12 research outputs found
Figure S3 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Figure S3 displays the Validation of the association effect of rs6757077 at IKZF2 using data from six independent study sites in China.</p
Supplementary Table S8 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S8 displays the sample size from independent Asian studies.</p
Supplementary Table S5 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S5 shows the signals for the variants in stratified analysis by smoking behavior</p
Supplementary Table S3 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S3 shows the signals at rs7985487 in Firth test validation.</p
Figure S4 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Figure S4 shows the results of eQTL analysis of rs968516 in GTEx.</p
Supplementary Table S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S1 displays the number of ever- and never-smokers from each of the ten studies.</p
Supplementary Table S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S2 shows the signals at known susceptibility loci from ever- and never-smoking lung cancer.</p
Supplementary Table S7 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S7 shows the signals from interaction with smoking status for the identified variants in lung cancer.</p
Figure S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Figure S1 displays the distribution of histology subtypes in each population in ever- and never-smokers.</p
Supplementary Table S6 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
- Author
- Adonina Tardon (14950471)
- Angela Cox (17969731)
- Angela Risch (14950483)
- Angeline S. Andrew (17079297)
- Ann G. Schwartz (14951505)
- Chao Cheng (11149791)
- Christopher I. Amos (14934645)
- Chu Chen (17969704)
- Colette Gaba (18084786)
- David C. Christiani (14950465)
- Demetrios Albanes (18084753)
- Diptasri Mandal (18084780)
- Gad Rennert (14932691)
- Gail F. Fernandes (18084741)
- Gary E. Goodman (18084762)
- Geoffrey Liu (9416973)
- H-Erich Wichmann (17969713)
- Heike Bickeböller (17969710)
- Hongbing Shen (13817299)
- Ivan Gorlov (18084774)
- James C. Willey (18084783)
- James D. McKay (18084750)
- Jianrong Li (18084738)
- Jinyoung Byun (17079480)
- Joan E. Bailey-Wilson (14935133)
- John K. Field (14950474)
- Jun Xia (18084789)
- Kjell Grankvist (17969725)
- Kristen S. Purrington (18084777)
- Lambertus A. Kiemeney (14932649)
- Loïc Le Marchand (15849085)
- Maria T. Landi (18084756)
- Matthew B. Schabath (14950486)
- Mattias Johansson (14950468)
- Melinda C. Aldrich (14950480)
- Meng Zhu (14953086)
- Michael P.A. Davies (18084765)
- Mikael Johansson (14949436)
- Neil E. Caporaso (17969728)
- Paul Brennan (14943829)
- Philip Lazarus (17969740)
- Ping Yang (14951499)
- Rayjean J. Hung (14943811)
- Ryan Sun (18084768)
- Sanjay Shete (14963475)
- Shanbeh Zienolddiny (18084771)
- Shannon E. Slewitzke (18084744)
- Stephen Lam (17969701)
- Stig E. Bojesen (17969707)
- Susan M. Pinney (14951508)
- Susan M. Rosenberg (18084747)
- Susanne M. Arnold (18084759)
- Xiangjun Xiao (18084735)
- Yafang Li (18084732)
- Yanhong Liu (14963430)
- Yohan Bossé (9633060)
- Younghun Han (17079435)
- Yun-Chul Hong (17969734)
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Supplementary Table S6 displays epigenomic evidence for the variants being located within genomic regions associated with regulatory activity.</p