Civic leadership and the Edinburgh lawyers in Eighteenth century Scotland

The majority of the letters from Lord Milton quoted are copies which he kept of his more important communications. His main correspondent was the Earl of Ilay (1706), 3rd Duke of Argyll (1743). The Argyll papers at Inveraray Castle are unavailable. Ilay's papers apart from estate material are not at Inveraray, however, being included in his English estate and going to his mistress Mrs Anne Williams or Shireburn, then to her son by him, William Williams or Campbell, and then to the latter's son Archibald Campbell, who gave William Coxe access to them for his Memoirs of Sir Robert Walpole (1798). After that these papers were lost (Sir Lewis Namier having failed to trace them in recent times) and might, if found, be disappointing in one respect, the injunction of Milton to Ilay being to burn his (Milton's) letters. Fortunately Ilay's letters to Milton are preserved in the latter's vast archives (the bulk of the Saltoun Papers at the National Library of Scotland). It is evident that Milton systematically stored every scrap of paper addressed to him. Milton is correctly described as plain Andrew Fletcher before he took the judicial title of Milton from part of his uncle's and father's estate of Salton (there already being a Lord Salton, in the Scots peerage). And his proper title during the centre of his career was, according to the usage of the time, "the Lord Justice Clerk", the designation of Milton not then applying. For simplicity's sake, however, he is referred to throughout as Milton. Similarly Ilay is always referred to as Ilay rather than Argyll to avoid confusing him with his brother the 2nd Duke of Argyll. And the 18th century spelling of Salton is preferred to the preciously antique form of Saltoun now prevailing. I am greatly indebted to Professor R. H. Campbell for his valuable advice and unstinting encouragement, and to Mrs Margaret Anderson, Dr Anand Chitnis, Dr Derek Dow, Dr Alastair Durie, Mrs Rita Hemphill, Mr Murdo MacDonald, Mr Michael Moss, Dr Alexander Murdoch, Miss Chris Robertson, Mr John Simpson, Miss Veronica Stokes, Mr Arnott Wilson, the Secretaries of the Royal Bank of Scotland and the Bank of Scotland and the staff of the National Library of Scotland and the Scottish Record Office for their generous help and cooperation

Infection control and the significance of sputum and other respiratory secretions from adult patients with cystic fibrosis

BACKGROUND: There is limited data available on the environmental and public health impact of the microbiological hazards associated with sputa from patients with cystic fibrosis [CF]. Pseudomonas aeruginosa, Burkholderia cenocepacia (formerly Burkholderia cepacia genomovar III), Staphylococcus aureus and Stenotrophomonas maltophilia are bacterial pathogens which are commonly found in the sputum of CF patients. A study was performed to ascertain the amount of sputum produced relating to microbial loading, as well as the diversity of bacteria present in a population of adult patients, with particular attention to pathogenic organisms. METHODS: Sputum from adult [>18 years old] CF patients [n = 20], chosen randomly from a population of 138 CF patients, was collected over a 24 h period on admission to the in-patient CF unit and enumerated quantitatively, as well as the sputa from 138 adult CF patients was examined qualitatively for the presence of infecting microflora. In addition, all different phenotypes from the sputum of each patient were identified phenotypically employing a combination of conventional identification methods [e.g. oxidase], as well as the API Identification schemes [API 20 NE, API 20 E]. RESULTS: This study demonstrated that patients with cystic fibrosis generate large numbers of bacteria in their sputum, approximating to 10(9 )organisms per patient per day. Although these organisms are introduced to the environment from the respiratory tract mainly via sputum, relatively few represent true bacterial pathogens and therefore are not clinically important to the general public who are immunocompotent. The greatest risk of such environmental microbial loading is to other patients with CF and therefore CF patients should be made aware of the hazards of acquiring such organisms from the environment, as well as socializing with other CF patients with certain transmissible types, such as Pseudomonas aeruginosa and Burkholderia cenocepacia. CONCLUSIONS: Environmental health professionals should therefore be aware that CF patients are a greater risk to their peer grouping rather than to the general public or health care workers and that good personal hygiene practices with CF patients should be encouraged to minimize environmental contamination and potential acquistion

S-Band Transponder Multi-Network Compatibility, Space Environment and Radiation Testing

This paper presents the development and testing of the Software Define Radio (SDR) transceiver to meet the emerging needs for SmallSat communication and navigation. Vulcan Wireless and NASA Goddard Space Flight Center (GSFC) collaborated in testing the Vulcan Wireless S-band SDR engineering model. Apart from testing, communication link analysis was performed for a Low Earth Orbit (LEO) 400 km scenario. The results of the compatibility, radiation, environmental testing, and link analysis are presented. Also, this paper reviews a set of SmallSat missions under development at NASA GSFC