202 research outputs found
Decompounding on compact Lie groups
Noncommutative harmonic analysis is used to solve a nonparametric estimation
problem stated in terms of compound Poisson processes on compact Lie groups.
This problem of decompounding is a generalization of a similar classical
problem. The proposed solution is based on a char- acteristic function method.
The treated problem is important to recent models of the physical inverse
problem of multiple scattering.Comment: 26 pages, 3 figures, 25 reference
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Automated Software Quality Visualisation Using Fuzzy Logic Techniques
In the past decade there has been a concerted effort by the software industry to improve the quality of its products. This has led to the inception of various techniques with which to control and measure the process involved in software development. Methods like the Capability Maturity Model have introduced processes and strategies that require measurement in the form of software metrics. With the ever increasing number of software metrics being introduced by capability based processes, software development organisations are finding it more difficult to understand and interpret metric scores. This is particularly problematic for senior management and project managers where analysis of the actual data is not feasible. This paper proposes a method with which to visually represent metric scores so that managers can easily see how their organisation is performing relative to quality goals set for each type of metric. Acting primarily as a proof of concept and prototype, we suggest ways in which real customer needs can be translated into a feasible technical solution. The solution itself visualises metric scores in the form of a tree structure and utilises Fuzzy Logic techniques, XGMML, Web Services and the .NET Framework. Future work is proposed to extend the system from the prototype stage and to overcome a problem with the masking of poor scores
Comparison of depth cameras for three-dimensional Reconstruction in Medicine
KinectFusion is a typical three-dimensional reconstruction technique which enables generation of individual three-dimensional human models from consumer depth cameras for understanding body shapes. The aim of this study was to compare three-dimensional reconstruction results obtained using KinectFusion from data collected with two different types of depth camera (time-of-flight and stereoscopic cameras) and compare these results with those of a commercial three-dimensional scanning system to determine which type of depth camera gives improved reconstruction. Torso mannequins and machined aluminium cylinders were used as the test objects for this study. Two depth cameras, Microsoft Kinect V2 and Intel Realsense D435, were selected as the representatives of time-of-flight and stereoscopic cameras, respectively, to capture scan data for the reconstruction of three-dimensional point clouds by KinectFusion techniques. The results showed that both time-of-flight and stereoscopic cameras, using the developed rotating camera rig, provided repeatable body scanning data with minimal operator-induced error. However, the time-of-flight camera generated more accurate three-dimensional point clouds than the stereoscopic sensor. Thus, this suggests that applications requiring the generation of accurate three-dimensional human models by KinectFusion techniques should consider using a time-of-flight camera, such as the Microsoft Kinect V2, as the image capturing sensor
The prevalence and nature of cardiac arrhythmias in horses following general anaesthesia and surgery
Background:
The prevalence and nature of arrhythmias in horses following general anaesthesia and surgery is poorly documented. It has been proposed that horses undergoing emergency surgery for gastrointestinal disorders may be at particular risk of developing arrhythmias. Our primary objective was to determine the prevalence and nature of arrhythmias in horses following anaesthesia in a clinical setting and to establish if there was a difference in the prevalence of arrhythmias between horses with and without gastrointestinal disease undergoing surgery. Our secondary objective was to assess selected available risk factors for association with the development of arrhythmias following anaesthesia and surgery.
Methods:
Horses with evidence of gastrointestinal disease undergoing an exploratory laparotomy and horses with no evidence of gastrointestinal disease undergoing orthopaedic surgery between September 2009 and January 2011 were recruited prospectively. A telemetric electrocardiogram (ECG) was fitted to each horse following recovery from anaesthesia and left in place for 24 hours. Selected electrolytes were measured before, during and after surgery and data was extracted from clinical records for analysis. Recorded ECGs were analysed and the arrhythmias characterised. Multivariable logistic regression was used to identify risk factors associated with the development of arrhythmias.
Results:
Sixty-seven horses with gastrointestinal disease and 37 without gastrointestinal disease were recruited. Arrhythmias were very common during the post-operative period in both groups of horses. Supra-ventricular and bradyarrhythmias predominated in both groups. There were no significant differences in prevalence of any type of arrhythmias between the horses with or without gastrointestinal disease. Post-operative tachycardia and sodium derangements were associated with the development of any type of arrhythmia.
Conclusions:
This is the first study to report the prevalence of arrhythmias in horses during the post-operative period in a clinical setting. This study shows that arrhythmias are very common in horses following surgery. It showed no differences between those horses with or without gastrointestinal disease. Arrhythmias occurring in horses during the post-anaesthetic period require further investigation
2010 Ruby Yearbook
A digitized copy of the 2010 Ruby, the Ursinus College yearbook.https://digitalcommons.ursinus.edu/ruby/1113/thumbnail.jp
Sparse representation based pansharpening using trained dictionary,” Geos
Abstract-Sparse representation has been used to fuse highresolution panchromatic (HRP) and low-resolution multispectral (LRM) images. However, the approach faces the difficulty that the dictionary is generated from the high-resolution multispectral (HRM) images, which are unknown. In this letter, a two-step method is proposed to train the dictionary from the HRP and LRM images. In the first step, coarse HRM images are obtained by additive wavelet fusion method. The initial dictionary is composed of randomly sampled patches from the coarse HRM images. In the second step, a linear constraint K-SVD method is designed to train the dictionary to improve its representation ability. Experimental results using QuickBird and IKONOS data indicate that the trained dictionary yields comparable fusion products with raw-patch-dictionary sampled from HRM images
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Improving mood with psychoanalytic and cognitive therapies (IMPACT): a pragmatic effectiveness superiority trial to investigate whether specialised psychological treatment reduces the risk for relapse in adolescents with moderate to severe unipolar depression: study protocol for a randomised controlled trial.
