Remaking “Women” and Contemporary Chinese Feminism——Based on The Question of Women in Chinese Feminism

The Question of Women in Chinese Feminism gives an historical retrospective of China in the past 100 years with a 20th century global perspective, probes about in-depth and multi-level Chinese women and contemporary social problems by tracing the evolution of the left-wing ideological context, and elaborates on the remaking of “women” creatively by virtue of the historical heritage of socialism. It is of great significance in responding to new changes and new issues taking place in contemporary Chinese feminism. For instance, in today’s China, while analyzing gender equality, people have to focus not only on the relationship between the sexes, but on development within women’s groups and on relations among class/strata also. Therefore, remaking “women” and how to remake “women”, in the Chinese context today, are important issues to feminists, as they will tell, to a certain extent, if gender studies can effectively respond to social issues in contemporary China. 

Effects of Heating and Liquid Nitrogen on Mechanical Characteristics and Rockburst Characteristics of Granite

Due to the depletion of shallow resources and the reduction of the space for human life and development, in recent years, human beings began to gradually expand to the deep underground. The increase of development depth will bring a series of safety problems, so it is particularly important to study and deal with rockburst. In this paper, based on laboratory tests, relevant literature, and research at home and abroad, the TAWD-2000 electrohydraulic servo rock mechanics testing machine and PIC-2 acoustic emission (AE) testing system are used. Uniaxial compression tests and AE monitoring tests were carried out on granite samples to analyze the property and AE characteristic parameters of granite under the action of liquid nitrogen (LN2) and to further study the fracture mode of granite. The following conclusions can be obtained: the LN2 cooling has a deterioration influence on the strength of rock, and the elastic modulus and peak stress of granite show a downward trend with the increasing number of cycles. With the cycle times of LN2 actions increasing, the AE ring count of granite and the frequency and amplitude of energy in each stage have an upward trend. When the rock reaches the failure stage, the energy at the catastrophe point increases, and the ring count also increases sharply. The RA-AF diagram of AE parameters can characterize two failure modes of rock, tensile failure and shear failure. In the process of fracture of granite samples, shear cracks dominate, leading to shear failure or compression failure of granite. Based on the method of elastic energy, the tendency index of rockburst of granite samples under different working conditions is calculated. The tendency of rockburst decreases with the decrease of elastic modulus. Under the repeated action of LN2, the tendency of rockburst of granite samples presents a downward trend, and the action of LN2 reduces the probability of rockburst to a certain extent

Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

Abstract Gliomas are the most common malignant primary brain tumors in adults with poor prognoses. The purpose of this study is to explore CACNG3 as a prognostic factor that is closely related to the progression and survival outcome of gliomas and to provide a potential new molecular target for the diagnosis and treatment of glioma patients. CACNG3 expression and related clinical data were collected from three major databases of The Chinese Glioma Genome Atlas (CGGA), The Cancer Genome Atlas (TCGA), and Gene Expression Omnibus (GEO). The CGGA dataset was used as a training set, and TCGA and GEO datasets obtained from the GEO database were used for validation. CACNG3 was expressed at low levels in the tumor group, and the overall survival (OS) in patients with low CACNG3 expression is shorter. Furthermore, CACNG3 expression was negatively associated with glioma grades, which was confirmed in the IHC results of clinical samples. The expression level of CACNG3 in the IDH1 wide-type group, 1p/19q non-codel group, and mesenchymal subtype group was significantly reduced, and the results showed that CACNG3 could serve as a biomarker for the mesenchymal molecular subtype. In addition, the univariate and multivariate analysis verified the prognostic value of CACNG3 in predicting the OS of gliomas of all grades. The results of functional annotation and pathway enrichment analysis of differently expressed genes(DEGs), showed that CACNG3 might affect the development of glioma by interfering with synaptic transmission. Moreover, temozolomide (TMZ), commonly used in the treatment of glioma, increased CACNG3 expression in a dose and time-dependent manner. Therefore, CACNG3 plays a vital role in the occurrence and development of gliomas and can serve as a potential biomarker for targeted therapy and further investigation in the future

Additional file 3 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 2 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 5 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 4 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 1 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 7 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Additional file 6 of Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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