Identification of Deterioration caused by AHF, MADS or CE by RR and QT Data Classification

A sharp deterioration of the patient’s condition against the backdrop of the development of life-threatening arrhythmias with symptoms of acute heart failure (AHF), multiple organ dysfunction syndrome (MODS) or cerebral edema (CE) can lead to the death of the patient. Since the known methods of automated diagnostics currently cannot accurately and promptly determine that the patient is in a life-threatening condition leading to the fatal outcome caused by AHF, MODS or CE, there is a need to develop appropriate methods. One of the ways to identify predictors of such a state is to apply machine learning methods to the collected datasets. In this article, we consider using data analysis methods to test the hypothesis that there is a predictor of death risk assessment, which can be derived from the previously obtained values of the ECG intervals, which gives a statistically significant difference for the ECG of the two groups of patients: those who suffered deterioration leading to the fatal outcome caused be MODS, AHF or CE, and those with favorable outcome. A method for unifying ECG data was proposed, which allow, based on the sequence of RR and QT intervals, to the construct of a number that is a characteristic of the patient's heart condition. Based on this characteristic, the patients are classified into groups: the main (patients with fatal outcome) and control (patients with favorable outcome). The resulting classification method lays the potential for the development of methods for identifying the patient's health condition, which will automate the detection of its deterioration. The novelty of the result lies in the confirmation of the hypothesis stated above, as well as the proposed classification criteria that allow solving the urgent problem of an automatic detection of the deterioration of the patient's condition

Cytogenetic Effects in Patients after Computed Tomography Examination

Millions of people around the world are exposed to low doses of ionizing radiation from diagnostic computed tomography (CT) scans. Currently available data on the potential cancer risk after CT scans are contradictory and therefore demand further investigations. The aim of the current study was to obtain estimations of genome damage after CT scans in 42 non-cancer patients and to conduct a comparison of the results with 22 control subjects. The frequency of dicentric ring chromosomes and chromosome breaks was significantly increased in irradiated patients compared to the controls. The distribution of dicentrics among the cells demonstrated non-Poisson distribution that reflected non-uniform and partial-body radiation exposure. A fraction of patients followed Poisson distribution, which is typical for uniform whole-body exposures. Some patients demonstrated a level of dicentrics similar to the control subjects. The individual variations in the frequency and dicentric distribution suggested complex mechanisms of chromosome aberration induction and elimination that could be associated with individual radiosensitivity, as well as previous diagnostics that used ionizing radiation or the redistribution of small fractions of irradiated lymphocytes within the circulatory pull. In conclusion, CT scans may cause genome damage and possible increases in cancer risk. The introduction of a specific follow-up of such patients, especially in the case of repeated CT scans, is suggested

MODELING OF MANUFACTURING ERRORS FOR PIN-GEAR ELEMENTS OF PLANETARY GEARBOX

Theoretical background for calculation of k-h-v type cycloid reducers was developed relatively long ago. However, recently the matters of cycloid reducer design again attracted heightened attention. The reason for that is that such devices are used in many complex engineering systems, particularly, in mechatronic and robotics systems. The development of advanced technological capabilities for manufacturing of such reducers today gives the possibility for implementation of essential features of such devices: high efficiency, high gear ratio, kinematic accuracy and smooth motion. The presence of an adequate mathematical model gives the possibility for adjusting kinematic accuracy of the reducer by rational selection of manufacturing tolerances for its parts. This makes it possible to automate the design process for cycloid reducers with account of various factors including technological ones. A mathematical model and mathematical technique have been developed giving the possibility for modeling the kinematic error of the reducer with account of multiple factors, including manufacturing errors. The errors are considered in the way convenient for prediction of kinematic accuracy early at the manufacturing stage according to the results of reducer parts measurement on coordinate measuring machines. During the modeling, the wheel manufacturing errors are determined by the eccentricity and radius deviation of the pin tooth centers circle, and the deviation between the pin tooth axes positions and the centers circle. The satellite manufacturing errors are determined by the satellite eccentricity deviation and the satellite rim eccentricity. Due to the collinearity, the pin tooth and pin tooth hole diameter errors and the satellite tooth profile errors for a designated contact point are integrated into one deviation. Software implementation of the model makes it possible to estimate the pointed errors influence on satellite rotation angle error and reasonable selection of accuracy parameters for technological processes related to reducer parts manufacture. Additionally, it gives the possibility for estimation of the reducer kinematic error according to measurements by means of a coordinate measuring machine and diagnostics of reducer parts manufacturing errors by means of its kinematogram analysis. The model is implemented as a program developed in Microsoft Visual C++ 6.0 environment. Obtained results have found their application in CAD of cycloid reducers

Actuator technology and market outlook: where does the actuator move

The purpose of the article is an objective review of the global actuator market, as well as identifying the key factors of demand shifting from traditional hydraulic and pneumatic drives towards more innovative electromechanical actuators. In the article the basic market characteristics such as the volume and dynamics of the market, the market structure of consumption by segments, the key factors of the decision making, the economic feasibility of electromechanical actuators installation are reviewed. The main method used in this article writing is a review of existing Russian and foreign studies in the field of actuator economy and technology. The authors performed market analysis and compared the basic technical characteristics of existing actuators. There are made conclusions about the "migration" of demand from hydraulic and pneumatic solutions to electromechanical actuators in the aerospace and manufacturing industries. Identify advantages of electromechanics over more traditional actuators in terms of energy efficiency and reliability. Also identify the most promising areas of the drive technological development