Inland thinning of the Amundsen Sea sector, West Antarctica

[1] Together with the Pine Island glacier (PIG), the Thwaites (TG) and Smith (SG) glaciers are the principal drainage systems of the Amundsen Sea (AS) sector of Western Antarctica. Here we use satellite radar altimetry and interferometry to show that a rapid thinning of ice has occurred within the fastest flowing sections of all AS outlet glaciers. The pattern of thinning extends to distances greater than 150 km inland. Between 1991 and 2001, the TG and SG thinned by more than 25 and 45 m at their grounding lines, and a total of 154 +/- 16 km(3) of ice (or 0.43 mm of eustatic sea level rise) was lost from the AS sector glaciers to the ocean. We show that the thickness changes may have caused the PIG, TG, and SG to retreat inland by over 8, 4, and 7 km respectively, in line with independent estimates of grounding line migration

Lithographic technology for microwave integrated circuits

Conductive lithographic films (CLFs) have been developed primarily as substitutes for resin/laminate boards, which share properties with the metallisation patterns used in planar microwave integrated circuits (MICs). The authors examine the microwave properties of the films and show that, although the losses are greater, they have potential as an alternative to the traditional manufacturing process of MICs

Spatial and temporal evolution of Pine Island Glacier thinning, 1995-2006

We use ERS-2 and ENVISAT satellite radar altimetry to examine spatial and temporal changes in the rate of thinning of the Pine Island Glacier, West Antarctica, during the period 1995 to 2006. We show that the pattern of thinning has both accelerated and spread inland to encompass tributaries flowing into the central trunk of the glacier. Within the 5,400 km(2) central trunk, the average rate of volume loss quadrupled from 2.6 +/- 0.3 km(3) yr(-1) in 1995 to 10.1 +/- 0.3 km(3) yr(-1) in 2006. The region of lightly grounded ice at the glacier terminus is extending upstream, and the changes inland are consistent with the effects of a prolonged disturbance to the ice flow, such as the effects of ocean- driven melting. If the acceleration continues at its present rate, the main trunk of PIG will be afloat within some 100 years, six times sooner than anticipated. Citation: Wingham, D.J., D.W. Wallis, and A. Shepherd (2009), Spatial and temporal evolution of Pine Island Glacier thinning, 1995-2006, Geophys. Res. Lett., 36, L17501, doi: 10.1029/2009GL039126

Entanglement cost of generalised measurements

Bipartite entanglement is one of the fundamental quantifiable resources of quantum information theory. We propose a new application of this resource to the theory of quantum measurements. According to Naimark's theorem any rank 1 generalised measurement (POVM) M may be represented as a von Neumann measurement in an extended (tensor product) space of the system plus ancilla. By considering a suitable average of the entanglements of these measurement directions and minimising over all Naimark extensions, we define a notion of entanglement cost E_min(M) of M. We give a constructive means of characterising all Naimark extensions of a given POVM. We identify various classes of POVMs with zero and non-zero cost and explicitly characterise all POVMs in 2 dimensions having zero cost. We prove a constant upper bound on the entanglement cost of any POVM in any dimension. Hence the asymptotic entanglement cost (i.e. the large n limit of the cost of n applications of M, divided by n) is zero for all POVMs. The trine measurement is defined by three rank 1 elements, with directions symmetrically placed around a great circle on the Bloch sphere. We give an analytic expression for its entanglement cost. Defining a normalised cost of any d-dimensional POVM by E_min(M)/log(d), we show (using a combination of analytic and numerical techniques) that the trine measurement is more costly than any other POVM with d>2, or with d=2 and ancilla dimension 2. This strongly suggests that the trine measurement is the most costly of all POVMs.Comment: 20 pages, plain late

The Incidence of Retinoblastoma in South Africa: Findings from the South African National Cancer Registry (2004-2018)

