25 research outputs found

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Comparative study of fatty-acid composition of table eggs from the Jeddah food market and effect of value addition in omega-3 bio-fortified eggs

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    Health consciousness has increased the desire of people around the world to consume functional foods. Omega-3 essential fatty acids are one among these beneficial and important health supplements without which a general predisposition to degenerative and stress related disorders can occur. Saudi Arabia has shown an alarming increase in obesity (Al-Nozha et al., 2005), diabetes (Alqurashi et al., 2011), and cardiovascular disease (Al-Nozha et al., 2004) in the last few decades mainly due to nutritional transitions and lifestyle alterations (Amuna and Zotor, 2008). Lack of nutrient dense foods and the prevailing food related disorder of obesity (Popkin, 2001; Prentice, 2014) especially render egg as a choice food to be value-added for attaining nutritional security in Saudi Arabia and in effect reverse the increasing incidences of lifestyle diseases. Nutritional intervention through a commonly consumed food product would be an important step in improving the health of the people, and reducing health care costs. As eggs are a frequently consumed food item in Saudi Arabia, enriching them with omega-3 fatty acids would be an excellent way to alleviate the existing problems. A significant deposition of omega-3 fatty acids in the eggs was observed when the diet of hens was supplemented with omega-3 fatty acids from either flaxseed or fish oil source. Inadequacy of omega-3 fatty acids could thus be rectified by producing omega-3 enriched eggs from hens supplemented with flaxseed or fish oil source, and thus contribute toward better health choice of the consumer

    Correction to: Current therapies in alleviating liver disorders and cancers with a special focus on the potential of vitamin D

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    Abstract Following publication of the original article [1] one of the authors wrote to say that his name had been spelt incorrectly as Ahmed Makki instead of Ahmad Makki

    Panacea seed “Nigella”: A review focusing on regenerative effects for gastric ailments

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    Nigella sativa (NS) or black cumin is a dark, thin, and crescent-shaped, seeded shrub belonging to the Ranunculaceae family commonly growing on Mediterranean coasts in Saudi Arabia, northern Africa and Asia. They have amazing curative and therapeutic features that make them one of the most popular, safe, non-detrimental, and cytoprotective medicinal plant that can be used for prevention and treatment of many complicated diseases. Originally, N. sativa was used to treat migraines and allergy, and researches have shown its effectiveness in destroying cancer cells as well. The gastro protective effect of NS oil and its constituents has also been reported earlier; however, the complete perception on etiology and pathogenesis of gastric ulcer is not yet clear. Herein, we attempt to unveil some of the potential mechanisms exhibited by NS in preventing problems related to gastric ulcers. Gastric ailments like ulcers and tumors are the most common disorders of the gastro-intestinal tract in the present day life of the industrialized world. Gastric ulcer being a multifaceted problem exhibits complex etiology and is the fourth most common cause of cancer mortality. Drug interactions and toxicity are the main hindrances in chemotherapy. The existing merits and demerits of modern-day drugs make us turn toward the plant kingdom which may provide a valuable resource of novel potent natural compounds for pharmaceuticals or alternately, as dietary supplements. In this context, the revered phytotherapeutic N. sativa comes as a promising savior in today’s times. This review aims to summarize, both the functional and disease-related effects in the area of gastroenterology

    Synthesis of DMEA-Grafted Anion Exchange Membrane for Adsorptive Discharge of Methyl Orange from Wastewaters

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    This manuscript describes the synthesis of dimethylethanolamine (DMEA)-grafted anion exchange membrane (AEM) by incorporating dimethylethanolamine as ion-exchange content into the polymer matrix via the solution casting method. The synthesis of the DMEA-grafted AEM was demonstrated by Fourier transform infrared (FTIR) spectroscopy. The prepared DMEA-grafted AEM exhibited higher thermal stability, homogeneous morphology, water uptake (WR) of 115%, and an ion exchange capacity (IEC) of 2.70 meq/g. It was used for the adsorptive removal of methyl orange (MO) from an aqueous solution via batch processing. The effect of several operating factors, including contact time, membrane dosage, initial concentration of aqueous dye solution, and temperature on the percentage discharge of MO and adsorption capacity, was evaluated. Experimental data for adsorption of MO onto the DMEA-grafted AEM was analyzed with two parameter and three parameter nonlinear adsorption isotherm models but fitted best using a nonlinear Freundlich isotherm. Adsorption kinetics were studied by using several models, and attained results showed that experimental data fitted well to pseudo-second-order kinetics. A thermodynamic study showed that adsorption of MO onto the prepared DMEA-grafted AEM was an endothermic process. Moreover, it was a feasible and spontaneous process

    Synthesis of DMEA-Grafted Anion Exchange Membrane for Adsorptive Discharge of Methyl Orange from Wastewaters

