Comment on "Spectroscopic Evidence for Multiple Order Parameters in the Heavy Fermion Superconductor CeCoIn5"

This is a comment on recent paper by Rourke et al. titled "Spectroscopic Evidence for Multiple Order Parameters in the Heavy Fermion Superconductor CeCoIn5" (cond-mat/0409562v1 22 Sep 2004). We argue that the features observed by Rourke etal. arise from their contact not being in the ballistic limit.Comment: 4 pages with figures (pdf

Simulating Patho-realistic Ultrasound Images using Deep Generative Networks with Adversarial Learning

Ultrasound imaging makes use of backscattering of waves during their interaction with scatterers present in biological tissues. Simulation of synthetic ultrasound images is a challenging problem on account of inability to accurately model various factors of which some include intra-/inter scanline interference, transducer to surface coupling, artifacts on transducer elements, inhomogeneous shadowing and nonlinear attenuation. Current approaches typically solve wave space equations making them computationally expensive and slow to operate. We propose a generative adversarial network (GAN) inspired approach for fast simulation of patho-realistic ultrasound images. We apply the framework to intravascular ultrasound (IVUS) simulation. A stage 0 simulation performed using pseudo B-mode ultrasound image simulator yields speckle mapping of a digitally defined phantom. The stage I GAN subsequently refines them to preserve tissue specific speckle intensities. The stage II GAN further refines them to generate high resolution images with patho-realistic speckle profiles. We evaluate patho-realism of simulated images with a visual Turing test indicating an equivocal confusion in discriminating simulated from real. We also quantify the shift in tissue specific intensity distributions of the real and simulated images to prove their similarity.Comment: To appear in the Proceedings of the 2018 IEEE International Symposium on Biomedical Imaging (ISBI 2018

The role of critical current on point contact Andreev Reflection spectrum between a normal metal and a superconductor

The point contact spectrum between a normal metal and a superconductor often shows unexpected sharp dips in the conductance at voltage values larger than the superconducting energy gap. These dips are not predicted in the Blonder-Tinkham-Klapwizk (BTK) theory, commonly used to analyse these contacts. We present here a systematic study of these dips in a variety of contacts between different combinations of a superconductor and a normal metal. From the correlation between the characteristics of these dips with the contact area, we can surmise that such dips are caused by the contact not being in the ballistic limit. An analysis of the possible errors introduced while analysing such a spectrum with the standard BTK model is also presented.Comment: 16 pages, PS, figure include

Role of DNA methyltransferase 3A and 3B, in Human Cancer

DNA Methylation acts as an essential regulatory mechanism of transcription affecting chromatin structure, which is established and maintained by the co-ordinate action of three DNA methyltransferases: DNMT1, DNMT3A and DNMT3B and histone modifications. Recent studies show that epigenetic change plays a major role in silencing a variety of methylated tissue-specific and imprints genes in many cancer types. Lymph node cancer is considered to result in part from the accumulation of multiple genetic alterations and leading to oncogene over expression and loss of function of tumor suppressor. The aim of this study was to check the expression of DNMT3A and DNMT3B in both normal and cancer cell. Both DNMT3A and DNMT3B shows over expression in cancer cell indicating their involvement in lymph node cancer