Specialty Preference Among Medical Students and Factors Affecting It

Introduction: Medical education is one of the core part of educational system of any country. Medical education requires undergraduate students to study a wide range of medical specialties. It is often assumed that students do not make their career preferences until after they have graduated from medical school. So the reasons and factors responsible for preferences need to be found out among medical students. Material and Methods: It was a Cross sectional study on 180 medical students to assess preference for specialty and factors responsible. Results: Out of total 190 medical students more or less everyone (97.89%) wanted to pursue specialization and majority of them (96.84%) wanted to pursue the same in Medical Field(p>0.05). majority of male students were interested to pursue their specialization in the field of medicine (37.63%), surgery (23.65%) and pediatrics (13.97%). On the other hand female students were more interested in medicine (24.17%), pediatrics (32.96%) and obstetrics & gynecology (24.17%)(p<0.05). Interest, by far was found to be most common factor (76.63%) responsible for the preference of particular medical specialty among all four groups of students (1st professional-25.27%, 2nd professional-75.92%, final professional-89.47%, interns-68.42%).Conclusion: It is thus concluded there are many factors playing role in the specialty selection and preference among the medical students and should be equally justified and addressed

Biomaterials‐Based Approaches to Tumor Spheroid and Organoid Modeling

Evolving understanding of structural and biological complexity of tumors has stimulated development of physiologically relevant tumor models for cancer research and drug discovery. A major motivation for developing new tumor models is to recreate the 3D environment of tumors and context‐mediated functional regulation of cancer cells. Such models overcome many limitations of standard monolayer cancer cell cultures. Under defined culture conditions, cancer cells self‐assemble into 3D constructs known as spheroids. Additionally, cancer cells may recapitulate steps in embryonic development to self‐organize into 3D cultures known as organoids. Importantly, spheroids and organoids reproduce morphology and biologic properties of tumors, providing valuable new tools for research, drug discovery, and precision medicine in cancer. This Progress Report discusses uses of both natural and synthetic biomaterials to culture cancer cells as spheroids or organoids, specifically highlighting studies that demonstrate how these models recapitulate key properties of native tumors. The report concludes with the perspectives on the utility of these models and areas of need for future developments to more closely mimic pathologic events in tumors.State‐of‐the‐art approaches using natural, synthetic, and composite biomaterials for 3D tumor modeling are presented in this Progress Report. Furthermore, it is discussed how these models uniquely reproduce key properties of native tumors to facilitate basic and applied cancer research and cancer drug discovery efforts.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142941/1/adhm201700980.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142941/2/adhm201700980-sup-0001-S1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142941/3/adhm201700980_am.pd

ROLE OF EQUIPMENT MANAGEMENT IN OPTICAL TRANSPORT NETWORK

The ever-developing interest of present day society for information with enhanced execution over longer separations have made the system complex in terms of architecture, technologies, Network Elements, communication between Network Elements, security and signaling control. Equipment Management as a segment of Network Management System gives administrators the capacity to control general operation of the NEs, superintend interaction among NEs and to upper layer administration framework, thus automating the task of managing complex network. This paper presents the role of Equipment Management in Optical Transport Network and some of its challenges

Incidence of Snake Bites in Kashan, Iran During an Eight Year Period (2004-2011)

Background: Snake bites are one of the significant health problems in the tropical and subtropical regions. Snake bite is a common medical emergency in Iran, and the epidemiological features and management of such cases vary from region to region. Objectives: This present research study was conducted to obtain new information about the epidemiology of snake bites in the region of Kashan, located in the central part of Iran. Patients and Methods: This research was a descriptive retrospective study. Data from 2004 to 2011 of snakebite cases were collected from case reports. Information included; age and sex of the victim, district, month of incident, mortality, and time of bite. Results: The results of this study showed that the majority of snake bite patients were male (96%). The age distribution of patients indicated that the greatest rate of snake bites occurred among the 15-24 year old group. Data collected in this study revealed that the highest incidence of snake bite cases took place in summer (60%) and the lowest number occurred in winter, with no snake bite cases being recorded. The peak number of snakebite cases was seen during June-September. Conclusions: It was concluded that snake bite cases in Kashan are similar to other areas in Iran from an epidemiological point of view, including; age distribution rates, gender and site of the bites. The existence of Macrov ipera lebetina, a dangerous venomous snake, can cause a range of clinical effects among residents in central parts of Iran, such as Kashan area

