The process of article search and selection.

<p><i>From</i>: Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009). <i>P</i>referred <i>R</i>eporting <i>I</i>terns for <i>S</i>ystematic Reviews and <i>M</i>eta-<i>A</i>nalyses: The PRISMA Statement. PLoS Med 6(6): e1000097. doi:<a href="https://doi.org/10.1371/joumal.pmed1000097" target="_blank">10.1371/joumal.pmed1000097</a>. <b>For more information, visit</b><a href="http://www.prisma-statement.org" target="_blank">www.prisma-statement.org</a><b>.</b></p

Funnel plot of publication bias.

<p>Funnel plot of publication bias.</p

Characteristics of included articles.

<p>Characteristics of included articles.</p

Stratified analyses of association between the genotypes and risk of essential hypertension in the obese and the non-obese participants.

<p>ORs adjusted for gender, age, body mass index, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, serum triglyceride levels, plasma glucose level, smoking habits and drinking habits. OR, odds ratio; CI, confidence interval; SNP, single-nucleotide.</p><p>*ORs adjusted for gender was not performed in sub-group analyses of Male and Female.</p><p>P-value for the interaction between A46G genotype and body mass index on hypertension was 0.010.</p

Characteristics of study participants.

<p>SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; Glu, glucose; Cr, creatinine; ALT, alanine aminotransferase; HR, heart rate.</p><p>Values are mean±SD.</p><p>NS indicates not significant.</p

The frequencies of the β2-adrenergic receptor gene C-47T, A46G and C79G polymorphisms genotypes.

<p>*P value of the comparison of the additive genetic model using the generalized linear model.</p><p>**P value of the comparison of allelic frequencies.</p

Haplotype analyses of the β2-adrenergic receptor gene polymorphisms in hypertension and control subjects.

<p>All haplotypes with frequency greater than 1% detected in the haplotype analyses are shown in the table.</p><p>HS test, haplotype specific testing; OR, odds ratio; CI, confidence interval.</p>a<p>P values and OR values derived from comparing of a specific haplotype with the other two.</p>b<p>P values and OR values derived from comparing each haplotype with the base-line haplotype (T-A-C).</p>c<p>P value for global test comparing model with haplotypes to model without.</p

The genotype distributions and allele frequencies of the β2-adrenergic receptor gene C-47T, A46G and C79G polymorphisms in obese and non-obese.

<p>The genotype distributions and allele frequencies of the β2-adrenergic receptor gene C-47T, A46G and C79G polymorphisms in obese and non-obese.</p

Linkage disequilibrium (LD) block defined by the Haploview program based on the confidence interval method.

<p>a represents LD measure of D'. b represents LD measure of r².</p