Optimal Dispatch of Microgrid with Combined Heat and Power System Considering Environmental Cost

With the rapid development of wind power generation and photovoltaic power generation, the phenomenon of wind and solar abandoning becomes more and more serious in the operation of power systems, and the microgrid is a new operating mode of power systems which provides a new consumption mode for wind power generation. With the increasingly close connection among energy resources and people’s increasing awareness of environmental protection, this paper establishes a microgrid optimal scheduling model with a combined heat and power system, in consideration of environmental costs. This model aims at the lowest comprehensive cost, at the same time taking into account the emission reductions of SO2 and NOx, considering the cost of power generated by the micro-generator, environmental cost, the related cost of battery, operation and maintenance cost of wind power, and photovoltaic power generation. The related constraints of thermal balance and power balance are also considered during microgrid system operation. The established model is solved with an improved particle swarm algorithm. At last, taking a microgrid system as an example, the validity and reliability of the proposed model are verified

The Antiperovskite‐Type Oxychalcogenides Ae3Q[GeOQ3] (Ae = Ba, Sr; Q = S, Se) with Large Second Harmonic Generation Responses and Wide Band Gaps

Abstract Oxychalcogenides capable of exhibiting excellent balance among large second‐harmonic generation (SHG) response, wide band gap (Eg), and suitable birefringence (Δn) are ideal materials class for infrared nonlinear optical (IR NLO) crystals. However, rationally designing a new high‐performance oxychalcogenide IR NLO crystal still faces a huge challenge because it requires the optimal orientations of the heteroanionic groups in oxychalcogenide. Herein, a series of antiperovskite‐type oxychalcogenides, Ae3Q[GeOQ3] (Ae = Ba, Sr; Q = S, Se), which were synthesized by employing the antiperovskite‐type Ba3S[GeS4] as the structure template. Their structures feature novel three‐dimensinoal frameworks constructed by distorted [QAe6] octahedra, which are further filled by [GeOQ3] tetrahedra to form antiperovskite‐type structures. Based on the unique antiperovskite‐type structures, the favorable alignment of the polarizable [GeOQ3] tetrahedra and distorted [QAe6] octahedra have been achieved. These contribute the ideal combination of large SHG response (0.7–1.5 times that of AgGaS2), wide Eg (3.52–4.10 eV), and appropriate Δn (0.017–0.035) in Ae3Q[GeOQ3]. Theoretical calculations and crystal structure analyses revealed that the strong SHG and wide Eg could be attributed to the polarizable [GeOQ3] tetrahedra and distorted [QAe6] octahedra. This research provides a new exemplification for the design of high‐performance IR NLO materials

Association between Small Intestinal Bacterial Overgrowth and Subclinical Atheromatous Plaques

Background: Several recent studies have reported the relationship between atherosclerosis and gut microbial imbalance. Small intestinal bacterial overgrowth (SIBO) is one of the most common forms of gut microbiota imbalance, and studies have shown that SIBO plays an important role in human health. However, the relationship between SIBO and subclinical atheromatous plaques remains unclear. The aim of this study was to investigate the frequency of subclinical atheromatous plaques in patients with SIBO and to explore the association between these two conditions. Methods: A total of 411 eligible subjects were included in this study. The lactulose hydrogen-methane breath test was used to diagnose SIBO, and ultrasound examinations of the carotid, abdominal aorta and lower extremity arteries were performed in all subjects to assess the presence of plaques. Results: Plaques were more common in the SIBO-positive group than in the SIBO-negative group (abdominal aorta, 74.2% vs. 38.8%, p p p p p = 0.004), OR = 1.81 (95% CI = 1.14–2.88, p = 0.011) and OR = 5.42 (95% CI = 2.78–10.58, p < 0.001) for abdominal, carotid, lower extremity and any-territory plaque presence. Conclusion: SIBO was found to be associated with subclinical atheromatous plaques, and the mechanism of this association warrants further exploration

Multi-Objective Economic Dispatch of Cogeneration Unit with Heat Storage Based on Fuzzy Chance Constraint

