29 research outputs found
Exohedral Physisorption of Ambient Moisture Scales Non-monotonically with Fiber Proximity in Aligned Carbon Nanotube Arrays
Here we present a study on the presence of physisorbed water on the surface of aligned carbon nanotubes (CNTs) in ambient conditions, where the wet CNT array mass can be more than 200% larger than that of dry CNTs, and modeling indicates that a water layer >5 nm thick can be present on the outer CNT surface. The experimentally observed nonlinear and non-monotonic dependence of the mass of adsorbed water on the CNT packing (volume fraction) originates from two competing modes. Physisorbed water cannot be neglected in the design and fabrication of materials and devices using nanowires/nanofibers, especially CNTs, and further experimental and ab initio studies on the influence of defects on the surface energies of CNTs, and nanowires/nanofibers in general, are necessary to understand the underlying physics and chemistry that govern this system.National Science Foundation (U.S.) (NSF Grant No. CMMI-1130437)National Science Foundation (U.S.) (NSF Award Number ECS-0335765)United States. Army Research Office (contract W911NF-07-D-0004
Impact of carbon nanotube length on electron transport in aligned carbon nanotube networks
Here, we quantify the electron transport properties of aligned carbon nanotube (CNT) networks as a function of the CNT length, where the electrical conductivities may be tuned by up to 10Ă with anisotropies exceeding 40%. Testing at elevated temperatures demonstrates that the aligned CNT networks have a negative temperature coefficient of resistance, and application of the fluctuation induced tunneling model leads to an activation energy of â14âmeV for electron tunneling at the CNT-CNT junctions. Since the tunneling activation energy is shown to be independent of both CNT length and orientation, the variation in electron transport is attributed to the number of CNT-CNT junctions an electron must tunnel through during its percolated path, which is proportional to the morphology of the aligned CNT network.United States. Army Research Office (contract W911NF-07-D-0004)United States. Army Research Office (contract W911NF-13-D-0001)United States. Air Force Office of Scientific Research (AFRL/RX contract FA8650-11-D-5800, Task Order 0003)National Science Foundation (U.S.) (NSF Award No. ECS-0335765)United States. Dept. of Defense (National Defense Science and Engineering Graduate Fellowship
Later life depression: attributions of causality and control in the life-review process
Bibliography: p. 186-209
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Breaking the Routine: Understanding the Interplay of Control Synergies and Reinforcement Learning to Improve Motor Training and Recovery in Neurologic Conditions
Neurological conditions, such as stroke and Parkinsonâs Disease are leading causes of chronic disability mainly due to the motor impairment. The current common solution for reducing motor impairment is to apply intensive movement practice, which is conducted by rehabilitation therapists. To aid patients and therapists in this goal, recent research efforts are focused on designing robotic devices and wearable sensors that help therapists promote optimal forms of practice without directly supervising training. However, it has been hypothesized that recovery may be limited when using these technologies because they encourage practice of âincorrectâ movements. Therefore, it is needed to further understand and characterize motor learning of âcorrectâ movements, in order to design beneficial mechanical devices that promote the recovery of patients. This dissertation provides insight into the optimal conditions for machine-assisted movement motor training by first studying the kinematics of movement recovery patterns after stroke to identify what are the âcorrectâ movements needed to progress in recovery, and second, by studying sensor-based feedback for promoting the practice of the desired movements. We first revisited a well-known but controversial model of early movement recovery after stroke â the proportional recovery (PR) model. We utilized a mathematical and behavioral approach to examine the PR model and explain why a portion of stroke survivors do not follow the proposed proportional recovery model. Our results showed that individuals âstuckâ in abnormal control synergies (the âflexionâ and âextensionâ arm synergies, defined by certain arm kinematics) recovered less than predicted by the proportional recovery model. Moreover, individuals who shifted from using abnormal control synergies to individuated joint control showed greater responsiveness to robot-assisted movement training.
