. Indeed we demonstrate that the genesis of the model
resides in a remarkable simplification that occurs when one analyses the
variational equations associated with a broad class of non-Riemannian actions.Comment: 40 pages, 4 Postscript figure
Belga B-trees
We revisit self-adjusting external memory tree data structures, which combine
the optimal (and practical) worst-case I/O performances of B-trees, while
adapting to the online distribution of queries. Our approach is analogous to
undergoing efforts in the BST model, where Tango Trees (Demaine et al. 2007)
were shown to be -competitive with the runtime of the best
offline binary search tree on every sequence of searches. Here we formalize the
B-Tree model as a natural generalization of the BST model. We prove lower
bounds for the B-Tree model, and introduce a B-Tree model data structure, the
Belga B-tree, that executes any sequence of searches within a
factor of the best offline B-tree model algorithm, provided .
We also show how to transform any static BST into a static B-tree which is
faster by a factor; the transformation is randomized and we
show that randomization is necessary to obtain any significant speedup
Pseudoclassical theories of Majorana, Weyl and Majorana--Weyl particles
A pseudoclassical theories of Majorana, Weyl and Majorana--Weyl particles in
the space--time dimensions are constructed. The canonical quantization
of these theories is carried out and as a result we obtain the quantum
mechanical description of neutral particle in , Weyl particle in
and neutral Weyl particle in . In dimensional
space--time the description of the neutral particle coincides with the field
theoretical description of the Majorana particle in the Foldy--Wouthuysen
representation. In dimensions the neutral Weyl particle coincides with
the Majorana--Weyl particle in the Foldy--Wouthuysen representation.Comment: LATEX, 17 pages, no figure
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