6,277 research outputs found

    Race as a Dimension in Children\u27s TV Advertising: The Need for More Research

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    Most of the current research in the area of television advertising to children deal entirely with white populations. This exclusion of black subjects exists in spite of an abundance of research in education, sociology and psychology which suggests differences in the socialization of black and white children. The present article reviews major studies of television and children and black versus white child development. The authors conclude with several suggestions for further research

    Intermittent Bolus versus Continuous Infusion of Propofol for Deep Sedation during ABR/Nuclear Medicine Studies

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    Objective  A comparison of intermittent bolus (IB) versus continuous infusion of propofol for deep sedation. Material and Methods  A retrospective review of patients sedated for Auditory Brainstem Response (ABR)/nuclear medicine studies between September 2008 and February 2015. A ketamine bolus (0.5 mg/kg 20 kg) followed by propofol bolus of 1 mg/kg over 2 minutes. In the IB group, maintenance of deep sedation was with incremental bolus of 10 to 20 mg of propofol. In continuous infusion group (CG), maintenance was with a continuous infusion of 83 mcg/kg/min of propofol. Results  Of the 326 cases completed, 181 were in CG group and 145 were in IB group. There were no statistical differences in patient's age, weight, and American Society of Anesthesiologist (ASA) classification. The cardiovascular and respiratory parameters in the two groups were not different statistically. Mean total propofol dose was higher in CG group versus IB group (CG 7.6 mg ± 3.6 mg, IB 6.5 mg ± 3.6 mg; p  = 0.008). Procedure time in CG group was longer by 8 minutes compared with IB group (CG 49.8 min ± 25.4 min versus 42.3 min ± 19.2 min; p  = .003). CG group has both shorter recovery time (CG 8.1 min ± 4.7 min versus IB 10.0 min ± 8.5 min; p  = 0.01) and discharge time. Conclusion  Satisfactory sedation and completion of the procedure was accomplished with both sedation protocols

    Yang-Baxter Deformations Beyond Coset Spaces (a slick way to do TsT)

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    Yang-Baxter string sigma-models provide a systematic way to deform coset geometries, such as AdSp×SpAdS_p \times S^p, while retaining the σ\sigma-model integrability. It has been shown that the Yang-Baxter deformation in target space is simply an open-closed string map that can be defined for any geometry, not just coset spaces. Given a geometry with an isometry group and a bivector that is assumed to be a linear combination of antisymmetric products of Killing vectors, we show the equations of motion of (generalized) supergravity reduce to the Classical Yang-Baxter Equation associated with the isometry group, proving the statement made in [1]. These results bring us closer to the proof of the "YB solution generating technique" for (generalized) supergravity advertised in [1] and in particular provide an economical way to perform TsT transformations.Comment: 33 pages; v2 typos fixed and reference added; v3 further improvements in text, matches published version; v4 typo in expression for B (4.9) correcte

    Nearing Extremal Intersecting Giants and New Decoupled Sectors in N = 4 SYM

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    We study near-horizon limits of near-extremal charged black hole solutions to five-dimensional U(1)3U(1)^3 gauged supergravity carrying two charges, extending the recent work of Balasubramanian et.al. We show that there are two near-horizon decoupling limits for the near-extremal black holes, one corresponding to the near-BPS case and the other for the far from BPS case. Both of these limits are only defined on the 10d IIB uplift of the 5d black holes, resulting in a decoupled geometry with a six-dimensional part (conformal to) a rotating BTZ X S3S^3. We study various aspects of these decoupling limits both from the gravity side and the dual field theory side. For the latter we argue that there should be two different, but equivalent, dual gauge theory descriptions, one in terms of the 2d CFT's dual to the rotating BTZ and the other as certain large R-charge sectors of d=4,N =4 U(N) SYM theory. We discuss new BMN-type sectors of the N=4 SYM in the N→∞N\to\infty limit in which the engineering dimensions scale as N3/2N^{3/2} (for the near-BPS case) and as N2N^2 (for the far from BPS case).Comment: 44 pages, references added, minor change