Purpose: To determine the frequency and incidence rate of retinoblastoma in children in South Africa from 2004 to 2018. Methods: Incident cases of histologically diagnosed retinoblastoma were identified from the South African National Cancer Registry. Crude incidence rates were calculated using national population data on children <15 years and live births. Incidence rates were stratified and compared by age, sex and population group. Direct age-standardised incidence rates and comparative incidence ratios were calculated. Results: The overall age-standardised incidence rate for children <15 years was 3.3 per million or 1 per 21 641 live births. Age-specific rates for children aged 0–4, 5–9 and 10–14 years were 7.7, 0.8 and 0.2 per million, respectively. There was no difference in incidence rates by sex. White children had a significantly higher incidence rate compared to other population groups, but this finding may be due to systemic biases introduced by access to healthcare in South Africa or study methodology. Conclusion: This is the largest study to provide population-based, histologically confirmed national estimates of retinoblastoma incidence from an African nation to date and affirms the need for highquality cancer registries across the African continent

Effects of Photobiomodulation Therapy on Regulation of Myogenic Regulatory Factor mRNA Expression In Vivo: A Systematic Review

Non-invasive promotion of myogenic regulatory factors (MRFs), through photobiomodulation therapy (PBMT), may be a viable method of facilitating skeletal muscle regeneration post-injury, given the importance of MRF in skeletal muscle regeneration. The aim of this systematic review was to collate current evidence, identifying key themes and changes in expression of MRF in in vivo models. Web of Science, PubMed, Scopus and Cochrane databases were systematically searched and identified 1459 studies, of which 10 met the inclusion criteria. Myogenic determination factor was most consistently regulated in response to PBMT treatment, and the expression of remaining MRFs was heterogenous. All studies exhibited a high risk of bias, primarily due to lack of blinding in PBMT application and MRF analysis. Our review suggests that the current evidence base for MRF expression from PBMT is highly variable. Future research should focus on developing a robust methodology for determining the effect of laser therapy on MRF expression, as well as long-term assessment of skeletal muscle regeneration

High-density geometric morphometric analysis of intraspecific cranial integration in the barred grass snake (Natrix helvetica) and green anole (Anolis carolinensis)

How do phenotypic associations intrinsic to an organism, such as developmental and mechanical processes, direct morphological evolution? Comparisons of intraspecific and clade-wide patterns of phenotypic covariation could inform how population-level trends ultimately dictate macroevolutionary changes. However, most studies have focused on analyzing integration and modularity either at macroevolutionary or intraspecific levels, without a shared analytical framework unifying these temporal scales. In this study, we investigate the intraspecific patterns of cranial integration in two squamate species: Natrix helvetica and Anolis carolinensis. We analyze their cranial integration patterns using the same high-density 3-D geometric morphometric approach used in a prior squamate-wide evolutionary study. Our results indicate that Natrix and Anolis exhibit shared intraspecific cranial integration patterns, with some differences, including a more integrated rostrum in the latter. Notably, these differences in intraspecific patterns correspond to their respective interspecific patterns in snakes and lizards, with few exceptions. These results suggest that interspecific patterns of cranial integration reflect intraspecific patterns. Hence, our study suggests that the phenotypic associations that direct morphological variation within species extend across micro- and macroevolutionary levels, bridging these two scales

Achieving quantum supremacy with sparse and noisy commuting quantum computations

The class of commuting quantum circuits known as IQP (instantaneous quantum polynomial-time) has been shown to be hard to simulate classically, assuming certain complexity-theoretic conjectures. Here we study the power of IQP circuits in the presence of physically motivated constraints. First, we show that there is a family of sparse IQP circuits that can be implemented on a square lattice of n qubits in depth O(sqrt(n) log n), and which is likely hard to simulate classically. Next, we show that, if an arbitrarily small constant amount of noise is applied to each qubit at the end of any IQP circuit whose output probability distribution is sufficiently anticoncentrated, there is a polynomial-time classical algorithm that simulates sampling from the resulting distribution, up to constant accuracy in total variation distance. However, we show that purely classical error-correction techniques can be used to design IQP circuits which remain hard to simulate classically, even in the presence of arbitrary amounts of noise of this form. These results demonstrate the challenges faced by experiments designed to demonstrate quantum supremacy over classical computation, and how these challenges can be overcome.Comment: 23 pages, 1 figure; v4: uses standard journal styl