With the increasing expansion of wind power, its impact on economic dispatch of power systems cannot be ignored. Adding a heat storage device to a traditional cogeneration unit can break the thermoelectric coupling constraint of the cogeneration unit and meet the economic and stable operation of a power system. In this paper, an economy-environment coordinated scheduling model with the lowest economic cost and the lowest pollutant emissions is constructed. Economic costs include the cost of conventional thermal power generating units, the operating cost of cogeneration units, and the operating cost of wind power. At the same time, green certificate costs are introduced into the economic costs to improve the absorption of wind power. Pollutant emissions include SO2 and NOx emissions from conventional thermal power units and cogeneration units. The randomness and uncertainty of wind power output are fully considered, and the prediction error of wind power is fuzzy treated according to the fuzzy random theory, and the electric power balance and spinning reserve fuzzy opportunity conditions are established, which are converted into the explicit equivalent. The improved multi-objective particle swarm optimization (MOPSO) was used to solve the model. With this method, the validity of the model is verified by taking a system with 10 machines as an example

Graph Game Embedding

Graph embedding aims to encode nodes/edges into low-dimensional continuous features, and has become a crucial tool for graph analysis including graph/node classification, link prediction, etc. In this paper we propose a novel graph learning framework, named graph game embedding, to learn discriminative node representation as well as encode graph structures. Inspired by the spirit of game learning, node embedding is converted to the selection/searching process of player strategies, where each node corresponds to one player and each edge corresponds to the interaction of two players. Then, a utility function, which theoretically satisfies the Nash Equilibrium, is defined to measure the benefit/loss of players during graph evolution. Furthermore, a collaboration and competition mechanism is introduced to increase the discriminant learning ability. Under this graph game embedding framework, considering different interaction manners of nodes, we propose two specific models, named paired game embedding for paired nodes and group game embedding for group interaction. Comparing with existing graph embedding methods, our algorithm possesses two advantages: (1) the designed utility function ensures the stable graph evolution with theoretical convergence and Nash Equilibrium satisfaction; (2) the introduced collaboration and competition mechanism endows the graph game embedding framework with discriminative feature leaning ability by guiding each node to learn an optimal strategy distinguished from others. We test the proposed method on three public datasets about citation networks, and the experimental results verify the effectiveness of our method

Chiral and Polar Duality Design of Heteroanionic Compounds: Sr18Ge9O5S31 Based on [Sr3OGeS3]2+ and [Sr3SGeS3]2+ Groups

Abstract Chirality and polarity are the two most important and representative symmetry‐dependent properties. For polar structures, all the twofold axes perpendicular to the principal axis of symmetry should be removed. For chiral structures, all the mirror‐related symmetries and inversion axes should be removed. Especially for duality (polarity and chirality), all of the above symmetries should be broken and that also represents the highest‐level challenge. Herein, a new symmetry‐breaking strategy that employs heteroanionic groups to construct hourglass‐like [Sr3OGeS3]2+ and [Sr3SGeS3]2+ groups to design and synthesize a new oxychalcogenide Sr18Ge9O5S31 with chiral‐polar duality is proposed. The presence of two enantiomers of Sr18Ge9O5S31 is confirmed by the single‐crystal X‐ray diffraction. Its optical activity and ferroelectricity are also studied by solid‐state circular dichroism spectroscopy and piezoresponse force microscopy, respectively. Further property measurements show that Sr18Ge9O5S31 possesses excellent nonlinear optical properties, including the strong second harmonic generation efficiency (≈2.5 × AGS), large bandgap (3.61 eV), and wide mid‐infrared transparent region (≈15.3 µm). These indicate that the unique microstructure groups of heteroanionic materials are conducive to realizing symmetry‐breaking and are able to provide some inspiration for exploring the chiral‐polar duality materials

Efficacy of non-conventional synthetic DMARDs for patients with rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis

