6 research outputs found
Consideration of Solid-Phase Synthesis with Reference to Quinolone Antibiotics
The general utility of solid-phase synthesis for creating libraries of compounds will be discussed with particular reference paid to the development of a solid-phase organic synthetic route to quinolones. Using the DIVERSOMERĀ® technology a library of quinolones have been
prepared, purified and analyzed. Additionally, the issue of resin impurities and by-products will be discussed