126 research outputs found

    Class-Imbalanced Semi-Supervised Learning for Large-Scale Point Cloud Semantic Segmentation via Decoupling Optimization

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    Semi-supervised learning (SSL), thanks to the significant reduction of data annotation costs, has been an active research topic for large-scale 3D scene understanding. However, the existing SSL-based methods suffer from severe training bias, mainly due to class imbalance and long-tail distributions of the point cloud data. As a result, they lead to a biased prediction for the tail class segmentation. In this paper, we introduce a new decoupling optimization framework, which disentangles feature representation learning and classifier in an alternative optimization manner to shift the bias decision boundary effectively. In particular, we first employ two-round pseudo-label generation to select unlabeled points across head-to-tail classes. We further introduce multi-class imbalanced focus loss to adaptively pay more attention to feature learning across head-to-tail classes. We fix the backbone parameters after feature learning and retrain the classifier using ground-truth points to update its parameters. Extensive experiments demonstrate the effectiveness of our method outperforming previous state-of-the-art methods on both indoor and outdoor 3D point cloud datasets (i.e., S3DIS, ScanNet-V2, Semantic3D, and SemanticKITTI) using 1% and 1pt evaluation

    A New Approach to Extract Fetal Electrocardiogram Using Affine Combination of Adaptive Filters

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    The detection of abnormal fetal heartbeats during pregnancy is important for monitoring the health conditions of the fetus. While adult ECG has made several advances in modern medicine, noninvasive fetal electrocardiography (FECG) remains a great challenge. In this paper, we introduce a new method based on affine combinations of adaptive filters to extract FECG signals. The affine combination of multiple filters is able to precisely fit the reference signal, and thus obtain more accurate FECGs. We proposed a method to combine the Least Mean Square (LMS) and Recursive Least Squares (RLS) filters. Our approach found that the Combined Recursive Least Squares (CRLS) filter achieves the best performance among all proposed combinations. In addition, we found that CRLS is more advantageous in extracting FECG from abdominal electrocardiograms (AECG) with a small signal-to-noise ratio (SNR). Compared with the state-of-the-art MSF-ANC method, CRLS shows improved performance. The sensitivity, accuracy and F1 score are improved by 3.58%, 2.39% and 1.36%, respectively.Comment: 5 pages, 4 figures, 3 table

    Spatio-Temporal AU Relational Graph Representation Learning For Facial Action Units Detection

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    This paper presents our Facial Action Units (AUs) recognition submission to the fifth Affective Behavior Analysis in-the-wild Competition (ABAW). Our approach consists of three main modules: (i) a pre-trained facial representation encoder which produce a strong facial representation from each input face image in the input sequence; (ii) an AU-specific feature generator that specifically learns a set of AU features from each facial representation; and (iii) a spatio-temporal graph learning module that constructs a spatio-temporal graph representation. This graph representation describes AUs contained in all frames and predicts the occurrence of each AU based on both the modeled spatial information within the corresponding face and the learned temporal dynamics among frames. The experimental results show that our approach outperformed the baseline and the spatio-temporal graph representation learning allows our model to generate the best results among all ablated systems. Our model ranks at the 4th place in the AU recognition track at the 5th ABAW Competition

    ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentation

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    Most recent scribble-supervised segmentation methods commonly adopt a CNN framework with an encoder-decoder architecture. Despite its multiple benefits, this framework generally can only capture small-range feature dependency for the convolutional layer with the local receptive field, which makes it difficult to learn global shape information from the limited information provided by scribble annotations. To address this issue, this paper proposes a new CNN-Transformer hybrid solution for scribble-supervised medical image segmentation called ScribFormer. The proposed ScribFormer model has a triple-branch structure, i.e., the hybrid of a CNN branch, a Transformer branch, and an attention-guided class activation map (ACAM) branch. Specifically, the CNN branch collaborates with the Transformer branch to fuse the local features learned from CNN with the global representations obtained from Transformer, which can effectively overcome limitations of existing scribble-supervised segmentation methods. Furthermore, the ACAM branch assists in unifying the shallow convolution features and the deep convolution features to improve model's performance further. Extensive experiments on two public datasets and one private dataset show that our ScribFormer has superior performance over the state-of-the-art scribble-supervised segmentation methods, and achieves even better results than the fully-supervised segmentation methods. The code is released at https://github.com/HUANGLIZI/ScribFormer.Comment: Accepted by IEEE Transactions on Medical Imaging (TMI

    ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentation

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    Most recent scribble-supervised segmentation methods commonly adopt a CNN framework with an encoder-decoder architecture. Despite its multiple benefits, this framework generally can only capture small-range feature dependency for the convolutional layer with the local receptive field, which makes it difficult to learn global shape information from the limited information provided by scribble annotations. To address this issue, this paper proposes a new CNN-Transformer hybrid solution for scribble-supervised medical image segmentation called ScribFormer. The proposed ScribFormer model has a triple-branch structure, i.e., the hybrid of a CNN branch, a Transformer branch, and an attention-guided class activation map (ACAM) branch. Specifically, the CNN branch collaborates with the Transformer branch to fuse the local features learned from CNN with the global representations obtained from Transformer, which can effectively overcome limitations of existing scribble-supervised segmentation methods. Furthermore, the ACAM branch assists in unifying the shallow convolution features and the deep convolution features to improve model’s performance further. Extensive experiments on two public datasets and one private dataset show that our ScribFormer has superior performance over the state-of-the-art scribble-supervised segmentation methods, and achieves even better results than the fully-supervised segmentation methods. The code is released at https://github.com/HUANGLIZI/ScribFormer

    Unipolar resistive switching of ZnO-single-wire memristors

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    Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B

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    Signal peptide (SP) is essential for protein secretion, and pathogenic variants in the SP of factor IX (FIX) have been identified in hemophilia B (HB). However, the underlying mechanism for the genotype-phenotype correlation of these variants has not been well studied. Here, we systematically examined the effects of 13 pathogenic point variants in the SP of FIX using different approaches. Our results showed that these point variants lead to HB by missense variants and/or aberrant premessenger RNA (pre-mRNA) splicing. The missense variants in a hydrophobic core (h-region) mainly affected the cotranslational translocation function of the SP, and those in C-terminal containing cleavage site (c-region) caused FIX deficiency mainly by disturbing the cotranslational translocation and/or cleavage of the SP. Almost absolute aberrant pre-mRNA splicing was only observed in variants of c.82T\u3eG, but a slight change of splicing patterns was found in variants of c.53G\u3eT, c.77C\u3eA, c.82T\u3eC, and c.83G\u3eA, indicating that these variants might have different degrees of impact on pre-mRNA splicing. Although two 6-nt deletion aberrant pre-mRNA splicing products caused FIX deficiency by disturbing the SP cleavage, they could produce some functional mature FIX, and vitamin K could increase the secretion of functional FIX. Taken together, our data indicated that pathogenic variants in the SP of FIX caused HB through diverse molecular mechanisms or even a mixture of several mechanisms, and vitamin K availability could be partially attributed to varying bleeding tendencies in patients carrying the same variant in the SP
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