Stabilization and Balance Exercise Benefits in Amyotrophic Lateral Sclerosis: A Case Report

Background: ALS is the most devastating form of motor neuron disease, and the chance of survival is 3 to 5 years after the diagnosis is made. The pathogenesis of the disease is unknown. Several upper and lower motor neuron symptoms such as weakness, gait bradykinesia, and muscle atrophy have been reported. The core muscles are considered to be the center of the functional kinetic chain due to the links with upper and lower limbs. Methods: The patient in this case study was a 42 year-old woman suffering from ALSfor two years prior to the study. She had typical upper and lower motor symptoms, but her chief complaints were inability to walk, standing balance impairment, and a tendency to fall posteriorly. She performed core stabilization exercises, which were done three times per day. She was followed for three months. Results: Core stabilization exercises improved her quality of life, and she could walk independently after three months of exercise. In addition, her tendency toward falling posteriorly was completely alleviated. Conclusion: Core stabilization exercises were beneficial to the patient, and she was satisfied because her quality of life had improved

Evaluation of Wound Dressing Made From Spider Silk Protein Using in a Rabbit Model

The aim of the present article was to study the healing of wounds using spider silk. Eight New Zealand female rabbits were selected as animal model. First, 3 identical wounds with length of 15 mm and a depth of 4 mm on the back of each rabbit were created. The first group, as standard control, did not receive any special treatment, they were treated only with saline and Vaseline locally. The second group, as positive control, received a thin film of phenytoin 1% ointment locally. The third group, as treated group, received a thin film of spider silk protein. At the end of the study, a biopsy of skin was done. After tissue preparation, all sections were evaluated. Some morphometrical parameters such as counting cells, fibroblasts, blood vessels, determination of the area of the wound closure, necrotic tissue, speed of wound healing, and epidermal thickness were done, and for data statistical analysis, SPSS software and Excel software were used. The results of this study showed that spider silk dressing may benefit as a possible effect of nanoparticles in the test preparation in wound healin