A prospective observational study for the effect of vaginal pH on dinoprostone gel for cervical ripening/labor induction

BACKGROUND: To observe if vaginal pH has any effect on the efficacy of dinoprostone /PGE2 gel commonly used for cervical ripening / labor induction in post-term patients. Study Design: Prospective observational study. Period of Study: 1 (one year). Place of Study: Govt. Institute of Social Obstetrics and Kasturba Gandhi Hospital for women and children. METHODS: A prospective study was conducted in 100 women in labour ward who were admitted for induction of labor. Vaginal pH and preinduction Bishops score measured before inducing the labor using dinoprostone gel. Bishops score was measured after 6 hour to assess any change in score; the outcome of the gel induction is also assessed by number of vaginal deliveries, induction to vaginal delivery interval. Association between vaginal pH and age, parity, draining PV is also studied. RESULTS: This study showed a statistically significant association between higher vaginal pH and change in Bishops score after 6 hours from the pre-induction Bishops score. At higher pH >4.5, if PGE2 gel induction is done there is more chance of vaginal delivery than at lower pH<4.5. Also in case of pre-labour rupture of membrane who presented with draining per vagina, they have more chance of high vaginal pH, so PGE2 gel induction on these patients also showed higher number of vaginal deliveries. In this study, we have also seen that at higher pH after PGE2 gel induction the time from induction to vaginal delivery has also shortened significantly (within 12 hours). No association has been found between vaginal pH with age and parity. CONCLUSION: Vaginal pH can be an important parameter in predicting the success of PGE2 gel induction in achieving successful vaginal deliveries

A Study Of The Mechanism Of Inactivation Of Anti-hapten Antibody By Cobalt-60 Gamma-radiation.

PhDMicrobiologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/185761/2/6305016.pd

Comparison of Phacotrabeculectomy and Phacotrabeculectomy with Subconjunctival 5-Fluorouracil

Introduction: Glaucoma is the second leading cause of blindness worldwide. Phacotrabeculectomy is a technique in which glaucoma and cataract surgery performed. &#13; Methods: Prospective study was carried out in the department of glaucoma at Lumbini Eye Institute, Bhairahawa.100 patients who underwent phacotrabeculectomy within a period of two years. Patients were divided into two groups those who received 5FU (n=47) and no antifibrotic agent (n= 53). &#13; Results: The age range was from 38 to 80 years; mean age of 62.97±9.14 SD. 55% were male and 45% were female.The postoperative IOP reduction in last follow- up group A was mean=13.08±1.57SD and mean=13.23±1.73SD in group B. This was statically significant with P &lt;0.001. Bleb survival was almost similar in two groups 3.17(78.31%) in group A and 3.20 (78.93%) in group B. 85% visual acuity was improved in both groups. &#13; Conclusions: Phacotrabeculectomy and phacotrabeculectomy with inj. 5FU, both were equally effective surgical techniques in terms of visual acuity, IOP control and bleb survival.There was no significant statistical difference vis-à-vis the success of Phacotrabeculectomy using of either these two techniques. &#13; Keywords: glaucoma; 5FU; intraocular pressure; phacotrabeculectomy

Scleral Fixation of Intraocular Lens with Ab Interno Technique

Introduction: Implantation of scleral fixation intraocular lens for the surgical management of aphakia cases without capsular support is a safe procedure. Methods: Prospective study was carried out at Lumbini Eye Institute, Bhairahawa. A total of 32 patients underwent scleral fixation intraocular lens implantation within a period of two years from February 2014 to February 2016. Results: The age range was from 15 to 79 years; mean age was 47.56±20.16 SD. Among them 14 (43.75%) were male and 18 (56.25%) were female. The follow-up lasted for 24 months. The postoperative characteristics of the patients are listed in the tables below. Conclusions: SFIOL for the surgical management of aphakia in the absence of capsular support is a safe procedure. The long-term follow-up is needed for an accurate evaluation of outcomes. Keywords: double armed prolene suture; intraocular pressure; scleral fixation intraocular lens; scleral tunnel. [PubMed

Impact of Futuristic Climate Variables on Weed Biology and Herbicidal Efficacy: A Review

Our changing climate will likely have serious implications on agriculture production through its effects on food and feed crop yield and quality, forage and livestock production, and pest dynamics, including troublesome weed control. With regards to weeds, climatic variables control many plant physiology functions that impact flowering, fruiting, and seed dormancy; therefore, an altered climate can result in a weed species composition shift within agro-ecosystems. Weed species will likely adapt to a changing climate due to their high phenotypic plasticity and vast genetic diversity. Higher temperatures and CO2 concentrations, and altered moisture conditions, not only affect the growth of weeds, but also impact the effectiveness of herbicides in controlling weeds. Therefore, weed biology, growth characteristics, and their management are predicted to be affected greatly by changing climatic conditions. This manuscript attempted to compile the available information on general principles of weed response to changing climatic conditions, including elevated CO2 and temperature under diverse rainfall patterns and drought. Likewise, we have also attempted to highlight the effect of soil moisture dynamics on the efficacy of various herbicides under diverse agro-ecosystems

Engineered Deinococcus radiodurans R1 with NiCoT genes for bioremoval of trace cobalt from spent decontamination solutions of nuclear power reactors

International audienc

Discerning morpho-anatomical, physiological and molecular multiformity in cultivated and wild genotypes of lentil with reconciliation to salinity stress

<div><p>One hundred and sixty two genotypes of different <i>Lens</i> species were screened for salinity tolerance in hydroponics at 40, 80 and 120 mM sodium chloride (NaCl) for 30 d. The germination, seedling growth, biomass accumulation, seedling survivability, salinity scores, root and shoot anatomy, sodium ion (Na⁺), chloride ion (Cl^-) and potassium ion (K⁺) concentrations, proline and antioxidant activities were measured to evaluate the performance of all the genotypes. The results were compared in respect of physiological (Na⁺, K⁺ and Cl^-) and seed yield components obtained from field trials for salinity stress conducted during two years. Expression of salt tolerance in hydroponics was found to be reliable indicator for similarity in salt tolerance between genotypes and was evident in saline soil based comparisons. Impressive genotypic variation for salinity tolerance was observed among the genotypes screened under hydroponic and saline field conditions. Plant concentrations of Na⁺ and Cl^- at 120 mM NaCl were found significantly correlated with germination, root and shoot length, fresh and dry weight of roots and shoots, seedling survivability, salinity scores and K⁺ under controlled conditions and ranked the genotypes along with their seed yield in the field. Root and shoot anatomy of tolerant line (PDL-1) and wild accession (ILWL-137) showed restricted uptake of Na⁺ and Cl^- due to thick layer of their epidermis and endodermis as compared to sensitive cultigen (L-4076). All the genotypes were scanned using SSR markers for genetic diversity, which generated high polymorphism. On the basis of cluster analysis and population structure the contrasting genotypes were grouped into different classes. These markers may further be tested to explore their potential in marker-assisted selection.</p></div