12 research outputs found
High-Efficiency Co/Co<sub><i>x</i></sub>S<sub><i>y</i></sub>@S,N-Codoped Porous Carbon Electrocatalysts Fabricated from Controllably Grown Sulfur- and Nitrogen-Including Cobalt-Based MOFs for Rechargeable ZincāAir Batteries
Developing bifunctional
oxygen electrocatalysts with superior catalytic activities of oxygen
reduction reaction (ORR) and oxygen revolution reaction (OER) is crucial
to their practical energy storage and conversion applications. In
this work, we report the fabrication of Co/Co<sub><i>x</i></sub>S<sub><i>y</i></sub>@S,N-codoped porous carbon structures
with various morphologies, specific surface areas, and pore structures,
derived from controllably grown Co-based metalāorganic frameworks
with S- and N-containing organic ligands (thiophene-2,5-dicarboxylate,
Tdc; and 4,4ā²-bipyridine, bpy) utilizing solvent effect (<i>e.g.</i>, water and methanol) under room temperature and hydrothermal
conditions. The results demonstrate that Co/Co<sub><i>x</i></sub>S<sub><i>y</i></sub>@S,N-codoped carbon fibers fabricated
at a pyrolytic temperature of 800 Ā°C (Co/Co<sub><i>x</i></sub>S<sub><i>y</i></sub>@SNCF-800) from Co-MOFs fibers
fabricated in methanol under hydrothermal conditions as electrocatalysts
exhibit superior bifunctional ORR and OER activities in alkaline media,
endowing them as air cathodic catalysts in rechargeable zincāair
batteries with high power density and good durability
Dual-Core Fe<sub>2</sub>O<sub>3</sub>@Carbon Structure Derived from Hydrothermal Carbonization of Chitosan as a Highly Efficient Material for Selective Adsorption
A dual-core
Fe<sub>2</sub>O<sub>3</sub>@carbon structure was prepared
by a hydrothermal treatment of iron salt and chitosan (CS) solution.
The structure exhibits microsphere-like (ā¼850 nm in size) morphology
with dual cores at two ends. The existence of CS plays an important
role in the formation of the dual-coreāshell structure. The
unique structure was investigated to be a CS adsorption, and subsequent
carbonization induced a selective etching process. Further, the special
structure was proven to be a highly efficient material for selective
adsorption. The dual-core structure facilitates the exposure of the
Fe<sub>2</sub>O<sub>3</sub> surface, and the carbonaceous shell gives
plenty of functional groups for selective adsorption. More importantly,
the selectivity was highly dependent on pH values. It was found that
the adsorbent showed higher adsorption selectivity toward CrĀ(VI) at
lower pH values, while the selectivity transferred toward CuĀ(II) at
higher pH values by adsorption of CuĀ(II) and CrĀ(VI) in single-component
solutions. In binary-component solution, the dual-core Fe<sub>2</sub>O<sub>3</sub>@C structure revealed adsorption selectivity for CrĀ(VI),
with the highest separator factor [Ī±<sub>Cu(II)</sub><sup>Cr(VI)</sup>] = 1162, due to the strong electrostatic
adsorption-coupled reduction interaction induced by the special structure
of the adsorbent. This work not only gives deep insights into the
understanding of the formation of the dual-core structure but also
supplies a novel adsorbent with selective adsorption properties for
water treatment
Analysis of migration and invasion of CpG-ODN treated HB cells.