Next, we analyzed clinical assessments of 319 personsâ abilities to perform âout-of-synergyâ and âin-synergyâ arm movements after chronic stroke using the Upper Extremity Fugl- Meyer (UEFM) scale. Our result showed that for some individuals with moderate impairment, rudimentary dexterity corresponded with reduced ability to move the arm in-synergy, i.e., there is a competition between the two types of movement. This result suggests that at least some individuals with a moderate impairment level may have not yet made the âswitchâ from practicing the in-synergy movement to more high-level control movements. In such cases, it would seem logical that rehabilitative movement training should focus on promoting those movements.
Based on these finding we then analyzed the effectiveness of three different rehabilitation training types on âbreaking outâ of synergy by introducing a new analysis of the UEFM assessment. We found that diverse (88 different exercises) arm/hand training was better at promoting the transition and was characterized with an early âbreakpointâ on the impairment scale.
We then asked how can we design an effective sensor-based feedback strategy that promotes a desired switch between movement patterns? We elected to investigate the use of reinforcement feedback, a motor training strategy that, while straightforward to implement with technology and capable of improving learning retention, has been neglected in rehabilitation technology. We did so by first studying the proposed paradigm in the context of shaping dance performance. We chose dancers because they are movement experts, i.e., individuals who work intensively for many years in order to learn a variety of complex movement abilities. Therefore, we hypothesized that they would have high levels of control flexibility, allowing them to move away from their established movement patterns toward novel patterns, and that, by studying this flexibility, we could better understand how to promote such flexibility. Surprisingly, the dancers found the proposed task to be difficult, and we found evidence of learning only in 14% of the motor practice sessions. The successful sessions were characterized by relatively low initial success rate, significantly more wrist than ankle movements in the initial period, and intermediate durations between successful movements. These findings provided guidance for how to make movement training with reinforcement feedback more effective.
Specifically, to better shape movements, we next developed an adaptive reinforcement feedback algorithm based on the concept of âhintsâ, which we implemented by initially presenting easier versions of the goal task, and then rewarding actions that progressively moved closer to the goal task. We tested this approach by comparing it with a conventional and fixed feedback approach with a group of college engineering students who played a novel computer game we developed based on the idea of dancing by moving a computer mouse. The adaptive algorithm caused a significantly higher initial success rate (as designed) but also caused a significantly higher final success rate therefore demonstrating a superior learning process. Moreover, there was a significant decrease in the reported frustration level for some objectives with adaptive reinforcement, although this effect was smaller than expected as frustration was more strongly associated with average success than initial success. Success in finding the target movement could not be predicted by initial success alone for the fixed feedback in this case. Surprisingly we also found that repeated exposure to reinforcement training promoted free movement diversity; a finding with implications related to the beneficial effect of diverse training with stroke patients mentioned before.
The results of this dissertation set the ground for development of a novel class of movement training technologies for individuals with neurological conditions based on adaptive reinforcement feedback. For training of the arm after stroke, we envision an implementation using a wearable sensor and an âarm danceâ paradigm in which the patient trains by moving the arm to music while receiving adaptive reinforcement feedback about movement individuation, speed, or smoothness. We believe that in this way we can better promote diverse but âcorrectâ movements, compared to existing robotic and wearable sensor training approaches. Another possible application is in the context of physical therapy for individuals with Parkinsonâs Disease, where the proposed training paradigm could be used to promote learning to make faster and bigger movements
Boulding, Kenneth E., and Laurence Senesh, eds., The Optimum Utilization of Knowledge: Making Knowledge Serve Human Betterment . Boulder, CO: Westview, 1983.
