8 research outputs found
Visualization 1: Multilayer fluorescence imaging on a single-pixel detector
Visualization 1 Originally published in Biomedical Optics Express on 01 July 2016 (boe-7-7-2425
Visualization 2: Multilayer fluorescence imaging on a single-pixel detector
Visualization 2 Originally published in Biomedical Optics Express on 01 July 2016 (boe-7-7-2425
Visualization 2: Recovering higher dimensional image data using multiplexed structured illumination
Visualization 2 Originally published in Optics Express on 16 November 2015 (oe-23-23-30393
Pixel Super-Resolved Lensless on-Chip Sensor with Scattering Multiplexing
Lensless on-chip microscopy has shown great potential
for biomedical
imaging due to its large-area and high-throughput imaging capabilities.
By combining the pixel super-resolution (PSR) technique, it can improve
the resolution beyond the limit of the imaging detector. However,
existing PSR techniques are restricted by the feature size and crosstalk
of modulation components (such as spatial light modulator), which
cannot efficiently encode target information. Besides, the reconstruction
algorithms suffer from the trade-off between reconstruction quality,
imaging resolution, and computational efficiency. In this work, we
constructed a novel integrated lensless on-chip sensor via scattering
multiplexing and reported a robust PSR algorithm for target reconstruction.
We employed a scattering layer to replace conventional modulators
and permanently integrated it with the image detector. Benefiting
from the high-degree-of-freedom calibration, the scattering layer
realized fine wavefront modulation with a small feature size. Besides,
the integration engineering avoided repetitious calibration and reduced
the complexity of data acquisition. The reported PSR algorithm combined
both model-driven and data-driven strategies, with the advantages
of high fidelity, strong generalization, and low computational complexity.
The remarkable performance allows it to efficiently exploit the high-frequency
information from the fine modulation. A series of experiments validate
that the reported sensor and PSR algorithm provide a low-cost solution
for large-scale microscopic imaging, realizing ∼1.1 μm
imaging resolution and ∼7 dB enhancement on the PSNR index
compared to existing methods
Analysis of potential factors predicting symptomatic intracranial hemorrhage (sICH) at day 1.
<p>Analysis of potential factors predicting symptomatic intracranial hemorrhage (sICH) at day 1.</p
Data of mechanical thrombectomy with Solitaire.
<p>Data of mechanical thrombectomy with Solitaire.</p
Factors distributed between female and male.
<p>Factors distributed between female and male.</p
Analysis of potential factors predictive of mortality at 3 months.
<p>Analysis of potential factors predictive of mortality at 3 months.</p