Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature

Basaloid squamous cell carcinoma (BSCC) is a rare, but distinct histologic variant of squamous cell carcinoma in the head and neck region. It is considered to have a poor prognosis due to its aggressive behavior and tendency to metastasize. The usual sites of BSCC are the floor of the mouth, hypopharynx and base of the tongue, and according to the English-language literature its presentation in the gingiva is somewhat uncommon. In the current report, the unusual case of a 40-year-old male is presented; the patient exhibited a painless irregular mass in the maxillary gingiva, which infiltrated the maxillary sinus, as observed by computed tomography. Hematoxylin and eosin-stained sections revealed a diagnosis of BSCC with typical central necrosis in the cancer nests, which contained basaloid and squamous cells. Immunohistochemistry revealed that p63 was weakly positive, high molecular weight cytokeratin (CK) was focally positive, and S-100, CK7, CK14 and vimentin were negative. It must be noted that histopathology results may be incorrectly interpreted as adenoid cystic carcinoma, undifferentiated carcinoma and basal cell adenocarcinoma

ATM Transaction Status Feature Analysis and Anomaly Detection

In this paper, based on ATM transaction status analysis and anomaly detection problem, by analyzing the transaction statistics of a bank ATM application system, the characteristic parameters of ATM transaction status are extracted and analyzed, then a set of targets are designed. An abnormal monitoring scheme that can promptly and accurately alarm the four abnormal situations in which the trading volume is steep, the transaction failure rate is increased, the transaction processing is slow, and the transaction response time is too long. Firstly, the transaction data is divided to distinguish between working days, non-working days, trading volume troughs, and normal trading periods, to avoid data interference between different time periods and to take into account the data discontinuity. The characteristics of the anomaly data were identified by K-Means Clustering Analysis. Then the data is analyzed by B-P Neural Network method, the change rule of ATM transaction status with time is obtained. According to this rule, the ATM transaction status is judged, and the abnormal situation is alarmed in time. Finally, this paper increases the amount and type of data collected, then increases the influencing factors such as ATM popularity, holidays, transaction types into the model, uses the existing transaction data before and after the Spring Festival to verify, in order to obtain a more realistic monitoring and early warning program. The transaction status anomaly monitoring scheme designed in this paper not only can correctly judge but also timely alarm the financial aid equipment failure scenarios, so that the security of the financial self-service equipment trading system is guaranteed

第828回千葉医学会例会・第6回磯野外科例会 88-3.

Western blotting was performed to examine the protein levels of Twist in the indicated cells; β-actin was used as control. (JPG 151 kb

The Influence of Pulp and Paper Industry on Environment

Currently, paper consumption is globally increasing and at an unsustainable level. However, traditional paper production could release excessive greenhouse gas emissions or wastewater, resulting in environmental contamination. To make the result more visual and persuasive, this study takes Time magazine as an example to analyze the impacts of the papermaking process on the environment. This study analyzes energy consumption from several sectors in the paper industry, carbon dioxide emissions, and discharge of condensed wastewater to show current consumption during traditional pulp and paper production. Results show that the papermaking process would consume a lot of electricity during the pulp preparing, pulp condition, pulp preparation, manufacture paper with pulp, and pulp processing stages. Meanwhile, various degree of carbon emissions is generated based on the physical and chemical changes in materials during the papermaking process. Two kinds of wastewater, including black and white liquor, are produced in the papermaking process. Several countermeasures are suggested to achieve a low consumption and sustainable development of the pulp and paper industry to solve these environmental problems. The suggestion includes the surrogate of electronic paper, carbon capture and storage, and wastewater recycling

The distribution of Van Genuchten model parameters on soil-water characteristic curves in Chinese Loess Plateau and new predicting method on unsaturated permeability coefficient of loess.

The unsaturated permeability coefficients are often used to solve geotechnical problems associated with unsaturated soils. But it is very difficult to measure. However, the unsaturated permeability coefficients can be predicted by the Soil-water Characteristic Curves (SWCCs). The Van Genuchten Model (VG model) is very rife as it's smooth and good fitting, thus, it has the most research data. Therefore, the research data on VG model parameters (α, n, θs and θr) of Malan loess in Chinese Loess Plateau are collected in the past two decades to obtain the spatial distribution characteristics of parameters. The trend surface analysis method is employed to clarify the regional scale distribution and the variation regular pattern on ArcGIS. Then the linear regression method is utilized to fit the relationship between suction and water content in three different regions of Chinese Loess Plateau, which is divided according to the properties and particle gradation. By using this relationship and the trend surface analysis contour map, the unsaturated permeability coefficient of the sample can be predicted after measuring the saturated permeability coefficient. The example verification shows that the difference between the prediction results and the experimental results is very small when the sample has the lower saturation, and the deviation is slightly larger if it has the higher saturation, but they are all within the acceptable range. This method not only saves the test cost, but also considers the physical properties of the loess in the three different regions of the Loess Plateau. With the improvement of data and the gradual improvement of sampling density, the prediction accuracy will gradually improve. It can provide convenience for solving the engineering problems of loess and water and other engineering applications

