12,663 research outputs found
An Experiment and Detection Scheme for Cavity-based Cold Dark Matter Searches
A resonance detection scheme and some useful ideas for cavity-based searches
of light cold dark matter particles (such as axions) are presented, as an
effort to aid in the on-going endeavors in this direction as well as for future
experiments, especially in possibly developing a table-top experiment. The
scheme is based on our idea of a resonant detector, incorporating an integrated
Tunnel Diode (TD) and a GaAs HEMT/HFET (High Electron Mobility
Transistor/Heterogenous FET) transistor amplifier, weakly coupled to a cavity
in a strong transverse magnetic field. The TD-amplifier combination is
suggested as a sensitive and simple technique to facilitate resonance detection
within the cavity while maintaining excellent noise performance, whereas our
proposed Halbach magnet array could serve as a low-noise and permanent solution
replacing the conventional electromagnets scheme. We present some preliminary
test results which demonstrate resonance detection from simulated test signals
in a small optimal axion mass range with superior Signal-to-Noise Ratios (SNR).
Our suggested design also contains an overview of a simpler on-resonance dc
signal read-out scheme replacing the complicated heterodyne readout. We believe
that all these factors and our propositions could possibly improve or at least
simplify the resonance detection and read-out in cavity-based DM particle
detection searches (and other spectroscopy applications) and reduce the
complications (and associated costs), in addition to reducing the
electromagnetic interference and background.Comment: 22 pages, 7 figure
MATLAB Simulink model of a photovoltaic cell
Материалы XVIII Междунар. науч.-техн. конф. студентов, аспирантов и молодых ученых, Гомель, 26–27 апр. 2018 г
Comparative Proteomic Profiling of Methicillin‐Susceptible and Resistant Staphylococcus aureus
Purpose
Staphylococcus aureus is a highly successful human pathogen responsible for wide range of infections. In this study, we provide insights into the virulence, pathogenicity, and antimicrobial resistance determinants of methicillin susceptible and methicillin resistant Staphylococcus aureus (MSSA; MRSA) recovered from non‐healthcare environments.
Experiment design
Three environmental MSSA and three environmental MRSA were selected for proteomic profiling using iTRAQ MS/MS. Gene Ontology (GO) Annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathway Annotation were applied to interpret the functions of the proteins detected.
Results
792 proteins were identified in MSSA and MRSA. Comparative analysis of MRSA and MSSA revealed that 8 of out 792 proteins were up‐regulated and 156 were down‐regulated. Proteins that had differences in abundance were predominantly involved in catalytic and binding activity. Among 164 differently abundant proteins, 29 were involved in pathogenesis, antimicrobial resistance, stress response, mismatch repair and cell wall synthesis. Twenty‐two proteins associated with pathogenicity, including spa, sbi, clfA and dlt were up‐regulated in MRSA. Moreover, the up‐regulated pathogenic protein entC2 in MSSA was determined to be a super antigen potentially capable of triggering toxic shock syndrome in the host.
Conclusions
Enhanced pathogenicity, antimicrobial resistance and stress response were observed in MRSA compared to MSSA
Disaster management using D2D communication with power transfer and clustering techniques
Device-to-device (D2D) communications as an underlay to cellular networks can not only increase the system capacity and energy efficiency but also enable national security and public safety services. A key requirement for these services is to provide alternative access to cellular networks when they are partially or fully damaged due to a natural disaster event. In this paper, we employ energy harvesting (EH) at the relay with simultaneous wireless information and power transfer to prolong the lifetime of energy constrained network. In particular, we consider a user equipment relay that harvests energy from radio frequency signal via base station and use harvested energy for D2D communications. We integrate clustering technique with D2D communications into cellular networks such that communication services can be maintained when the cellular infrastructure becomes partially dysfunctional. Simulation results show that our proposed EH-based D2D clustering model performs efficiently in terms of coverage, energy efficiency, and cluster formation to extend the communication area. Moreover, a novel concept of power transfer in D2D clustering with user equipment relay and cluster head is proposed to provide a new framework to handle critical and emergency situations. The proposed approach is shown to provide significant energy saving for both mobile users and clustering heads to survive in emergency and disaster situations
Challenges in compression testing of 3D angle-interlocked woven-glass fabric-reinforced polymeric composites.
This paper describes the challenges in using testing standards such as D6641/D6641M-14, for determination of compressive strength of 3D angle interlocked glass fabric reinforced polymeric composites (3D-FRPC). It makes use of both experimental investigation and finite element analysis. The experimental investigation involved testing both 2D and 3D-FRPC using ASTM D6641/D6641M-14 and subsequent scanning electron microscopic imaging of failed specimens to reveal the stress state at failure. This was further evaluated using laminate level finite element (FE) analysis. The FE analysis required input of effective orthotropic elastic material properties of 3D-FRPC, which were determined by customizing a recently developed micro-mechanical model. The paper sheds new light on compressive failure of 3D angle interlocked glass fabric composites, as only scarce data is available in literature about this class of materials. It showed that although the tests produce acceptable strength values the internal failure mechanisms change significantly and the standard deviation (SD) and coefficient of variance (COV) of 3D-FRPC comes out to be much higher than that of 2D-FRPC. Moreover, while reporting and using the test data some additional information about the 3D-fabric architecture, such as the direction of angle interlocking fabric needs to be specified. This was because, for 3D angle interlocking of fabric along warp direction, the strength values obtained in the warp and weft direction were significantly different from each other. The study also highlights that due to complex weave architecture it is not possible to achieve comparable volume fractions with 2D and 3D fabric reinforced composites using similar manufacturing parameters for the vacuum assisted resin infusion process. Thus, the normalized compressive strength values (normalized with respect to volume fraction) are the highest for 3D-FRPC when measured along the warp direction, they are at an intermediate level for 2D-FRPC and the lowest for 3D-FRPC, when measured in the weft direction.DelPHE 780 Project grant (DFID UK
MALDI TOF MS and currently related proteomic technologies in reconciling bacterial systematics
The chapter is on development and application of matrix assisted laser desorption ionisation time of flight mass spectrometry (MALDI-TOF) to identification and and classification of bacteria
Fulminant hepatic failure in pregnant women: acute fatty liver or acute viral hepatitis?
Background: Hepatitis E virus, which is endemic in our region, can cause severe liver dysfunction in pregnant women and this can be clinically confused with acute fatty liver of pregnancy.
Methods: We studied the clinical and laboratory data as well as the maternal and fetal outcomes of 12 pregnant women presenting with fulminant hepatic failure in order to determine the etiology of the disease. The clinical diagnoses were subsequently correlated with serologic assays for acute HEV infection. All patients were severely ill with deep jaundice, grade 3-4 encephalopathy and abnormal prothrombin times.
Results: A clinical diagnosis of acute viral hepatitis was made in nine patients and of acute fatty liver in the other three cases. IgM and IgG antibodies confirmed acute viral hepatitis E in six of the nine patients while one had acute hepatitis A infection. HEV IgM and IgG antibodies were, however, also positive in two of the three patients thought to have acute fatty liver. Maternal and fetal mortality were 16.6% and 50%, respectively.CONCLUSIONS: We conclude that hepatitis E is the usual cause of acute liver failure in our pregnant women and that clinical and laboratory features do not permit accurate distinction between acute HEV infection and acute fatty liver of pregnancy. The prognosis in patients with acute HEV infection is much better than in other groups with severe liver failure (mortality 16% vs 68%)
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