<p>(<b>A</b>) Evaluation of cell migration by scratch wound healing assay: Cells were allowed to migrate with and without 0.8 Ī¼M CpG-ODN. Cell migration into the wound surface was then monitored by microscopy after 24 h of the CpG-ODN treatment and reported as the width of remaining wounded area relative to the initial wound area. (<b>B</b>)Evaluation of cell invasion by transwell assay. Representative photomicrographs of the membrane-associated cells (jacinth part) were assayed by Eosin staining (Ć400). (<b>C</b>)Graphical representation of scratch wound assay. The average distance of cell invasion was significantly greater in the CpG-ODN treated sample. **P<0.01. (<b>D</b>)Semi-quantitative analysis of the stimulate-invasion effects of CpG-ODN on HB cells. ā% of controlā denotes the mean number of the cells expressed as a proportion of the control group and the average of three independent experiments Ā± S.D. **p<0.01, compared with the lane 2; <sup>ā
</sup>p<0.05, compared with the lane 3. (<b>E</b>)Colorimetric analysis of CpG-ODN modulation of HB cell invasiveness with different concentrations (0ā¼0.8 Ī¼M) for 48 h by the CytoSelect cell invasion assay. *p<0.05; **p<0.01, compared with lane 1.</p
Forest plots of association between cyclin D1 overexpression with poor OS in OSCC.
<p>Forest plots of association between cyclin D1 overexpression with poor OS in OSCC.</p
Characteristics of the included studies in this meta-analysis.
<p>M/F: Male/Female; NA: not available.</p
Effect of CpG-ODN on NF- ĪŗB and AP-1 activity.
<p>(<b>A</b>) Effects of CpG-ODN on the expression of NF- ĪŗB subunit. HB cells were treated with 0.8 Ī¼M CpG-ODN at indicated time period (0ā¼24 h) and the protein levels were determined using Western blot. Ī²-actin was used as an internal control. (<b>B</b>) Changes in NF- ĪŗB subunit protein levels compared with the control as determined by densitometric scanning of the immunoreactive bands. (<b>C</b>) Effects of CpG-ODN on the expression of AP-1 subunit. (<b>D</b>) Changes in AP-1 subunit protein levels compared with control as determined by densitometric scanning of the immunoreactive bands. (*P<0.05; **P<0.01, compare with the control) (<b>E</b>) Electrophoretic mobility shift analysis (EMSA) analysis of AP-1 in HB cell lines before and after treatment with 0.8 Ī¼M CpG-ODN at indicated time period (0ā¼24 h). (*P<0.05; **P<0.01, compared with the panel 1), (<sup>ā
ā
</sup>P<0.01, compared with the panel 5). (<b>F</b>) CpG-ODN treatment enhances the DNA-binding activity of AP-1(c-Fos/Jun-D) to the promoter of MMP-2 in a time-dependent manner.</p
Role of MMP-2 in TLR-9/AP-1 mediated cancer cell invasion.
<p>(<b>A</b>) Expression of TLR-9 protein in HB cells before and after 48 hr of transfection. Ī²-actin was used as an internal control. (<b>B</b>) CpG-ODN treatment does not enhance AP-1 activity in HB cells transfected with special siRNA against TLR-9. (**P<0.01, NS: no significant) (<b>C</b>) The interferon effect of AP-1 inhibitor and/or TLR-9-RNAi on the CpG-ODN induced MMP-2 expression/activity as well as subsequent cancer cell invasion. (**P<0.01, compared with the panel 1), (<sup>ā
ā
</sup>P<0.01, compared with the panel 2)</p
Effects of CpG-ODN on MMP-2 and MMP-9 expressions.
<p>(<b>A</b>) Analysis of MMP-2 and -9 protein expression in cells treated with indicated doses of CpG-ODN and harvested at 24 h. Ī²-actin served as an internal control. (<b>B</b>) Determined secretion of MMP-2 and -9 was subsequently quantified by ELISA analysis, and presented as means Ā± S.D. of three repeats from one independent study. (<b>C</b>) HB cells in serum-free medium were treated with various concentrations (0ā¼0.8 Ī¼M) of CpG-ODN for 24 h. The culture medium of cells after treatment was subjected to gelatin zymography to analyze the activity of MMP-2 and -9; *p<0.05; **p<0.01, compared with the control.</p
Forest plots of association between cyclin D1 overexpression with poor clinicopathological outcome in OSCC.
<p>(A). Tumor size, random-effects model; (B). Nodal metastasis, Peto one-step model; C. Histological grade, random-effects model; D. Clinical stage, fixed-effects model.</p