36 research outputs found

    Spectroscopic Links Among Giant Planet Irregular Satellites and Trojans

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    We collect near-infrared spectra (∼0.75−2.55 μm\sim0.75-2.55\ \mu m) of four Jovian irregular satellites and visible spectra (∼0.32−1.00 μm\sim0.32-1.00\ \mu m) of two Jovian irregular satellites, two Uranian irregular satellites, and four Neptune Trojans. We find close similarities between observed Jovian irregular satellites and previously characterized Jovian Trojans. However, irregular satellites' unique collisional histories complicate comparisons to other groups. Laboratory study of CM and CI chondrites show that grain size and regolith packing conditions strongly affect spectra of dark, carbonaceous materials. We hypothesize that different activity histories of these objects, which may have originally contained volatile ices that subsequently sublimated, could cause differences in regolith grain-size or packing properties and therefore drive spectral variation. The Uranian satellites Sycorax and Caliban appear similar to TNOs. However, we detect a feature near 0.7 μm\mu m on Sycorax, suggesting the presence of hydrated materials. While the sample of Neptune Trojans have more neutral spectra than the Uranian satellites we observe, they remain consistent with the broad color distribution of the Kuiper belt. We detect a possible feature near 0.65-0.70 μm\mu m on Neptune Trojan 2006 RJ103, suggesting that hydrated material may also be present in this population. Characterizing hydrated materials in the outer solar system may provide critical context regarding the origins of hydrated CI and CM chondrite meteorites. We discuss how the hydration state(s) of the irregular satellites constrains the thermal histories of the interiors of their parent bodies, which may have formed among the primordial Kuiper belt.Comment: 4 Tables, 8 Figures. Accepted to PS

    Compositional Constraints for Lucy Mission Trojan Asteroids via Near-Infrared Spectroscopy

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    We report near-infrared (0.7-2.5 micron) reflectance spectra for each of the six target asteroids of the forthcoming NASA Discovery-class mission Lucy. Five Jupiter Trojans (the binary (617) Patroclus system, (3548) Eurybates, (21900) Orus, (11351) Leucus, and (15094) Polymele) are well-characterized, with measurable spectral differences. We also report a survey-quality spectrum for main belt asteroid (52246) Donaldjohanson. We measured a continuum of spectral slopes including "red" (Orus, Leucus), "less red" (Eurybates, Patroclus-Menoetius) and intermediate (Polymele), indicating a range of compositional end-members or geological histories. We perform radiative transfer modeling of several possible surface compositions. We find that the mild-sloped spectra and low albedo of Patroclus and Eurybates imply similar compositions. Eurybates (~7 wt.% water ice) and Patroclus (~4 wt.% water ice) are consistent with a hydrated surface. Models for Orus and Leucus are consistent with each other and require a significantly more reddening agent (e.g. iron-rich silicates or tholin-like organics). Polymele has a linear spectrum like Patroclus, but a higher albedo more closely aligned with Orus/Leucus, defying simple grouping. Solar system formation models generally predict that the Jovian Trojans accreted in the outer solar system. Our observations and analysis are generally consistent with this expectation, although not uniquely so.Comment: Accepted by AJ. 10 Figures, 5 Table

    90Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies

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    AbstractBackgroundFor patients with metastatic pancreatic adenocarcinoma, there are no approved or established treatments beyond the 2nd line. A Phase Ib study of fractionated radioimmunotherapy was undertaken in this setting, administering 90Y-clivatuzumab tetraxetan (yttrium-90-radiolabelled humanised antibody targeting pancreatic adenocarcinoma mucin) with or without low radiosensitising doses of gemcitabine.MethodsFifty-eight patients with three (2–7) median prior treatments were treated on Arm A (N=29, 90Y-clivatuzumab tetraxetan, weekly 6.5mCi/m2doses×3, plus gemcitabine, weekly 200mg/m2 doses×4 starting 1week earlier) or Arm B (N=29, 90Y-clivatuzumab tetraxetan alone, weekly 6.5mCi/m2doses×3), repeating cycles after 4-week delays. Safety was the primary endpoint; efficacy was also evaluated.ResultsCytopaenias (predominantly transient thrombocytopenia) were the only significant toxicities. Fifty-three patients (27 Arm A, 26 Arm B, 91% overall) completed ⩾1 full treatment cycles, with 23 (12 Arm A, 11 Arm B; 40%) receiving multiple cycles, including seven (6 Arm A, 1 Arm B; 12%) given 3–9 cycles. Two patients in Arm A had partial responses by RECIST criteria. Kaplan–Meier overall survival (OS) appeared improved in Arm A versus B (hazard ratio [HR] 0.55, 95% CI: 0.29–0.86; P=0.017, log-rank) and the median OS for Arm A versus Arm B increased to 7.9 versus 3.4months with multiple cycles (HR 0.32, P=0.004), including three patients in Arm A surviving >1year.ConclusionsClinical studies of 90Y-clivatuzumab tetraxetan combined with low-dose gemcitabine appear feasible in metastatic pancreatic cancer patients beyond 2nd line and a Phase III trial of this combination is now underway in this setting

    Middle-status conformity revisited: The interplay between achieved and ascribed status