Contains articles relating the topic to education and to decision-making in social institutions
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Breaking the Routine: Understanding the Interplay of Control Synergies and Reinforcement Learning to Improve Motor Training and Recovery in Neurologic Conditions
Neurological conditions, such as stroke and Parkinsonâs Disease are leading causes of chronic disability mainly due to the motor impairment. The current common solution for reducing motor impairment is to apply intensive movement practice, which is conducted by rehabilitation therapists. To aid patients and therapists in this goal, recent research efforts are focused on designing robotic devices and wearable sensors that help therapists promote optimal forms of practice without directly supervising training. However, it has been hypothesized that recovery may be limited when using these technologies because they encourage practice of âincorrectâ movements. Therefore, it is needed to further understand and characterize motor learning of âcorrectâ movements, in order to design beneficial mechanical devices that promote the recovery of patients. This dissertation provides insight into the optimal conditions for machine-assisted movement motor training by first studying the kinematics of movement recovery patterns after stroke to identify what are the âcorrectâ movements needed to progress in recovery, and second, by studying sensor-based feedback for promoting the practice of the desired movements. We first revisited a well-known but controversial model of early movement recovery after stroke â the proportional recovery (PR) model. We utilized a mathematical and behavioral approach to examine the PR model and explain why a portion of stroke survivors do not follow the proposed proportional recovery model. Our results showed that individuals âstuckâ in abnormal control synergies (the âflexionâ and âextensionâ arm synergies, defined by certain arm kinematics) recovered less than predicted by the proportional recovery model. Moreover, individuals who shifted from using abnormal control synergies to individuated joint control showed greater responsiveness to robot-assisted movement training.
Next, we analyzed clinical assessments of 319 personsâ abilities to perform âout-of-synergyâ and âin-synergyâ arm movements after chronic stroke using the Upper Extremity Fugl- Meyer (UEFM) scale. Our result showed that for some individuals with moderate impairment, rudimentary dexterity corresponded with reduced ability to move the arm in-synergy, i.e., there is a competition between the two types of movement. This result suggests that at least some individuals with a moderate impairment level may have not yet made the âswitchâ from practicing the in-synergy movement to more high-level control movements. In such cases, it would seem logical that rehabilitative movement training should focus on promoting those movements.
Based on these finding we then analyzed the effectiveness of three different rehabilitation training types on âbreaking outâ of synergy by introducing a new analysis of the UEFM assessment. We found that diverse (88 different exercises) arm/hand training was better at promoting the transition and was characterized with an early âbreakpointâ on the impairment scale.
We then asked how can we design an effective sensor-based feedback strategy that promotes a desired switch between movement patterns? We elected to investigate the use of reinforcement feedback, a motor training strategy that, while straightforward to implement with technology and capable of improving learning retention, has been neglected in rehabilitation technology. We did so by first studying the proposed paradigm in the context of shaping dance performance. We chose dancers because they are movement experts, i.e., individuals who work intensively for many years in order to learn a variety of complex movement abilities. Therefore, we hypothesized that they would have high levels of control flexibility, allowing them to move away from their established movement patterns toward novel patterns, and that, by studying this flexibility, we could better understand how to promote such flexibility. Surprisingly, the dancers found the proposed task to be difficult, and we found evidence of learning only in 14% of the motor practice sessions. The successful sessions were characterized by relatively low initial success rate, significantly more wrist than ankle movements in the initial period, and intermediate durations between successful movements. These findings provided guidance for how to make movement training with reinforcement feedback more effective.
Specifically, to better shape movements, we next developed an adaptive reinforcement feedback algorithm based on the concept of âhintsâ, which we implemented by initially presenting easier versions of the goal task, and then rewarding actions that progressively moved closer to the goal task. We tested this approach by comparing it with a conventional and fixed feedback approach with a group of college engineering students who played a novel computer game we developed based on the idea of dancing by moving a computer mouse. The adaptive algorithm caused a significantly higher initial success rate (as designed) but also caused a significantly higher final success rate therefore demonstrating a superior learning process. Moreover, there was a significant decrease in the reported frustration level for some objectives with adaptive reinforcement, although this effect was smaller than expected as frustration was more strongly associated with average success than initial success. Success in finding the target movement could not be predicted by initial success alone for the fixed feedback in this case. Surprisingly we also found that repeated exposure to reinforcement training promoted free movement diversity; a finding with implications related to the beneficial effect of diverse training with stroke patients mentioned before.