Clinical and genetic analysis of two patients with primary ciliary dyskinesia caused by a novel variant of DNAAF2

Abstract Background The study describes the clinical manifestations and variant screening of two Chinese siblings with primary ciliary dyskinesia (PCD). They carry the same DNAAF2 genotype, which is an extremely rare PCD genotype in the Chinese population. In addition, the study illustrated an overview of published variants on DNAAF2 to date. Methods A two-child family was recruited for the study. Clinical manifestations, laboratory tests, bronchoscopic and otoscopic images, and radiographic data were collected. Whole blood was collected from siblings and their parents for whole-exome sequencing (WES) and Sanger sequencing to screen variants. Results The two siblings exhibited typical clinical manifestations of PCD. Two compound heterozygous variants in DNAAF2 were detected in both by WES. Nonsense variant c.156 C>A and frameshift variant c.177_178insA, which was a novel variant. Conclusion The study identified a novel variant of DNAAF2 in Chinese children with a typical phenotype of PCD, which may enrich our knowledge of the clinical, diagnostic and genetic information of DNAAF2-induced PCD in children

Dyed microspheres for quantification of UV dose distributions: Photochemical reactor characterization by lagrangian actinometry

Lagrangian actinometry represents a new method of photochemical reactor characterization. The method is based on an application of dyed microspheres, which were developed by attachment of (E) role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3e(E)(E)-5-[2-(methoxycarbonyl)ethenyl]cytidine (hereafter referred to as S role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3eSS) to polystyrene microspheres. S role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3eSS is a nonfluorescent molecule that when subjected to ultraviolet (UV) irradiation yields a single product, 3-β role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3eββ-D-ribofuranosyl-2,7-dioxopyrido[2,3-d role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3edd]pyrimidine (hereafter referred to as P role= presentation style= box-sizing: border-box; display: inline; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative; \u3ePP), which displays a strong fluorescence signal. Dyed microspheres were subjected to UV irradiation under a collimated beam and using a single-lamp, monochromatic (low pressure Hg), continuous-flow reactor. In parallel with these experiments, a biodosimetry experiment was conducted using Bacillus subtilis spores as the challenge organism. Particle-specific fluorescence intensity measurements were conducted on samples from the collimated-beam experiments and the flow-through reactor experiments by flow cytometry. Estimates of the dose distribution delivered by the flow-through reactor for each operating condition were developed by deconvolution of data resulting from flow cytometry analysis of these samples. In conjunction with these experiments, a numerical model was developed to simulate the behavior of the reactor system. A commercially available computational fluid dynamics package was used to simulate the flow field, while line-source integration was used to simulate the irradiance field. A particle-tracking algorithm was employed to interrogate the flow and irradiance field simulations for purposes of developing particle-specific (Lagrangian) estimates of dose delivery. Dose distribution estimates from the microspheres assays and the numerical simulations were combined with the measured dose–response behavior of B. subtilis spores to yield estimates of spore inactivation in the flow-through experiments. For the range of operating conditions used in these experiments, predictions of spore inactivation based on dose distribution estimates from both methods were in good agreement with each other, and with the measured spore inactivation behavior. Lagrangian actinometry is capable of yielding accurate, detailed measurements of dose delivery by continuous-flow UV systems. This method represents a substantial improvement over existing experiment-based methods of UV reactor characterization (e.g., biodosimetry) in that it yields a measurement of the dose distribution for a given operating condition. This method also represents an improvement over existing methods for validation of numerical simulations. Specifically, because this method yields a measurement of the dose distribution, it is possible to compare these measurements with predicted dose distributions from the numerical simulation. The combined application of biodosimetry, numerical modeling, and Lagrangian actinometry represents an extremely robust approach to reactor characterization and validation

The zoning of the Chinese Loess Plateau(Only the boundary of the Loess Plateau comes from Huang [32], illustrative purposes only).

The zoning of the Chinese Loess Plateau(Only the boundary of the Loess Plateau comes from Huang [32], illustrative purposes only).</p