Objectives We conducted a systematic review and meta-analysis to determine the efficacy of non-conventional synthetic disease-modifying antirheumatic drug (ncs-DMARD) strategies on patients with rheumatoid arthritis (RA)-associated interstitial lung disease (ILD).Methods PubMed, EMBASE, the Cochrane Library and Web of Science were searched for relevant articles from inception to 1 June 2022. The results obtained from the analysis were expressed as mean difference (MD), effect size and 95% CI.Results A total of 17 studies, including 1315 patients with RA-ILD, were eligible. The ncs-DMARDs included abatacept, rituximab, tocilizumab, tumour necrosis factor and Janus kinase inhibitors. Compared with the baseline, there were no significant changes in forced vital capacity (FVC), forced expiratory volume in the first second (FEV1) and diffusion lung capacity for carbon monoxide (DLCO) values in the pooled data after ncs-DMARD treatment (alone or combined with conventional therapy) (p=0.36 for FVC; p=0.96 for FEV1 and p=0.46 for DLCO). Of note, FVC was obviously increased in rituximab subgroup (MD=−4.62, 95% CI −8.90 to −0.33, p=0.03). Also, high-resolution CT non-progression rate and fatality rate due to ILD progression in patients with RA-ILD were 0.792 (95% CI 0.746 to 0.834, p=0.015) and 0.049 (95% CI 0.035 to 0.065, p=0.000), respectively.Conclusion ncs-DMARDs alone or combined with conventional therapy might be an optimal and promising treatment for stabilising or improving ILD in patients with RA-ILD.PROSPERO registration number CRD42022356816

Add-on sirolimus for the treatment of mild or moderate systemic lupus erythematosus via T lymphocyte subsets balance

Objective The efficacy of sirolimus in treating severe or refractory systemic lupus erythematosus (SLE) has been confirmed by small-scale clinical trials. However, few studies focused on mild or moderate SLE. Therefore, in this study we elucidated clinical efficacy of add-on sirolimus in patients with mild or moderate SLE.Methods Data of 17 consecutive patients with SLE were retrospectively collected. SLE Disease Activity Index-2000 (SLEDAI-2K), clinical manifestation, laboratory data and peripheral T lymphocyte subsets with cytokines were collected before and 6 months after sirolimus add-on treatment. T cell subsets were detected by flow cytometry and cytokines were determined by multiplex bead-based flow fluorescent immunoassay simultaneously. Twenty healthy controls matched with age and sex were also included in our study.Results (1) The numbers of peripheral blood lymphocytes, T cells, T helper (Th) cells, regulatory T (Treg) cells, Th1 cells, Th2 cells and Treg/Th17 ratios in patients with SLE were significantly lower, while the numbers of Th17 cells were evidently higher than those of healthy control (p&lt;0.05). (2) After 6 months of sirolimus add-on treatment, urinary protein, pancytopenia, immunological indicators and SLEDAI-2K in patients with SLE were distinctively improved compared with those before sirolimus treatment (p&lt;0.05). (3) The numbers of peripheral blood lymphocytes, T cells, Th cells, Treg cells, Th2 cells and the ratios of Treg/Th17 in patients with SLE after treatment were clearly higher than those before (p&lt;0.05). (4) The levels of plasma interleukin (IL)-5, IL-6 and IL-10 in patients with SLE decreased notably, conversely the IL-4 levels increased remarkably compared with pretreatment (p&lt;0.05).Conclusions (1) Patients with SLE presented imbalanced T cell subsets, especially the decreased ratio of Treg/Th17. (2) Sirolimus add-on treatment ameliorated clinical involvement, serological abnormalities and disease activity without adverse reactions in patients with SLE. (3) The multi-target therapy facilitates the enhanced numbers of Treg cells, Treg/Th17 imbalance and anti-inflammatory cytokines, simultaneously, reducing inflammatory cytokines

On-ground demonstration of laser-link construction for space-based detection of gravitational waves

Laser acquisition and pointing system is subject to establish a 10 6 km magnitude inter-satellite laser link with root ultra-high pointing precision of 10 nrad/ Hz (1 mHz-1 Hz) in space-based gravitational wave detection missions. For the unprecedented challenge, a dedicated laser link construction scheme with three different detectors is proposed. After initial pointing with star trackers, CMOS/CCD cameras intend to suppress the laser pointing error to 1 grad . QPDs are subsequently used to achieve the final requirement. With various detectors and technologies, the scheme need intensive verification and study. We first design and build an on-ground laser link construction experimental system, which can simulate the whole process and recreate the actual critical working condition as realistic as possible by comprehensively considering the simulation of optical system, far field beam receiving characteristics and target precision. Results are well in agreement with the requirements and confirm the scheme under realistic conditions, which have not yet been fully tested experimentally