Model independent analysis of top quark forward-backward asymmetry at the Tevatron up to \mathcal{O}(\as^2/\Lambda^2)

We present the complete calculations of the forward-backward asymmetry ($A_{\rm FB}$) and the total cross section of top quark pair production induced by dimension-six four quark operators at the Tevatron up to \mathcal{O}(\as^2/\Lambda^2). Our results show that next-to-leading order (NLO) QCD corrections can change $A_{\rm FB}$ and the total cross section by about 10%. Moreover, NLO QCD corrections reduce the dependence of $A_{\rm FB}$ and total cross section on the renormalization and factorization scales significantly. We also evaluate the total cross section and the charge asymmetry ($A_{\rm C}$) induced by these operators at the Large Hadron Collider (LHC) up to \mathcal{O}(\as^2/\Lambda^2), for the parameter space allowed by the Tevatron data. We find that the value of $A_{\rm C}$ induced by these operators is much larger than SM prediction, and LHC has potential to discover these NP effects when the measurement precision increases.Comment: 25 pages, 10 figures; final version in PR

The State-of-the-Art Practices of the Internet Banking in Taiwan

This paper reports an investigation into the state-of-the-art practices of Internet banking in Taiwan. Emphasis is focused on the adoption of security technology. Three kinds of security utilities—SSL, SET, and Non-SET—are compared in terms of risks and supported functions. The author also analyzes factors that influence the development of Internet banking. The Ministry of Finance of the Taiwanese government has adopted a policy that fosters the development of Internet banking. However, understanding security technologies demands in-depth expert knowledge, and goes beyond the capacity of general citizens. The authors suggest that the first priority is given to the authority’s promulgation of laws and guidelines. Second, the banking industry needs to integrate the security mechanisms of Internet banking services with the existing environment. Finally, a risk allotment policy would help to remove fear and doubt from customer’s minds

Development of a universal plate-agglutination test for detecting Haemophilus parasuis

Due to the serovar diversity in Haemophilus (H.) parasuis, it is difficult to develop a universal serological method for detection of this pathogen. Here, we report a universal plate-agglutination test for detecting H. parasuis. Diagnostic antisera were prepared by mixing antisera of serovars 4, 5, 12, 13 and 14 in the optimized ratio. The results of the plate-agglutination test showed that the diagnostic antisera could agglutinate with all 15 reference strains of H. parasuis and 74/75 clinical isolates. Further, the specificity of the method was validated with 22 bacterial strains from 12 related species

Effect of Weight-Reduction in Obese Mice Lacking Toll-Like Receptor 5 and C57BL/6 Mice Fed a Low-Fat Diet

Background. This study aims to investigate the effect of feeding low-fat diet (LFD) to diet-induced obesity (DIO) mice lacking TLR5 (TLR5−/−), which have a tendency to develop glucose intolerance with increased adiposity, compared to that in C57BL/6 mice. Results. TLR5−/− and C57BL/6 male mice were divided into three subgroups: (1) control, mice were fed a standard AIN-76A (fat: 11.5 kcal%) diet for 12 weeks; (2) DIO, mice were fed a 58 kcal% high-fat diet (HFD) for 12 weeks; and (3) diet, mice were fed a HFD for 8 weeks to induce obesity and then switched to a 10.5 kcal% LFD for 4 weeks. The glucose intolerance in DIO TLR5−/− mice was more significant than that in DIO C57BL/6 mice and was not attenuated by a switch to the LFD. Weight-reduction with LFD had significantly decreased the epididymal fat mass in C57BL/6 mice but not in TLR5−/− mice. In addition, the LFD-fed TLR5−/− mice showed significantly higher expression of ghrelin in the serum and resistin in the epididymal fat than that in C57BL/6 mice. Conclusions. This study demonstrated that TLR5 gene knockout impairs some effects of weight-reduction in DIO

Senescence marker protein 30 in acute liver failure: validation of a mass spectrometry proteomics assay

<p>Abstract</p> <p>Background</p> <p>Our previous proteomic study showed that the senescence marker protein (SMP30) is selectively present in the plasma of a murine model of acute liver failure (ALF). The aim of this study was to validate this SMP30 expression in the plasma and liver tissues of mice and humans with ALF.</p> <p>Methods</p> <p>After the proteomic analysis of plasma from a murine model of D-galactosamine/lipopolysaccharide (GalN/LPS)-induced ALF by two-dimensional electrophoresis (2-DE) and mass spectrometry, the expression levels of SMP30 in the plasma and liver tissues were validated by western blot and RT-PCR analyses. These results were then confirmed in plasma samples from humans.</p> <p>Results</p> <p>These data validate the results of 2-DE, and western blot showed that SMP30 protein levels were only elevated in the plasma of ALF mice. Further analysis revealed that GalN/LPS induced the downregulation of SMP30 protein levels in liver tissues (by approximately 25% and 16% in the GalN/LPS-treated mice and in the treated mice that survived, respectively; <it>P </it>< 0.01). Hepatic SMP30 mRNA levels decreased by about 90% only in the mice that survived the GalN/LPS treatment. Importantly, plasma obtained from patients with ALF also contained higher levels of SMP30, about (3.65 ± 0.34) times those observed in healthy volunteers.</p> <p>Conclusion</p> <p>This study shows that SMP30 is not only a potential biomarker for the diagnosis and even prognosis of ALF. It also plays a very important role in a self-protective mechanism in survival and participates in the pathophysiological processes of ALF.</p