Patients eligible but not on ART and patients followed up following a missed clinic appointment pre- and post-intervention.

<p>^* Two-sample test of proportions</p><p>^** patients eligible for ART, based on CD4 count ≤350 cells/μl or WHO clinical stage 3 or 4, but who have not yet started ART</p><p>^*** patients who have missed next appointment date by more than two weeks (as % of patients registered)</p><p>Patients eligible but not on ART and patients followed up following a missed clinic appointment pre- and post-intervention.</p

Demographic and clinical variables of active patients registered in the EMR system pre- and post-intervention.

<p>^* patients eligible for ART, based on CD4 or WHO stage, but who have not started ART</p><p>Demographic and clinical variables of active patients registered in the EMR system pre- and post-intervention.</p

Fluctuation in the prevalence of major sequence types (STs) associated with invasive isolates from Kilifi.

<p>Invasive isolates were collected from 1994-2008 and the major STs associated with serotypes 14 (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0081539#pone-0081539-g003" target="_blank">Figure 3A</a>) and 23F (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0081539#pone-0081539-g003" target="_blank">Figure 3B</a>) are depicted in each panel. The total number of isolates genotyped each year (see Methods) is stated in parentheses in the x-axis labels.</p