Decoupling of a Neutron Interferometer from Temperature Gradients

Neutron interferometry enables precision measurements that are typically operated within elaborate, multi-layered facilities which provide substantial shielding from environmental noise. These facilities are necessary to maintain the coherence requirements in a perfect crystal neutron interferometer which is extremely sensitive to local environmental conditions such as temperature gradients across the interferometer, external vibrations, and acoustic waves. The ease of operation and breadth of applications of perfect crystal neutron interferometry would greatly benefit from a mode of operation which relaxes these stringent isolation requirements. Here, the INDEX Collaboration and National Institute of Standards and Technology demonstrates the functionality of a neutron interferometer in vacuum and characterize the use of a compact vacuum chamber enclosure as a means to isolate the interferometer from spatial temperature gradients and time-dependent temperature fluctuations. The vacuum chamber is found to have no depreciable effect on the performance of the interferometer (contrast) while improving system stability, thereby showing that it is feasible to replace large temperature isolation and control systems with a compact vacuum enclosure for perfect crystal neutron interferometry

Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events

Ytterbium triflate (and trimethylsilyl triflate) catalyzed isomerization of glycidic esters to α-hydroxy-β,γ-unsaturated esters and their conversion into cyclopentanoids using Johnson-Claisen rearrangement

A variety of glycidic esters undergo smooth isomerization to the corresponding &#945;-hydroxy-&#946;, &#947;-unsaturated esters upon reaction with Yb(OTf)3 or TMSOTf. These &#945;-hydroxy-&#946;, &#947;-unsaturated esters undergo Johnson-Claisen rearrangement to appropriately substituted diesters, some of which are converted into cyclopentanoids

Long-term impacts of integrated nutrient management with equivalent nutrient doses to mineral fertilization on soil organic carbon sequestration in a sub-tropical Alfisol of India

Limited evidence is available on carbon sequestration potential of long-term integrated nutrient management (INM) versus mineral fertilization, when equivalent amounts of nutrients were added. Hence, this study was carried out to understand the impact of 60 years of INM with adjusted nutrient doses and mineral fertilization in an Alfisol in a maize (Zea maysL.)-wheat (Triticum aestivumL.) system on soil organic carbon (SOC) sequestration in surface (0-30 cm) and deep (30-60 cm) soil layers. Conventional tillage was done twice before sowing of both maize and wheat using a spade. In farmyard manure (FYM) and lime treated plots (FYMP'K'L: plots with nitrogen (N) applied in terms of FYM; additional dose of phosphorus (P) and potassium (K) and lime) total SOC concentration was nearly 83% higher than unfertilized control plots. The FYMP'K'L plots had similar to 11% more total SOC concentration than plots treated with mineral fertilizer and lime (NPKL: recommended dose of N, P, K and lime) in the 0-30 cm soil layer. Labile C, including KMnO4-C, was more in plots with FYM than NPKL plots, whereas the recalcitrant C stock was more in NPKL than FYM treated plots. In the 0-60 cm soil layer, the labile C stock was highest in FYMP'K'L plots, but the recalcitrant C stock was highest in NPKL. Total SOC accumulation rate (over unfertilized control plots) was highest for FYMP'K'L plots (0.38 Mg ha(-1 )year(-1)) in the surface soil layer, whereas SOC sequestration rate was highest in NPKL plots (0.18 Mg ha(-1 )year(-1)) in the deep layer and in the 0-60 cm layer. Overall, although NPKL management practice had the highest C sequestration in the 0-60 cm layer, FYMP'K'L had the best CMI and labile C pools. Thus, resource poor farmers need not to use full doses of NPK and FYM for soil C management in the region