2 research outputs found
Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI
Polycystic ovary syndrome (PCOS) is an endocrine disorder in
women. Omentin-1 and vaspin are secretary adipokines that are
produced by the visceral adipose tissue. These levels change in
obese women with PCOS. The aim of this study is to investigate
whether omentin and vaspin levels change in nonobese PCOS
subjects. This study is a cross-sectional case control study in
which 39 women with PCOS were picked out for this study. The
inclusion criteria were based on the Rotterdam 2003 diagnostic
criteria. The control group consisted of 39 women with normal
pelvic sonographic reports having regular menstruation and
showing no signs of infertility. The fasting plasma glucose
(FPG), triglyceride (TG), Chol, and high-density lipoprotein
cholesterol (HDL-C), insulin, testosterone, omentin and vaspin
were measured by the enzymatic methods. The differences
within these groups were calculated by the un-paired t-test
and the Mann–Whitney test. The results from this study show
a significant increase in the amount of insulin, testosterone,
homeostasis model assessments for insulin resistance, TG and
lower HDL in the patient group. No significant differences were
seen in omentin, vaspin, FPG, Cho, low-density lipoprotein, very
low-density lipoprotein cholesterol, blood urea nitrogen, Cr
and homeostasis model assessments for B cell function levels
between groups. Results show that PCOS is not a determinant
of decreased omentin and vaspin plasma levels and those high
androgen level and insulin resistances are warning signs of
PCOS
Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI
Polycystic ovary syndrome (PCOS) is an endocrine disorder in women. Omentin-1 and vaspin are secretary adipokines that are produced by the visceral adipose tissue. These levels change in obese women with PCOS. The aim of this study is to investigate whether omentin and vaspin levels change in nonobese PCOS subjects. This study is a cross-sectional case control study in which 39 women with PCOS were picked out for this study