Effect of taurine pre-treatment on KBrO₃-induced changes in some parameters of oxidative stress in intestinal homogenates.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in some parameters of oxidative stress in intestinal homogenates.</p

Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of enzymes of carbohydrate metabolism in intestinal homogenates.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of enzymes of carbohydrate metabolism in intestinal homogenates.</p

Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of BBM enzymes in isolated BBMV.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of BBM enzymes in isolated BBMV.</p

DNA fragmentation in intestinal mucosal homogenates determined by diphenylamine assay.

<p>Results are mean ±SEM of 6 different preparations. * Significantly different at <i>p</i>< 0.05 from control. † Significantly different at p < 0.05 from KBrO₃-treated group. ǂ Significantly different at p < 0.05 from KBrO₃ treated group</p

Histology of hematoxylin and eosin stained sections of rat intestine (duodenum section).

<p>Duodenum in the untreated control (A) shows normal epithelia of both villi and intestinal glands whereas KBrO₃ treated group (B) reveals extensive damage of both components with the lumen being filled with debris. The taurine alone group (C) shows reasonably well preserved condition of both components while taurine+KBrO₃ treated group (D) shows resumption in the morphology of both villi and intestinal glands. Intestinal villi are shown by black arrow and intestinal crypts by green arrow. Magnification is 200 X, scale bar [−] = 50 μm.</p

Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of BBM enzyme in the intestinal homogenates.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of BBM enzyme in the intestinal homogenates.</p

Chemoprotective effects of taurine on KBrO₃ induced alterations in intestinal cell metabolism, membrane integrity and oxidative stress: a summary.

<p>AO: antioxidant; BBM: brush border membrane; DPC: DNA-protein cross-links; KBr: potassium bromide; KBrO₃: potassium bromate; ROS: reactive oxygen species; SH: sulfhydryl; T: taurine.</p

Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of ACP and total ATPase in intestinal homogenates.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in the activities of ACP and total ATPase in intestinal homogenates.</p

Comet assay of intestinal mucosal cells to assess the degree of DNA breakage.

<p>(A) Mucosal cells were subjected to alkaline single cell gel electrophoresis (comet assay) and visualized under a fluorescent microscope after staining the DNA with ethidium bromide. I: Control; II: KBrO₃ alone; III: taurine alone; IV: taurine+KBrO₃. (B) Comet tail lengths. The results of comet assay in panel (A) are represented as mean values of tail lengths. *Significantly different at p < 0.05 from control. † Significantly different at p < 0.05 from KBrO₃-treated group. ǂ Significantly different at p < 0.05 from KBrO₃ and taurine+KBrO₃ treated group.</p

Effect of taurine pre-treatment on KBrO₃-induced changes in the kinetic parameters of BBM enzymes in purified BBMV.

<p>Effect of taurine pre-treatment on KBrO₃-induced changes in the kinetic parameters of BBM enzymes in purified BBMV.</p