Souvenir Postcard Folder: Souvenir Folder of Beautiful Jacksonville, Florida

Souvenir Postcard Folder: Souvenir Folder of Beautiful Jacksonville, Florida; 1915 (134)https://digitalcommons.unf.edu/mette_postcardimages/1224/thumbnail.jp

The performance of PREPARE on realistic simulation is comparable to polygamous Wright-Fisher simulations.

<p>The simulated population grew from 160 individuals of the and HapMap populations to 846 individuals in 200 years. This simulation accounts for IBD detection errors, asynchronous mating and dynamic population size.</p

Distribution of relationship scores under specific true relationships.

<p>Distribution of relationship scores under specific true relationships.</p

Depicting cases where edge removal rules are required in polygamous pedigree reconstruction.

<p>Redundant graph edges are dashed red, correct edges in solid black.</p

Four examples of vertex contractions, typical for first, second, and third generations.

<p>Founders are filled with Grey. Extant individuals are outlined in blue. Green arrows stand for the contraction action.</p

Simulated IBD feature distribution in monogamous and polygamous populations.

<p>The overlap in polygamous distributions is the main challenge in reconstructing pedigrees of real populations.</p

PREPARE successfully isolates the 4 generation pedigree found by CARROT.

<p>Nodes correspond to individuals, and edges to parent offspring relationships. The last generation individuals are real HapMap individuals, and the other nodes are ancestors predicted by PREPARE.</p

Examples for possible ancestry structures created for individuals and in order to test the relationship between them.

<p>The triangles under and represent their existing descendants, edges represent parent-offspring relationship.</p

An example for the construction of in the first generation.

<p>An example for the construction of in the first generation.</p

Attempting to reconstruct the simple pedigree on the left, from the genotypes of extant generation (bright blue).

<p>Considering observed genetic similarity of extant descendants only, we cannot distinguish which of the four parents in the second generation are siblings (Correctly inferred sibling relationship are colored blue, and wrong potential sibling-relationships in dashed red).</p