2,541 research outputs found

    Percolation properties of growing networks under an Achlioptas process

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    We study the percolation transition in growing networks under an Achlioptas process (AP). At each time step, a node is added in the network and, with the probability δ\delta, a link is formed between two nodes chosen by an AP. We find that there occurs the percolation transition with varying δ\delta and the critical point δc=0.5149(1)\delta_c=0.5149(1) is determined from the power-law behavior of order parameter and the crossing of the fourth-order cumulant at the critical point, also confirmed by the movement of the peak positions of the second largest cluster size to the δc\delta_c. Using the finite-size scaling analysis, we get β/νˉ=0.20(1)\beta/\bar{\nu}=0.20(1) and 1/νˉ=0.40(1)1/\bar{\nu}=0.40(1), which implies β1/2\beta \approx 1/2 and νˉ5/2\bar{\nu} \approx 5/2. The Fisher exponent τ=2.24(1)\tau = 2.24(1) for the cluster size distribution is obtained and shown to satisfy the hyperscaling relation.Comment: 4 pages, 5 figures, 1 table, journal submitte

    Effect of pitavastatin on erythrocyte membrane fatty acid content in patients with chronic kidney disease: two-arm parallel randomized controlled trial.

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    BACKGROUND: Statins reduce the risk of cardiovascular events in patients with chronic kidney disease (CKD). Although diabetes mellitus (DM) is a reported side effect of statin treatment, some studies have indicated that pitavastatin does not cause DM. The present study investigated the effect of pitavastatin on the fatty acid (FA) content of erythrocyte membranes, which affects the occurrence of DM and cardiovascular diseases. In addition, changes in adiponectin and glycated hemoglobin (HbA1c) levels were evaluated after pitavastatin treatment. METHODS: A total of 45 patients were enrolled, 28 of whom completed the study. Over 24 weeks, 16 patients received 2 mg pitavastatin and 12 patients received 10 mg atorvastatin. Dosages were adjusted after 12 weeks if additional lipid control was required. There were 10 and nine patients with DM in the pitavastatin and atorvastatin groups, respectively. Erythrocyte membrane FAs and adiponectin levels were measured using gas chromatography and enzyme-linked immunosorbent assay, respectively. RESULTS: In both groups, saturated FAs, palmitic acid, trans-oleic acid, total cholesterol, and low-density lipoprotein cholesterol levels were significantly lower than those at baseline. The arachidonic acid (AA) content in the erythrocyte membrane increased significantly in the pitavastatin group, but adiponectin levels were unaffected. HbA1c levels decreased in patients treated with pitavastatin. No adverse effects were associated with statin treatment. CONCLUSION: Pitavastatin treatment in patients with CKD may improve glucose metabolism by altering erythrocyte membrane AA levels. In addition, pitavastatin did not adversely affect glucose control in patients with CKD and DM

    Intensification of terrestrial carbon cycle related to El Nino-Southern Oscillation under greenhouse warming

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    The El Nino/Southern Oscillation (ENSO) drives interannual variation in the global carbon cycle. However, the relationship between ENSO and the carbon cycle can be modulated by climate change due to anthropogenic forcing. We show herein that the sensitivity of the terrestrial carbon flux to ENSO will be enhanced under greenhouse warming by 44% (+/- 15%), indicating a future amplification of carbon-climate interactions. Separating the contributions of the changes in carbon sensitivity reveals that the response of land surface temperature to ENSO and the sensitivity of gross primary production to local temperature are significantly enhanced under greenhouse warming, thereby amplifying the ENSO-carbon-cycle coupling. In a warm climate, depletion of soil moisture increases temperature response in a given ENSO event. These findings suggest that the ENSO-related carbon cycle will be enhanced by hydroclimate changes caused by anthropogenic forcing.113Ysciescopu

    Flood Estimation and Prediction Using Particle Filters

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    Data assimilation methods have received increased attention to accomplish uncertainty assessment and enhancement of forecasting capability in various areas. Despite their potential, applicable software frameworks for probabilistic approaches and data assimilation are still limited because most hydrologic modeling software are based on a deterministic approach. In this study, we developed a hydrologic modeling framework for data assimilation, namely MPI-OHyMoS. While adapting object-oriented features of the original OHyMoS, MPI-OHyMoS allows user to build a probabilistic hydrologic model with data assimilation. In this software framework, sequential data assimilation based on particle filtering is available for any hydrologic models considering various sources of uncertainty originating from input forcing, parameters, and observations. Ensemble simulations are parallelized by a message passing interface (MPI), which can take advantage of high-performance computing (HPC) systems. Structure and implementation processes of data assimilation via MPI-OHyMoS are illustrated using a simple lumped model. We apply this software framework for uncertainty assessment of a distributed hydrologic model in synthetic and real experiment cases. In the synthetic experiment, dual state-parameter updating results in a reasonable estimation of parameters to cover synthetic true within their posterior distributions. In the real experiment, dual updating with identifiable parameters results in a reasonable agreement to the observed hydrograph with reduced uncertainty of parameters

