REMOTE EDUCATION INCREASES COMPETITIVE ENVIRONMENT OF TERTIARY EDUCATION IN THE REPUBLIC OF UZBEKISTAN

For many years remote education mostly was meant for correspondence courses, due to the pandemic situation caused by COVID-19, it has become the only types of education for some time. In the article ways of offering learning materials, online delivery of courses, as well as, merits and demerits of remote education was discussed. The role of remote education in the education system of the Republic of Uzbekistan, which increases the competitiveness of the service, was also stated in the article

Estimation procedure of industrial-engineering communication (IEC)

© Medwell Journals, 2016.This study has summarized some aspects of industrial-engineering communication estimation procedure. It has shown up faults of such effectiveness research methods as industrial analysis ratio forming part of the communication, game theory, input-output balancing. There has been proved the method industrial-engineering communication estimation procedure. The method consists of qualitative analysis of industrial-engineering communication and its effect on the level of transaction cost and enterprises value, effectiveness of such communication from the view of social and infrastructural development. Mathematical method is based on the functional analysis and calculating the flexibility of transaction cost function which are formed in the result of the industrial-engineering communication development

Concept of development of an entrepreneurial culture in the hospitality industry enterprises of the Republic of Tatarstan

This paper presents the role of an entrepreneurial culture in the management system to improve the efficiency of the hotel business enterprises in Tatarstan. Currently, the Republic of Tatarstan has become one of the most attractive tourist destinations not only in Russia, but also abroad, that certainly confirms the relevance of this study. Popular hotels of the city of Kazan: "Shalyapin Palace Hotel", "Safar-Hotel" and "Regina" were made the objects of the study. Survey and subsequent analysis of its data used in the capacity of a research method. It was revealed that the organizational culture as an institutional framework of modern business is characterized by focusing on maximum customer satisfaction, innovations, productivity, independence and entrepreneurial attitude, quality, labor and product safety, and customization. Based on substantiation of the motivational mechanism for development of organizational culture in hospitality industry enterprises, we have developed an adaptive strategy of organizational culture "implantation" into a company of hospitality industry that shapes the entrepreneurial style of behavior, initiates staff efforts to achieve final results and the efficiency with feedback system. Practical application of the developed strategy enhances the effectiveness of labor efforts of hospitality industry enterprise employees

Coumarins of Peucedanum baicalense and cytotoxic activity of some isolated coumarins

DOI: http://dx.doi.org/10.5564/mjc.v13i0.155 Mongolian Journal of Chemistry Vol.13 2012: 23-2

The influence of the substituent [PhNHNH- and EtN(NH2)-] on the N-thiophosphorylated thiosemicarbazides RC(S)NHP(S)(OiPr)2 crystal design

Two N-thiophosphorylated thiosemicarbazides of the common formula RC(S)NHP(S)(OiPr)2 [R = PhNHNH- (1); EtN(NH2)- (2)] have been synthesized and characterized by IR, 1H and 31P spectroscopy, and the single crystal X-ray diffraction method. Single crystal X-ray diffraction studies showed the thiosemicarbazides form both intra- and intermolecular hydrogen bonds, which in turn lead to polymeric chain formation. Moreover, according to the X-ray data of the phenylsubstituted thiosemicarbazide, the formation of intermolecular H⋯η6-phenyl interactions were established. © 2008 Elsevier Ltd. All rights reserved

New bifunctional N-thiophosphorylated thiourea and 2,5-dithiobiurea derivatives. Crystal structures of R[C(S)NHP(S)(OiPr)2]2 (R = -N(Ph)CH2CH2N(Ph)- and -NHNH-)

A new bifunctional N-thiophosphorylated thiourea and 2,5-dithiobiurea of the common formula R[C(S)NHP(S)(OiPr)2]2 [R = -N(Ph)CH2CH2N(Ph)- (H2La); -NHNH- (H2Lb)] have been synthesized and characterized by IR, 1H, 31P spectroscopy and the single crystal X-ray diffraction method. The structure of the latter compound in CDCl3 and acetone-d6 solutions has been discussed in comparison with the monofunctional thiosemicarbazide PhNHNHC(S)NHP(S)(OiPr)2 (HLc). © 2008 Elsevier Ltd. All rights reserved

Why can the Diels-Alder reaction of 9,10-diphenylanthracene with 4-phenyl-1,2,4-triazoline-3.5-dione pass by an abnormal way?

