27 research outputs found
The Artificial Intelligence Journal Club (#RADAIJC): A Multi-Institutional Resident-Driven Web-Based Educational Initiative
No full textA Deep-Learning System for Fully-Automated Peripherally Inserted Central Catheter (PICC) Tip Detection
No full text
Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model
No full textFigure S6 from Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
No full textVaried levels of PI3Kα-dependency across cell lines</p
Supplemental Text from Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
No full textSynthesis of mutant-selective allosteric PI3Kα inhibitors</p
Figure S3 from Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
No full textBinding kinetics and potency of [2] towards PI3Kα</p
Supplemental Text from Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
No full textSynthesis of mutant-selective allosteric PI3Kα inhibitors</p
Figure S1 from Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
No full textActivation loop residues 937-954 are more disordered in mutant vs. wildtype PI3Kα</p