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    Decisions about conforming to or deviating from conventional practices in a field is an important concern of organization and management theory. The position that actors occupy in the status hierarchy has been shown to be an important determinant of these decisions. The dominant hypothesis, known as middle-status-conformity, posits that middle-status actors are more likely to conform to conventional practices than high- and low-status actors do. We challenge this hypothesis by revisiting its fundamental assumptions and developing a theory where actors’ propensity to conform based on their achieved status further depends on their ascribed status that actors inherit from their social group. Specifically, we propose that middle-status conformity applies only to actors who have a sense of security, based on their high ascribed status. For actors with low ascribed status, we propose that high-and low-status actors show greater conformity than middle-status actors. We test our hypotheses using data from the U.S. symphony orchestras from 1918 to 1969

    Grain Size Effects on UV–MIR (0.2–14 μm) Spectra of Carbonaceous Chondrite Groups

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    Carbonaceous chondrites are among the most important meteorite types and have played a vital role in deciphering the origin and evolution of our solar system. They have been linked to low-albedo C-type asteroids, but due to subdued absorption bands, definitive asteroid–meteorite linkages remain elusive. A majority of these existing linkages rely on fine-grained (typically < 45 μ m) powders across a limited wavelength range in the visible to near-infrared (0.35–2.5 μ m). While this is useful in interpreting the fine-grained regolith of larger main-belt objects like Ceres, recent spacecraft missions to smaller near-Earth asteroids (NEAs), such as Bennu and Ryugu, have shown that their surfaces are dominated by larger grain size material. To better interpret the surfaces of these smaller, carbonaceous NEAs, we obtained laboratory reflectance spectra of seven carbonaceous chondrite meteorite groups (CI, CM, CO, CV, CR, CK, C2-ungrouped) over the ultraviolet to mid-infrared range (0.2–14 μ m). Each meteorite contained five grain size bins (45–1000 μ m) to help constrain spectral grain size effects. We find a correlation between grain size and absolute reflectance, spectral slope, band depth, and the Christiansen feature band center. Principal component analysis of grain size variation illustrates a similar trend to lunar-style space weathering. We also show that the Bus–DeMeo asteroid taxonomic classification of our samples is affected by grain size, specifically shifting CM2 Aguas Zarcas from a Ch-type to B-type with increasing grain size. This has implications for the parent body of the OSIRIS-REx target, Bennu. With Aguas Zarcas, we present results from Hapke modeling

    The Nature of Low-Albedo Small Bodies from 3-μ\mum Spectroscopy: One Group that Formed Within the Ammonia Snow Line and One that Formed Beyond It

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    We present evidence, via a large survey of 191 new spectra along with previously-published spectra, of a divide in the 3-μ\mum spectral properties of the low-albedo asteroid population. One group ("Sharp-types" or ST, with band centers << 3 μ\mum) has a spectral shape consistent with carbonaceous chondrite meteorites, while the other group ("not-Sharp-types" or NST, with bands centered >> 3 μ\mum) is not represented in the meteorite literature but is as abundant as the STs among large objects. Both groups are present in most low-albedo asteroid taxonomic classes, and except in limited cases taxonomic classifications based on 0.5-2.5-μ\mum data alone cannot predict whether an asteroid is ST or NST. Statistical tests show the STs and NSTs differ in average band depth, semi-major axis, and perihelion at confidence levels ≥\ge98\%, while not showing significant differences in albedo. We also show that many NSTs have a 3-μ\mum absorption band shape like Comet 67P, and likely represent an important small-body composition throughout the solar system. A simple explanation for the origin of these groups is formation on opposite sides of the ammonia snow line, with the NST group accreting H2O and NH3 and the ST group only accreting H2O, with subsequent thermal and chemical evolution resulting in the minerals seen today. Such an explanation is consistent with recent dynamical modeling of planetesimal formation and delivery, and suggests that much more outer solar system material was delivered to the main asteroid belt than would be thought based on the number of D-class asteroids found today.Comment: Accepted by Planetary Science Journal, 18 May 2022. 77 total pages, 14 total tables and 14 total figures, including 22 pages of supplementary text, 1 supplementary figure, and 3 supplementary table

    Dark Comets? Unexpectedly Large Nongravitational Accelerations on a Sample of Small Asteroids

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    We report statistically significant detections of nonradial, nongravitational accelerations based on astrometric data in the photometrically inactive objects 1998 KY _26 , 2005 VL _1 , 2016 NJ _33 , 2010 VL _65 , 2016 RH _120 , and 2010 RF _12 . The magnitudes of the nongravitational accelerations are greater than those typically induced by the Yarkovsky effect, and there is no radiation-based, nonradial effect that can be so large. Therefore, we hypothesize that the accelerations are driven by outgassing and calculate implied H _2 O production rates for each object. We attempt to reconcile outgassing-induced acceleration with the lack of visible comae or photometric activity via the absence of surface dust and low levels of gas production. Although these objects are small, and some are rapidly rotating, the surface cohesive forces are stronger than the rotational forces, and rapid rotation alone cannot explain the lack of surface debris. It is possible that surface dust was removed previously, perhaps via outgassing activity that increased the rotation rates to their present-day value. We calculate dust production rates of order ∼10 ^−4 g s ^−1 in each object, assuming that the nuclei are bare, within the upper limits of dust production from a sample stacked image of 1998 KY _26 of M˙Dust<0.2{\dot{M}}_{\mathrm{Dust}}\lt 0.2 g s ^−1 . This production corresponds to brightness variations of order ∼0.0025%, which are undetectable in extant photometric data. We assess the future observability of each of these targets and find that the orbit of 1998 KY _26 —which is also the target of the extended Hayabusa2 mission—exhibits favorable viewing geometry before 2025
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