    Effects of Particle Size and Cement Replacement of LCD Glass Powder in Concrete

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    The high quality liquid crystal display (LCD) processing waste glass (LPWG) generated from the manufacturing process of Korea’s LCD industries, having the world’s highest technological level and production, was finely ground into particles smaller than cement particles (higher fineness than OPC) to verify their applicability and performance as a replacement for cement. For a concrete mix having a W/B ratio of 0.44, cement was replaced with LPWG glass powder (LGP) at ratios of 5, 10, 15, and 20% (LGP12) and 5 and 10% (LGP5) according to the particle size to prepare test cylinder specimens, which were tested with respect to air contents, slump in fresh concrete, and compressive strength and splitting tensile strength of hardened concrete. The microstructure of the concrete specimens was analyzed through Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDX), and a Mercury Intrusion Porosimetry (MIP). Replacement of cement with LGP for cement could effectively decrease the quantity of cement used due to the excellent performance of LGP. It may positively contribute to the sustainable development of the cement industry as well as waste recycling and environment conservation on a national scale

    Numerical model of journal bearing lubrication considering a bending stiffness effect

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    An analysis for operating characteristics of journal bearing lubrication system is performed based on the numerical model. Dynamic bearing lubrication characteristics such as oil film pressure and thickness distribution can be analyzed through a numerical model with an integration of elastohydrodynamics and multi-flexible-body dynamics (MFBD). In particular, the oil film thickness variation by elastic deformation is considered in the elastohydrodynamic analysis by applying the bending stiffness effect of journal. And the oil film thickness variation by the bending stiffness effect is applied to the fluid governing equations to calculate the oil film pressure in the elastohydrodynamic lubrication region. A series of process proposed in this study is available for the analysis of realistic elastohydrodynamic lubrication phenomenon. Also, a numerical example for the journal bearing lubrication system is demonstrated and compared with the experimental results. The numerical results considering the bending stiffness effect show a good agreement with the experimental results

    Role of local air‐sea interaction in fire activity over Equatorial Asia

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    Fire activity in Equatorial Asia shows large interannual variability. Teleconnections by El Nino-Southern Oscillation and Indian Ocean Dipole are linked to drought and fire events; however, we found here that significant role of local Sea Surface Temperature (SST) over the Banda Sea in interannual variability of Equatorial Asian burned area in October even after removing the linear effects of teleconnections. October is the transient period from dry to wet season and strengthened seasonal circulation in October leads to a negative SST anomaly through Wind-Evaporation-SST mechanism. This anomalous local air-sea interaction sustains the dry season into October and stronger fire activity. Moreover, we found that the sensitivity of precipitation to SST is higher in October than in other months, hence fires in Equatorial Asia can be sensitively driven by local SST changes. Identification of this sensitivity will underpin better predictions of fire activity and air quality in Equatorial Asia.11Nsciescopu

    The effect of various design codes and dynamic magnification on buildings with torsional irregularity

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    Seismic provisions have utilized design eccentricities to reduce planar irregularities in lateral stiffness of buildings. In calculating a design eccentricity, the torsional amplification factor may be applied either to accidental eccentricity or to both inherent and accidental eccentricities according to design codes. In this paper, different code provisions and their impact on torsional responses of buildings are investigated using example buildings with various aspect ratios and inherent eccentricities. It was found that the design eccentricity in KBC-2009 using torsional amplification factor for only accidental eccentricity reflects the dynamic magnification more accurately than that in KBC-2006 using this factor for both inherent and accidental eccentricity. And dynamic magnification of a torsionally imbalanced building is affected by the size of seismic design force of response spectrum analysis than design eccentricity of equivalent static analysis in KBC-2009. In other words, design eccentricity including torsional amplification factor in KBC-2009 do not reflect the dynamic magnification accurately

    Atypical hemolytic uremic syndrome and eculizumab therapy in children

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    Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is mainly plasmapheresis or plasma infusion; however, many children with aHUS will progress to chronic kidney disease despite plasma therapy. Eculizumab is a newly developed biologic that blocks the terminal complement pathway and has been successfully used in the treatment of aHUS. Currently, several guidelines for aHUS, including the Korean guideline, recommend eculizumab as the first-line therapy in children with aHUS. Moreover, life-long eculizumab therapy is generally recommended. Further studies on discontinuation of eculizumab are needed
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