147 research outputs found
Convergence of the Linear Delta Expansion in the Critical O(N) Field Theory
The linear delta expansion is applied to the 3-dimensional O(N) scalar field
theory at its critical point in a way that is compatible with the large-N
limit. For a range of the arbitrary mass parameter, the linear delta expansion
for converges, with errors decreasing like a power of the order n in
delta. If the principal of minimal sensitivity is used to optimize the
convergence rate, the errors seem to decrease exponentially with n.Comment: 26 pages, latex, 8 figure
GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology
Friedreich ataxia (FRDA) is a neurodegenerative disorder caused by an unstable GAA repeat expansion mutation within intron 1 of the FXN gene. However, the origins of the GAA repeat expansion, its unstable dynamics within different cells and tissues, and its effects on frataxin expression are not yet completely understood. Therefore, we have chosen to generate representative FRDA mouse models by using the human FXN GAA repeat expansion itself as the genetically modified mutation. We have previously reported the establishment of two lines of human FXN YAC transgenic mice that contain unstable GAA repeat expansions within the appropriate genomic context. We now describe the generation of FRDA mouse models by crossbreeding of both lines of human FXN YAC transgenic mice with heterozygous Fxn knockout mice. The resultant FRDA mice that express only human-derived frataxin show comparatively reduced levels of frataxin mRNA and protein expression, decreased aconitase activity, and oxidative stress, leading to progressive neurodegenerative and cardiac pathological phenotypes. Coordination deficits are present, as measured by accelerating rotarod analysis, together with a progressive decrease in locomotor activity and increase in weight. Large vacuoles are detected within neurons of the dorsal root ganglia (DRG), predominantly within the lumbar regions in 6-month-old mice, but spreading to the cervical regions after 1 year of age. Secondary demyelination of large axons is also detected within the lumbar roots of older mice. Lipofuscin deposition is increased in both DRG neurons and cardiomyocytes, and iron deposition is detected in cardiomyocytes after 1 year of age. These mice represent the first GAA repeat expansion-based FRDA mouse models that exhibit progressive FRDA-like pathology and thus will be of use in testing potential therapeutic strategies, particularly GAA repeat-based strategies. © 2006 Elsevier Inc. All rights reserved
Critical thermodynamics of three-dimensional MN-component field model with cubic anisotropy from higher-loop \epsilon expansion
The critical thermodynamics of an -component field model with cubic
anisotropy relevant to the phase transitions in certain crystals with
complicated ordering is studied within the four-loop \ve expansion using the
minimal subtraction scheme. Investigation of the global structure of RG flows
for the physically significant cases M=2, N=2 and M=2, N=3 shows that the model
has an anisotropic stable fixed point with new critical exponents. The critical
dimensionality of the order parameter is proved to be equal to
, that is exactly half its counterpart in the real hypercubic
model.Comment: 9 pages, LaTeX, no figures. Published versio
Higher Order Evaluation of the Critical Temperature for Interacting Homogeneous Dilute Bose Gases
We use the nonperturbative linear \delta expansion method to evaluate
analytically the coefficients c_1 and c_2^{\prime \prime} which appear in the
expansion for the transition temperature for a dilute, homogeneous, three
dimensional Bose gas given by T_c= T_0 \{1 + c_1 a n^{1/3} + [ c_2^{\prime}
\ln(a n^{1/3}) +c_2^{\prime \prime} ] a^2 n^{2/3} + {\cal O} (a^3 n)\}, where
T_0 is the result for an ideal gas, a is the s-wave scattering length and n is
the number density. In a previous work the same method has been used to
evaluate c_1 to order-\delta^2 with the result c_1= 3.06. Here, we push the
calculation to the next two orders obtaining c_1=2.45 at order-\delta^3 and
c_1=1.48 at order-\delta^4. Analysing the topology of the graphs involved we
discuss how our results relate to other nonperturbative analytical methods such
as the self-consistent resummation and the 1/N approximations. At the same
orders we obtain c_2^{\prime\prime}=101.4, c_2^{\prime \prime}=98.2 and
c_2^{\prime \prime}=82.9. Our analytical results seem to support the recent
Monte Carlo estimates c_1=1.32 \pm 0.02 and c_2^{\prime \prime}= 75.7 \pm 0.4.Comment: 29 pages, 3 eps figures. Minor changes, one reference added. Version
in press Physical Review A (2002
Convergent resummed linear delta expansion in the critical O(N) (\phi_i^2)^2_{3d} model
The nonperturbative linear delta expansion (LDE) method is applied to the
critical O(N) phi^4 three-dimensional field theory which has been widely used
to study the critical temperature of condensation of dilute weakly interacting
homogeneous Bose gases. We study the higher order convergence of the LDE as it
is usually applied to this problem. We show how to improve both, the large-N
and finite N=2, LDE results with an efficient resummation technique which
accelerates convergence. In the large N limit, it reproduces the known exact
result within numerical integration accuracy. In the finite N=2 case, our
improved results support the recent numerical Monte Carlo estimates for the
critical transition temperature of Bose-Einstein condensation.Comment: 4 pages, Revtex 4. A misprint in Eq. (3) was corrected and ref. 17
(cond-mat/0207295) update
On the Divergence of Perturbation Theory. Steps Towards a Convergent Series
The mechanism underlying the divergence of perturbation theory is exposed.
This is done through a detailed study of the violation of the hypothesis of the
Dominated Convergence Theorem of Lebesgue using familiar techniques of Quantum
Field Theory. That theorem governs the validity (or lack of it) of the formal
manipulations done to generate the perturbative series in the functional
integral formalism. The aspects of the perturbative series that need to be
modified to obtain a convergent series are presented. Useful tools for a
practical implementation of these modifications are developed. Some resummation
methods are analyzed in the light of the above mentioned mechanism.Comment: 42 pages, Latex, 4 figure
Dependence of Variational Perturbation Expansions on Strong-Coupling Behavior. Inapplicability of delta-Expansion to Field Theory
We show that in applications of variational theory to quantum field theory it
is essential to account for the correct Wegner exponent omega governing the
approach to the strong-coupling, or scaling limit. Otherwise the procedure
either does not converge at all or to the wrong limit. This invalidates all
papers applying the so-called delta-expansion to quantum field theory.Comment: Author Information under
http://www.physik.fu-berlin.de/~kleinert/institution.html . Latest update of
paper (including all PS fonts) at
http://www.physik.fu-berlin.de/~kleinert/34
Renormalons and Analytic Properties of the \beta function
The presence or absense of renormalon singularities in the Borel plane is
shown to be determined by the analytic properties of the Gell-Mann - Low
function \beta(g) and some other functions. A constructive criterion for the
absense of singularities consists in the proper behavior of the \beta function
and its Borel image B(z) at infinity, \beta(g)\sim g^\alpha and B(z)\sim
z^\alpha with \alpha\le 1. This criterion is probably fulfilled for the \phi^4
theory, QED and QCD, but is violated in the O(n)-symmetric sigma model with
n\to\infty.Comment: 6 pages, PD
Solvable simulation of a double-well problem in PT symmetric quantum mechanics
Within quantum mechanics which works with parity-pseudo-Hermitian
Hamiltonians we study the tunneling in a symmetric double well formed by two
delta functions with complex conjugate strengths. The model is exactly solvable
and exhibits several interesting features. Besides an amazingly robust absence
of any PT symmetry breaking, we observe a quasi-degeneracy of the levels which
occurs all over the energy range including the high-energy domain. This pattern
is interpreted as a manifestation of certain "quantum beats".Comment: 12 pages incl. 7 figure
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