    No full text
    This manuscript describes the synthesis of dimethylethanolamine (DMEA)-grafted anion exchange membrane (AEM) by incorporating dimethylethanolamine as ion-exchange content into the polymer matrix via the solution casting method. The synthesis of the DMEA-grafted AEM was demonstrated by Fourier transform infrared (FTIR) spectroscopy. The prepared DMEA-grafted AEM exhibited higher thermal stability, homogeneous morphology, water uptake (WR) of 115%, and an ion exchange capacity (IEC) of 2.70 meq/g. It was used for the adsorptive removal of methyl orange (MO) from an aqueous solution via batch processing. The effect of several operating factors, including contact time, membrane dosage, initial concentration of aqueous dye solution, and temperature on the percentage discharge of MO and adsorption capacity, was evaluated. Experimental data for adsorption of MO onto the DMEA-grafted AEM was analyzed with two parameter and three parameter nonlinear adsorption isotherm models but fitted best using a nonlinear Freundlich isotherm. Adsorption kinetics were studied by using several models, and attained results showed that experimental data fitted well to pseudo-second-order kinetics. A thermodynamic study showed that adsorption of MO onto the prepared DMEA-grafted AEM was an endothermic process. Moreover, it was a feasible and spontaneous process

    Adsorption kinetic, equilibrium and thermodynamic studies of eosin-B onto anion exchange membrane

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    In this research, batch adsorption of anionic dye Eosin-B (EB) onto anion exchange membrane (AEM) (BI) from aqueous solution has been investigated at room temperature. The effect of some operating conditions such as contact time, membrane dosage, initial dye concentration and temperature on the percentage removal of EB from aqueous solution has been investigated in detail. Moreover, adsorption kinetics has been analyzed using different models such as pseudo-first-order, pseudo-second-order, Elovich, liquid film diffusion, modified Freundlich and Bangham models. Results show that adsorption data fits to the pseudo-second order kinetics very well. Non-linear isotherms containing two parameters and three parameters isotherms have been applied on experimental data. Different thermodynamic parameters such as Gibb’s free energy (DG°), enthalpy (DH°), and entropy (DS°) have been calculated, which shows that adsorption of EB onto anion exchange membrane (B1) is an exothermic process.The authors are highly thankful to the CAS-TWAS President's fellowship for PhD financial support.Scopu

    Grazing and Cutting under Different Nitrogen Rates, Application Methods and Planting Density Strongly Influence Qualitative Traits and Yield of Canola Crop

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    Canola crop has the potential for both seeds and grazing. Optimal planting density, time of nitrogen (N) fertilizer application and rates are the major aspects for successful qualitative traits and canola yield formation. In this content, optimization of planting density, N levels and its time of application in dual purpose canola are needed. This study was carried out in RCB design with split pot arrangement having three repeats during winter 2012–2013 and 2013–2014. The study evaluated N levels (120 and 80 kg N ha−1), cutting treatment, N application timings and planting density (20 and 40 plants m−2) effects on qualitative traits and yield of canola. No-cut treatment had 7.02%, 2.46%, and 4.26% higher, glucosinolates, oil, and protein content with 31.3% and 30.5% higher biological and grain yield respectively, compared with grazed canola. Compared with no-cut canola, grazed canola resulted in 7.74% of higher erucic acid. Further, application of N at 120 kg N ha−1 had 8.81%, 5.52%, and 6.06% higher glucosinolates, percent protein, and seed yield, respectively than 80 kg N ha−1. In-addition, the application of N into two splits was most beneficial than the rest application timings. Cutting had 15% reduction in grain yield of canola and fetched additional income of 143.6 USD compared with no-cut. Grazing resulted in a 23% reduction in grain yield while had additional income of 117.7 USD from fodder yield. Conclusively, the application of N in two splits at 120 kg N ha−1 combined with 20 plants m−2 is a promising strategy to achieve good qualitative attributes and canola yield under dual purpose system

    A Novel four-way complex variant translocation involving chromosome 46, XY, t(4;9; 19;22)(q25:q34;p13.3;q11.2) in a chronic myeloid leukemia patient

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    Philadelphia (Ph) chromosome (9; 22)(q34;q11) is well established in more than 90% of chronic myeloid leukemia (CML) patients and the remaining 5-8% CML patients show variant and complex translocations, with the involvement of third, fourth or fifth chromosome other then 9;22. However, in very rare cases the fourth chromosome is involved. Here, we find a novel case of four way Ph+ chromosome translocation involving 46,XY, t(4;9;19;22)(q25:q34;p13.3;q11.2) with CML in the chronic phase. Complete blood cell count of CML patient was carried out to obtain total leukocytes count, hemoglobin and platelets. Fluorescence In situ hybridization technique was used for the identification of BCR-ABL fusion gene and cryptogenic test for the confirmation of Ph (9; 22)(q34;q11) and the mechanism of variant translocation in the bone marrow. The patient is successfully treated with Imatinib mesylate (Gleevec) with 400mg/day dose. We observed a significant decrease in WBC count after 48 months follow up 11.7 x109/L. Patient started feeling better generally. There was a reduction in the swelling of the body, fatigue and anxiety
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