9,10-Diphenylanthracene reacts with dienophile by 1,4-positions rather than 9,10-ones of trivial anthracenes, that has been justified with estimation of kinetic and thermodynamic parameters of the process. © 2013 Mendeleev Communications. All rights reserved

Homo-Diels-Alder reaction of a very inactive diene, bicyclo[2,2,1]hepta-2, 5-diene, with the most active dienophile, 4-phenyl-1,2,4-triazolin-3,5-dione. Solvent, temperature, and high pressure influence on the reaction rate

Solvent, temperature, and high pressure influence on the rate constant of homo-Diels-Alder cycloaddition reactions of the very active hetero-dienophile, 4-phenyl-1,2,4-triazolin-3,5-dione (1), with the very inactive unconjugated diene, bicyclo[2,2,1]hepta-2,5-diene (2), and of 1 with some substituted anthracenes have been studied. The rate constants change amounts to about seven orders of magnitude: from 3.95.10-3 for reaction (1+2) to 12200 L mol-1 s-1 for reaction of 1 with 9,10-dimethylanthracene (4e) in toluene solution at 298 K. A comparison of the reactivity (ln k2) and the heat of reactions (r-nH) of maleic anhydride, tetracyanoethylene and of 1 with several dienes has been performed. The heat of reaction (1+2) is -218 ± 2 kJ mol-1, of 1 with 9,10-dimethylanthracene -117.8 ± 0.7 kJ mol-1, and of 1 with 9,10-dimethoxyanthracene -91.6 ±0.2 kJ mol-1. From these data, it follows that the exothermicity of reaction (1+2) is higher than that with 1,3-butadiene. However, the heat of reaction of 9,10- dimethylanthracene with 1 (-117.8 kJ mol-1) is nearly the same as that found for the reaction with the structural C=C counterpart, N-phenylmaleimide (-117.0 kJ mol-1). Since the energy of the N=N bond is considerably lower (418 kJ/bond) than that of the C=C bond (611 kJ/bond), it was proposed that this difference in the bond energy can generate a lower barrier of activation in the Diels-Alder cycloaddition reaction with 1. Linear correlation (R = 0.94) of the solvent effect on the rate constants of reaction (1+2) and on the heat of solution of 1 has been observed. The ratio of the volume of activation (V≠) and the volume of reaction (V r-n) of the homo-Diels-Alder reaction (1+2) is considered as "normal": V≠/Vr-n = -25.1/-30.95 = 0.81. Copyright © 2012 John Wiley & Sons, Ltd

Studying the effect of high pressure on the cycloaddition reactions of maleic anhydride and substituted anthracenes

The kinetics (rate, activation, and volume) of the high-pressure (up to 2500 bar) Diels-Alder reactions of maleic anhydride with 9-phenylanthracene and 9,10-dimethylanthracene in toluene is investigated. © 2013 Pleiades Publishing, Ltd

Gene transfer using new complexes between cardiolipin-like dicationic lipids and plasmid DNA to tumor cells

The lipid vesicles of bisamphiphiles cardiolipin-like dicationic lipids (CDL) I-IV were studied for creation of lipoplexes with plasmid DNA of different sizes to obtain stable lipoplexes for gene transfer to gene therapy. Lipoplexes' sizes (300±100 nm) and stablity (> 2 hrs) of CDL were sufficient to be used in gene transfer against monolayer and suspension cell cultures. The CDL total cytotoxicity determined by MTT-test was lower compare to lipofectin as a control. Transfection conditions against tumor cells lines were optimized by lipoplexes of CDL and plasmid DNA. The most efficient transfection for lipoplexes CDL-plasmid DNA was at the lipid-DNA (L/D) ratio equal to 5 (for lipofectin, it was 2). For monolayer cell cultures, lipoplexes CDL-I are comparable in terms of transfection efficacy with lipofectin; in the case of suspension culture, their efficiency was lower by one order of magnitude. It permits a usage of lipoplexes suggested as mediators for gene transfer and delivery to human tumor cells