    Impact of pregnancy on cancer survival: Experience at a tertiary care hospital

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    Objectives: To assess the overall survival of pregnant women diagnosed with cancer during pregnancy or became pregnant thereafter.Methods: A retrospective medical record review of 90 patients who were diagnosed with cancer when pregnant or who became pregnant thereafter between 1996 and 2015 in Aga Khan University Hospital, Karachi.Results: A total of 90 patients were analyzed. The malignancies that expectant mothers had were, breast cancer 38 (42.2%), hematological cancers 29 (32.2%), brain cancer 10 (11.1%), and other malignancies 13 (14.4%) that included thyroid cancers, gestational trophoblastic disease and synovial tumor of foot. We observed only four deaths out of 90 patients and mean survival time in pregnant patients with malignancies was 17.98 years [CI 16.35-19.31].Conclusions: The diagnosis of most cancer types before or during pregnancy does not influence on overall survival of patients

    II in generalized supergravity

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    We showed in previous work that for homogeneous Yang-Baxter (YB) deformations of AdS5×_5\timesS5^5, the open string metric and coupling, and as a result the closed string density e−2Φge^{-2 \Phi} \sqrt{g}, remain undeformed. In this work, in addition to extending these results to the deformation associated with the modified CYBE, or η\eta-deformation, we identify the Page forms as the open string counterpart for RR fields and demonstrate case by case that the non-zero Page forms remain invariant under YB deformations. We give a physical meaning to the Killing vector II of generalized supergravity and show for all YB deformations: 1) II appears as a current for center of mass motion on the worldvolume of a D-branes probing the background, 2) II is equal to the divergence of the noncommutativity parameter, 3) II exhibits "holographic" behavior, where the radial component of II vanishes at the AdS boundary, and 4) in pure spinor formalism II is related to a certain state in the BRST cohomology.Comment: 11 pages, 2 column; v2 references updated; v3 to appear in EPJ

    On the Solution of the Number-Projected Hartree-Fock-Bogoliubov Equations

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    The numerical solution of the recently formulated number-projected Hartree-Fock-Bogoliubov equations is studied in an exactly soluble cranked-deformed shell model Hamiltonian. It is found that the solution of these number-projected equations involve similar numerical effort as that of bare HFB. We consider that this is a significant progress in the mean-field studies of the quantum many-body systems. The results of the projected calculations are shown to be in almost complete agreement with the exact solutions of the model Hamiltonian. The phase transition obtained in the HFB theory as a function of the rotational frequency is shown to be smeared out with the projection.Comment: RevTeX, 11 pages, 3 figures. To be published in a special edition of Physics of Atomic Nuclei (former Sov. J. Nucl. Phys.) dedicated to the 90th birthday of A.B. Migda

    H1-antihistamines for primary mast cell activation syndromes: a systematic review

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    Background Primary mast cell activation syndromes (MCAS) are a group of disorders presenting with symptoms of mast cell mediator release. Objectives To assess the effectiveness and safety of orally administered H1-antihistamines in the treatment of primary MCAS compared with placebo and other pharmacologic treatments. Methods We systematically searched five databases and three trial repositories and contacted an international panel of experts to identify published and unpublished trials. Results A total of 36 potentially relevant studies were identified. Of these, five crossover trials, enrolling a total of 71 patients (63 adults), met the eligibility criteria. All five of these studies were judged to be at moderate or high risk of bias. Two studies compared an H1-antihistamine with placebo, two compared two different H1-antihistamines, and one study compared H1- and H2-antihistamines with oral cromolyn sodium. Four of the five randomized controlled trials were historic (reported from 1983–1993), small (enrolling 8–15 patients), and used agents and/or dosing regimens that are now less commonly used in clinical practice (i.e. azelastine, chlorpheniramine, hydroxyzine, and ketotifen). The fifth trial, which enrolled 33 adults with cutaneous and systemic mastocytosis found 4 weeks of treatment with the second-generation H1-antihistamine rupatadine, compared with placebo, resulted in significant improvements in quality of life, symptom control (itching, wheals and flares, flushing, tachycardia, and headache, but not gastrointestinal symptoms), and reduction in itching and whealing after standardized skin provocation to elicit Darier's sign. Conclusions There is an urgent need for large, well-designed, double-blind, placebo-controlled randomized trials investigating the effectiveness, cost-effectiveness, and safety of second-generation H1-antihistamines in treatment of primary MCAS
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