Comparison of SUV_max at index esophageal locations among 130 subjects with complete RDQ.

<p>Subjects were stratified by the presence of endoscopic erosive disease and gastroesophageal reflux symptoms. Abbreviation: FDG, ¹⁸F-Fluorodeoxyglucose; SUV_max, maximum of standardized uptake values; EE, erosive esophagitis; NE, non-erosive; RDQ, Reflux Disease Questionnaire; UES, upper esophageal sphincter; ME, middle esophagus; EGJ, esophagogastric junction. Data are presented as mean ± standard deviation (*<i>P</i><.05, **<i>P</i><.01, Student <i>t</i> test).</p

FDG PET/CT images from an 84-year-old male with erosive esophagitis (Los Angeles classification grade A).

<p>PET/CT showed two focal areas of FDG accumulation in the middle esophagus (thin arrow on sagittal view, SUV_max = 4.5) and at the esophagogastric junction (thick arrows, SUV_max = 6.9).</p

FDG PET/CT images from a 59-year-old male with Barrett's esophagus.

<p>PET/CT showed intense FDG accumulation with correlative wall thickening in the esophagogastric junction (cursor, SUV_max = 5.6).</p

Comparison of SUVmax of FDG at index upper gastrointestinal locations.

a.<p>Data are presented as mean ± standard deviation deviation (median, interquartile range) or number (percentage).</p>b.<p>Abbreviation: FDG, 18F-Fluorodeoxyglucose; SUVmax, maximum of standardized uptake values.</p>c.<p>Mild esophagitis refers to erosive esophagitis, LA Grade A+B; severe esophagitis refers to erosive esophagitis, LA Grade C+D.</p><p>*<i>P</i><0.05 indicates statistical significance.</p

Determinants of esophageal inflammation (SUV_max) at index esophageal locations.

a.<p>Multiple linear stepwise regression analysis was performed using the SUV_max as a dependent variable and the independent variables of those variables with significant correlation.</p>b.<p>Abbreviation: BMI, body mass index; SUV_max, maximum of standardized uptake values.</p>c.<p>*<i>P</i><0.05 indicates statistical significance.</p

Basic demographics and SUV_max of FDG at index upper gastrointestinal locations.

a.<p>Data are presented as mean ± standard deviation (median, interquartile range) or number (percentage).</p>b.<p>Abbreviation: FDG, ¹⁸F-Fluorodeoxyglucose; EE, erosive esophagitis; LA, Los Angeles classification system; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HOMA-IR, Homeostasis Model of Assessment-Insulin Resistance; BMI, body mass index; RDQ, Reflux Disease Questionnaire; SUV_max, maximum of standardized uptake values.</p>c.<p>*<i>P</i><.05, indicates statistical significance.</p