72 research outputs found

    Economic Analysis of Knowledge: The History of Thought and the Central Themes

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    Following the development of knowledge economies, there has been a rapid expansion of economic analysis of knowledge, both in the context of technological knowledge in particular and the decision theory in general. This paper surveys this literature by identifying the main themes and contributions and outlines the future prospects of the discipline. The wide scope of knowledge related questions in terms of applicability and alternative approaches has led to the fragmentation of research. Nevertheless, one can identify a continuing tradition which analyses various aspects of the generation, dissemination and use of knowledge in the economy

    Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

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    Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

    The sero-conversion of the people of the Nelson Mandela metropole, 1985 - 2021.

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    The authors draw attention to the little researched pandemic of HIV/AIDS in the Western area of the Eastern Cape, South Africa. They use population projection programs and new historical case level data which has a broader base than the national ante natal clinic (anc) data. They demonstrate the utility of the component method for projecting urban population trends as opposed to commonly used mathematical (exponential or logistic) projections. While there is much more work involved in an urban component projection because of problems of recovering reliable in-migration data, the final product of the component projection are of such value to planners that it is suggested that all South African city planners could benefit from such projections. This study also attempts to establish that if the HIV pandemic is allowed to run unchecked, the total population of the Nelson Mandela Metropole will be just under two million people by the year 2021. Without Aids it would be between 2.5 and 4 million. The authors analyze the new data with a view to understand the probable historical vectors of the pandemic and to enable policy formulation, interventions and planning. Any attempt to forecast the course of an urban HIV pandemic is fraught with difficulties and uncertainties. These relate primarily to the number of assumptions which must be made in building forecasting models, often with historical data that is not reliable. The results of any model should therefore be treated with caution and must be used responsibly. That uncertainty, however, should not deter attempts at developing realistic forecasts for the future course of the HIV/AIDS pandemic at the urban level, since these local projections are essential in attracting and recruiting the attention of the stakeholder urban planners and managers who need to understand the possible impact of this disease on their communities, and to plan appropriately

    Historical relevance?: ten sketches of women illegally enslaved at the Cape, 1823 to 1830.

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    Die artikel handel oor die verhale van slawevroue wat deel was van die slawehandelsproses teen die einde van die 18e eeu. Hulle is na die Kaap de Goede Hoop gebring as vry slawe of - soos hul eienaars gemeen het - as “geskenke”. Hierdie mini biografieë vertel die verhale van vroue wie se lot was dié van vervreemding van hul geboorteland, en slawerny in ‘n nuwe vreemde land. Slawevroue het protesteer en hul situasie by die owerhede aangemeld om sodoende hul vryheid terug te win toe dit moontlik was in die 1820s. Persoonlike getuienisse is beskikbaar van sulke vroue soos opgeteken in die Boek van Klagtes deur die Guardian of Slaves gedurende die opskudding van die 1820s. In die artikel word hierdie getuienisse kortliks bespreek, waarop elk se historiese relevansie vervolgens bepaal word
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