Gauged W Algebras

We perform an Hamiltonian reduction on a classical \cw(\cg, \ch) algebra, and prove that we get another \cw(\cg, \ch$'$) algebra, with $\ch\subset\ch'$. In the case \cg=S\ell(n), the existence of a suitable gauge, called Generalized Horizontal Gauge, allows to relate in this way two \cw-algebras as soon as their corresponding \ch-algebras are related by inclusion.Comment: 11 p., Latex. There was a misprint on the last autho

Derivative corrections to the Born-Infeld action through beta-function calculations in N=2 boundary superspace

We calculate the beta-functions for an open string sigma-model in the presence of a U(1) background. Passing to N=2 boundary superspace, in which the background is fully characterized by a scalar potential, significantly facilitates the calculation. Performing the calculation through three loops yields the equations of motion up to five derivatives on the fieldstrengths, which upon integration gives the bosonic sector of the effective action for a single D-brane in trivial bulk background fields through four derivatives and to all orders in alpha'. Finally, the present calculation shows that demanding ultra-violet finiteness of the non-linear sigma-model can be reformulated as the requirement that the background is a deformed stable holomorphic U(1) bundle.Comment: 25 pages, numerous figure

Strings from N=2N=2 Gauged Wess-Zumino-Witten Models

We present an algebraic approach to string theory. An embedding of $sl(2|1)$ in a super Lie algebra together with a grading on the Lie algebra determines a nilpotent subalgebra of the super Lie algebra. Chirally gauging this subalgebra in the corresponding Wess-Zumino-Witten model, breaks the affine symmetry of the Wess-Zumino-Witten model to some extension of the $N=2$ superconformal algebra. The extension is completely determined by the $sl(2|1)$ embedding. The realization of the superconformal algebra is determined by the grading. For a particular choice of grading, one obtains in this way, after twisting, the BRST structure of a string theory. We classify all embeddings of $sl(2|1)$ into Lie super algebras and give a detailed account of the branching of the adjoint representation. This provides an exhaustive classification and characterization of both all extended $N=2$ superconformal algebras and all string theories which can be obtained in this way.Comment: 50 pages, LaTe

On the Lagrangian Realization of Non-Critical W{\cal W}-Strings

A large class of non-critical string theories with extended worldsheet gauge symmetry are described by two coupled, gauged Wess-Zumino-Witten Models. We give a detailed analysis of the gauge invariant action and in particular the gauge fixing procedure and the resulting BRST symmetries. The results are applied to the example of ${\cal W}_3$ strings.Comment: 19 pages, LaTeX (REVTEX macro's

Supersymmetric non-linear sigma-models with boundaries revisited

We study two-dimensional supersymmetric non-linear sigma-models with boundaries. We derive the most general family of boundary conditions in the non-supersymmetric case. Next we show that no further conditions arise when passing to the N=1 model. We present a manifest N=1 off-shell formulation. The analysis is greatly simplified compared to previous studies and there is no need to introduce non-local superspaces nor to go (partially) on-shell. Whether or not torsion is present does not modify the discussion. Subsequently, we determine under which conditions a second supersymmetry exists. As for the case without boundaries, two covariantly constant complex structures are needed. However, because of the presence of the boundary, one gets expressed in terms of the other one and the remainder of the geometric data. Finally we recast some of our results in N=2 superspace and discuss applications.Comment: LaTeX, 23 page

The Semi-Chiral Quotient, Hyperkahler Manifolds and T-duality

We study the construction of generalized Kahler manifolds, described purely in terms of N=(2,2) semichiral superfields, by a quotient using the semichiral vector multiplet. Despite the presence of a b-field in these models, we show that the quotient of a hyperkahler manifold is hyperkahler, as in the usual hyperkahler quotient. Thus, quotient manifolds with torsion cannot be constructed by this method. Nonetheless, this method does give a new description of hyperkahler manifolds in terms of two-dimensional N=(2,2) gauged non-linear sigma models involving semichiral superfields and the semichiral vector multiplet. We give two examples: Eguchi-Hanson and Taub-NUT. By T-duality, this gives new gauged linear sigma models describing the T-dual of Eguchi-Hanson and NS5-branes. We also clarify some aspects of T-duality relating these models to N=(4,4) models for chiral/twisted-chiral fields and comment briefly on more general quotients that can give rise to torsion and give an example.Comment: 31 page

A Hierarchy of Superstrings

We construct a hierarchy of supersymmetric string theories by showing that the general N-extended superstrings may be viewed as a special class of the (N+1)-extended superstrings. As a side result, we find a twisted (N+2) superconformal algebra realized in the N-extended string.Comment: 9 pages, LaTex, NBI-HE-94-2

A Photocleavable Contrast Agent for Light-Responsive MRI

Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents' relaxivity with the aim to increase the sensitivity, selectivity and amount of functional information obtained from this outstanding whole-body medical imaging technique. This approach requires the development of molecular contrast agents that show high relaxivity and strongly pronounced photo-responsiveness. To this end, we report here the design and synthesis of a light-activated MRI contrast agent, together with its evaluation using UV-vis spectroscopy, Fast Field Cycling (FFC) relaxometry and relaxometric measurements on clinical MRI scanners. The high relaxivity of the reported agent changes substantially upon irradiation with light, showing a 17% decrease in relaxivity at 0.23T upon irradiation with lambda = 400 nm (violet) light for 60 min. On clinical MRI scanners (1.5T and 3.0T), irradiation leads to a decrease in relaxivity of 9% and 19% after 3 and 60 min, respectively. The molecular design presents an important blueprint for the development of light-activatable MRI contrast agents