The results of this dissertation set the ground for development of a novel class of movement training technologies for individuals with neurological conditions based on adaptive reinforcement feedback. For training of the arm after stroke, we envision an implementation using a wearable sensor and an âarm danceâ paradigm in which the patient trains by moving the arm to music while receiving adaptive reinforcement feedback about movement individuation, speed, or smoothness. We believe that in this way we can better promote diverse but âcorrectâ movements, compared to existing robotic and wearable sensor training approaches. Another possible application is in the context of physical therapy for individuals with Parkinsonâs Disease, where the proposed training paradigm could be used to promote learning to make faster and bigger movements
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Breaking Proportional Recovery After Stroke
People with hemiparesis after stroke appear to recover 70% to 80% of the difference between their baseline and the maximum upper extremity Fugl-Meyer (UEFM) score, a phenomenon called proportional recovery (PR). Two recent commentaries explained that PR should be expected because of mathematical coupling between the baseline and change score. Here we ask, If mathematical coupling encourages PR, why do a fraction of stroke patients (the "nonfitters") not exhibit PR? At the neuroanatomical level of analysis, this question was answered by Byblow et al-nonfitters lack corticospinal tract (CST) integrity at baseline-but here we address the mathematical and behavioral causes. We first derive a new interpretation of the slope of PR: It is the average probability of scoring across remaining scale items at follow-up. PR therefore breaks when enough test items are discretely more difficult for a patient at follow-up, flattening the slope of recovery. For the UEFM, we show that nonfitters are most unlikely to recover the ability to score on the test items related to wrist/hand dexterity, shoulder flexion without bending the elbow, and finger-to-nose movement, supporting the finding that nonfitters lack CST integrity. However, we also show that a subset of nonfitters respond better to robotic movement training in the chronic phase of stroke. These persons are just able to move the arm out of the flexion synergy and pick up small blocks, both markers of CST integrity. Nonfitters therefore raise interesting questions about CST function and the basis for response to intensive movement training
Saturation of the yield limit of copper irradiated with charged particles
22.00; Translated from Russian (Fiz. Khim. Obrab. Mater. 1989 v. 23(2) p. 5-10)Available from British Library Document Supply Centre- DSC:9023.19(VR-Trans--4492)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
Breaking Proportional Recovery After Stroke
People with hemiparesis after stroke appear to recover 70% to 80% of the difference between their baseline and the maximum upper extremity Fugl-Meyer (UEFM) score, a phenomenon called proportional recovery (PR). Two recent commentaries explained that PR should be expected because of mathematical coupling between the baseline and change score. Here we ask, If mathematical coupling encourages PR, why do a fraction of stroke patients (the "nonfitters") not exhibit PR? At the neuroanatomical level of analysis, this question was answered by Byblow et al-nonfitters lack corticospinal tract (CST) integrity at baseline-but here we address the mathematical and behavioral causes. We first derive a new interpretation of the slope of PR: It is the average probability of scoring across remaining scale items at follow-up. PR therefore breaks when enough test items are discretely more difficult for a patient at follow-up, flattening the slope of recovery. For the UEFM, we show that nonfitters are most unlikely to recover the ability to score on the test items related to wrist/hand dexterity, shoulder flexion without bending the elbow, and finger-to-nose movement, supporting the finding that nonfitters lack CST integrity. However, we also show that a subset of nonfitters respond better to robotic movement training in the chronic phase of stroke. These persons are just able to move the arm out of the flexion synergy and pick up small blocks, both markers of CST integrity. Nonfitters therefore raise interesting questions about CST function and the basis for response to intensive movement training