Age-group specific WBC in patients with dengue, OFI and influenza in the first 72 hours of illness.

<p>Box and whiskers (maximum and minimum) indicate the mean and spread of WBC in the different groups of patients. Dotted line indicates threshold for leukopenia (WBC<4,500 cells/µL). ***indicates p<0.0001 as determined using the Mann Whitney U test.</p

Age-specific features of probable dengue diagnosis using the WHO 1997 or 2009 classification schemes.

<p>PPV and NPV denote positive and negative predictive values, respectively.</p><p>Values in parentheses are the 95% confidence intervals.</p

Age-specific features of using fever and leukopenia for probable dengue diagnosis.

<p>Leukopenia is defined as WBC<4,500 cells/µxL.</p><p>AUC indicates area under the curve.</p><p>PPV and NPV denote positive and negative predictive values, respectively.</p><p>Values in parentheses are the 95% confidence intervals.</p

Laboratory parameters in dengue patients who received hospitalized or ambulatory care only.

<p>Shown are median values with the 25^th and 75^th percentiles in parentheses.</p><p>Chi-square test with Yates' continuity correction was used except where indicated.</p><p>*Mann Whitney U test.</p><p>∧Cp indicates crossover point on the real-time RT-PCR, which is a semi-quantitative indicator of viremia levels. Lower Cp values indicate higher viremia levels and vice versa.</p>#<p>IgG seropositivity indicates secondary dengue infection.</p><p>WBC indicates white blood cell count.</p

Demographics of the hospitalized dengue cases with severe or non-severe dengue.

<p>Chi-square test with Yates' continuity correction was used except where indicated.</p><p>*Mann-Whitney U test.</p>#<p>One patient was admitted for a total of 37 days due to lack of a caregiver at home. Data from this patient was treated as an outlier and removed from analysis.</p

Demographics of the dengue, OFI and influenza patients enrolled into the study.

<p>All P values shown are analysed in comparison to dengue. Chi-square test with Yates' continuity correction was used to determine statistical significance for all parameters except mean age.</p><p>*Mann Whitney U test was used to determine P value.</p><p>∧Some patients in these categories have more than one pre-existing co-morbidities.</p

The WHO 1997 and 2009 classification schemes and the parameters used in this study.

<p>The WHO 1997 and 2009 classification schemes and the parameters used in this study.</p

The early clinical features and outcomes of dengue, OFI and influenza.

<p>∧Shown are median values with the 25^th and 75^th percentiles in parentheses.</p><p>Chi-square test with Yates' continuity correction was used except where indicated. *Mann Whitney U test.</p><p>*Mann Whitney U test.</p