1 research outputs found
Case Report - Acquired Pure Red Cell Aplasia in a Child
Primary acquired pure red cell aplasia is a rare occurrence in
childhood. An eleven-year old boy presented to us with pallor, which
required multiple packed red cell transfusions. He did not have
hepatosplenomegaly, jaundice or lymphadenopathy. Bone marrow
examination revealed the diagnosis of pure red cell aplasia. All
possible investigations were done to exclude secondary causes of pure
red cell aplasia. No secondary cause was found on investigations.
Rheumatoid factor and anti-nuclear antibodies were positive. He was
started on oral steroids, to which he did not respond. He was then
given cyclosporine A. Response to cyclosporine was dramatic and the
child now does not require any transfusions