BACKGROUND: Up to 70% of adolescents with moderate to severe unipolar major depression respond to psychological treatment plus Fluoxetine (20-50 mg) with symptom reduction and improved social function reported by 24 weeks after beginning treatment. Around 20% of non responders appear treatment resistant and 30% of responders relapse within 2 years. The specific efficacy of different psychological therapies and the moderators and mediators that influence risk for relapse are unclear. The cost-effectiveness and safety of psychological treatments remain poorly evaluated. METHODS/DESIGN: Improving Mood with Psychoanalytic and Cognitive Therapies, the IMPACT Study, will determine whether Cognitive Behavioural Therapy or Short Term Psychoanalytic Therapy is superior in reducing relapse compared with Specialist Clinical Care. The study is a multicentre pragmatic effectiveness superiority randomised clinical trial: Cognitive Behavioural Therapy consists of 20 sessions over 30 weeks, Short Term Psychoanalytic Psychotherapy 30 sessions over 30 weeks and Specialist Clinical Care 12 sessions over 20 weeks. We will recruit 540 patients with 180 randomised to each arm. Patients will be reassessed at 6, 12, 36, 52 and 86 weeks. Methodological aspects of the study are systematic recruitment, explicit inclusion criteria, reliability checks of assessments with control for rater shift, research assessors independent of treatment team and blind to randomization, analysis by intention to treat, data management using remote data entry, measures of quality assurance, advanced statistical analysis, manualised treatment protocols, checks of adherence and competence of therapists and assessment of cost-effectiveness. We will also determine whether time to recovery and/or relapse are moderated by variations in brain structure and function and selected genetic and hormone biomarkers taken at entry. DISCUSSION: The objective of this clinical trial is to determine whether there are specific effects of specialist psychotherapy that reduce relapse in unipolar major depression in adolescents and thereby costs of treatment to society. We also anticipate being able to utilise psychotherapy experience, neuroimaging, genetic and hormone measures to reveal what techniques and their protocols may work best for which patients. TRIAL REGISTRATION: Current Controlled Trials ISRCTN83033550.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial.
: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term effects and costs of psychological therapies on maintenance of reduced depression symptoms 12 months after treatment.
: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England. Adolescent patients (aged 11-17 years) with a diagnosis of DSM IV major depressive disorder were randomly assigned (1:1:1), via a web-based randomisation service, to receive cognitive behavioural therapy (CBT) or short-term psychoanalytical therapy versus a reference brief psychological intervention. Randomisation was stochastically minimised by age, sex, self-reported depression sum score, and region. Patients and clinicians were aware of group allocation, but allocation was concealed from outcome assessors. Patients were followed up and reassessed at weeks 6, 12, 36, 52, and 86 post-randomisation. The primary outcome was self-reported depression symptoms at weeks 36, 52, and 86, as measured with the self-reported Mood and Feelings Questionnaire (MFQ). Because our aim was to compare the two psychological therapies with the brief psychosocial intervention, we first established whether CBT was inferior to short-term psychoanalytical psychotherapy for the same outcome. Primary analysis was by intention to treat. This trial is registered with Current Controlled Trials, number ISRCTN83033550.
: Between June 29, 2010, and Jan 17, 2013, we randomly assigned 470 patients to receive the brief psychosocial intervention (n=158), CBT (n=155), or short-term psychoanalytical therapy (n=157); 465 patients comprised the intention-to-treat population. 392 (84%) patients had available data for primary analysis by the end of follow-up. Treatment fidelity and differentiation were established between the three interventions. The median number of treatment sessions differed significantly between patients in the brief psychosocial intervention group (n=6 [IQR 4-11]), CBT group (n=9 [5-14]), and short-term psychoanalytical therapy group (n=11 [5-23]; p<0·0001), but there was no difference between groups in the average duration of treatment (27·5 [SD 21·5], 24·9 [17·7], 27·9 [16·8] weeks, respectively; Kruskal-Wallis p=0·238). Self-reported depression symptoms did not differ significantly between patients given CBT and those given short-term psychoanalytical therapy at weeks 36 (treatment effect 0·179, 95% CI -3·731 to 4·088; p=0·929), 52 (0·307, -3·161 to 3·774; p=0·862), or 86 (0·578, -2·948 to 4·104; p=0·748). These two psychological treatments had no superiority effect compared with brief psychosocial intervention at weeks 36 (treatment effect -3·234, 95% CI -6·611 to 0·143; p=0·061), 52 (-2·806, -5·790 to 0·177; p=0·065), or 86 (-1·898, -4·922 to 1·126; p=0·219). Physical adverse events (self-reported breathing problems, sleep disturbances, drowsiness or tiredness, nausea, sweating, and being restless or overactive) did not differ between the groups. Total costs of the trial interventions did not differ significantly between treatment groups.
: We found no evidence for the superiority of CBT or short-term psychoanalytical therapy compared with a brief psychosocial intervention in maintenance of reduced depression symptoms 12 months after treatment. Short-term psychoanalytical therapy was as effective as CBT and, together with brief psychosocial intervention, offers additional patient choice for psychological therapy, alongside CBT, for adolescents with moderate to severe depression who are attending routine specialist CAMHS clinics.National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme, and the Department of Health
Effectiveness and cost-effectiveness of cognitive behavioural therapy and short-term psychoanalytic psychotherapy compared with brief psychological intervention in maintaining reduced depressive symptoms 12 months after end of treatment in adolescents with unipolar major depression (IMPACT):A pragmatic superiority randomised controlled trial.
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